Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TNKS1BP1 (tankyrase 1 binding protein 1)

Identity

Alias (NCBI)TAB182
HGNC (Hugo) TNKS1BP1
HGNC Alias symbTAB182
KIAA1741
FLJ45975
HGNC Previous nametankyrase 1 binding protein 1, 182kDa
LocusID (NCBI) 85456
Atlas_Id 46001
Location 11q12.1  [Link to chromosome band 11q12]
Location_base_pair Starts at 57299642 and ends at 57324952 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANKDD1A (15q22.31) / TNKS1BP1 (11q12.1)FHL2 (2q12.1) / TNKS1BP1 (11q12.1)IGFBP4 (17q21.2) / TNKS1BP1 (11q12.1)
NLGN3 (Xq13.1) / TNKS1BP1 (11q12.1)TNKS1BP1 (11q12.1) / LRCH4 (7q22.1)TNKS1BP1 (11q12.1) / MACF1 (1p34.3)
TNKS1BP1 (11q12.1) / PSG3 (19q13.2)TNKS1BP1 (11q12.1) / XCR1 (3p21.31)ZNF207 (17q11.2) / TNKS1BP1 (11q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TNKS1BP1   19081
Cards
Entrez_Gene (NCBI)TNKS1BP1  85456  tankyrase 1 binding protein 1
AliasesTAB182
GeneCards (Weizmann)TNKS1BP1
Ensembl hg19 (Hinxton)ENSG00000149115 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149115 [Gene_View]  ENSG00000149115 [Sequence]  chr11:57299642-57324952 [Contig_View]  TNKS1BP1 [Vega]
ICGC DataPortalENSG00000149115
TCGA cBioPortalTNKS1BP1
AceView (NCBI)TNKS1BP1
Genatlas (Paris)TNKS1BP1
WikiGenes85456
SOURCE (Princeton)TNKS1BP1
Genetics Home Reference (NIH)TNKS1BP1
Genomic and cartography
GoldenPath hg38 (UCSC)TNKS1BP1  -     chr11:57299642-57324952 -  11q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TNKS1BP1  -     11q12.1   [Description]    (hg19-Feb_2009)
GoldenPathTNKS1BP1 - 11q12.1 [CytoView hg19]  TNKS1BP1 - 11q12.1 [CytoView hg38]
ImmunoBaseENSG00000149115
genome Data Viewer NCBITNKS1BP1 [Mapview hg19]  
OMIM607104   
Gene and transcription
Genbank (Entrez)AA614752 AB051528 AF441771 AK074113 AK124903
RefSeq transcript (Entrez)NM_033396
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TNKS1BP1
Alternative Splicing GalleryENSG00000149115
Gene ExpressionTNKS1BP1 [ NCBI-GEO ]   TNKS1BP1 [ EBI - ARRAY_EXPRESS ]   TNKS1BP1 [ SEEK ]   TNKS1BP1 [ MEM ]
Gene Expression Viewer (FireBrowse)TNKS1BP1 [ Firebrowse - Broad ]
GenevisibleExpression of TNKS1BP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85456
GTEX Portal (Tissue expression)TNKS1BP1
Human Protein AtlasENSG00000149115-TNKS1BP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C0C2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C0C2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C0C2
Splice isoforms : SwissVarQ9C0C2
PhosPhoSitePlusQ9C0C2
Domains : Interpro (EBI)Tankyrase-bd_C    TNKS1BP1-like   
Domain families : Pfam (Sanger)Tankyrase_bdg_C (PF15327)   
Domain families : Pfam (NCBI)pfam15327   
Domain families : Smart (EMBL)Tankyrase_bdg_C (SM01319)  
Conserved Domain (NCBI)TNKS1BP1
DMDM Disease mutations85456
Blocks (Seattle)TNKS1BP1
SuperfamilyQ9C0C2
Human Protein Atlas [tissue]ENSG00000149115-TNKS1BP1 [tissue]
Peptide AtlasQ9C0C2
HPRD06164
IPIIPI00304589   IPI00847646   IPI00384104   IPI00977698   IPI00975931   
Protein Interaction databases
DIP (DOE-UCLA)Q9C0C2
IntAct (EBI)Q9C0C2
FunCoupENSG00000149115
BioGRIDTNKS1BP1
STRING (EMBL)TNKS1BP1
ZODIACTNKS1BP1
Ontologies - Pathways
QuickGOQ9C0C2
Ontology : AmiGOnuclear-transcribed mRNA poly(A) tail shortening  protein binding  nucleus  nuclear heterochromatin  cytoplasm  cytosol  cytoskeleton  adherens junction  double-strand break repair  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  telomere maintenance via telomerase  positive regulation of peptidyl-threonine phosphorylation  enzyme binding  CCR4-NOT complex  positive regulation of protein autophosphorylation  positive regulation of peptidyl-serine phosphorylation  protein-containing complex binding  cadherin binding  cellular response to ionizing radiation  ankyrin repeat binding  ankyrin repeat binding  
Ontology : EGO-EBInuclear-transcribed mRNA poly(A) tail shortening  protein binding  nucleus  nuclear heterochromatin  cytoplasm  cytosol  cytoskeleton  adherens junction  double-strand break repair  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  telomere maintenance via telomerase  positive regulation of peptidyl-threonine phosphorylation  enzyme binding  CCR4-NOT complex  positive regulation of protein autophosphorylation  positive regulation of peptidyl-serine phosphorylation  protein-containing complex binding  cadherin binding  cellular response to ionizing radiation  ankyrin repeat binding  ankyrin repeat binding  
NDEx NetworkTNKS1BP1
Atlas of Cancer Signalling NetworkTNKS1BP1
Wikipedia pathwaysTNKS1BP1
Orthology - Evolution
OrthoDB85456
GeneTree (enSembl)ENSG00000149115
Phylogenetic Trees/Animal Genes : TreeFamTNKS1BP1
HOGENOMQ9C0C2
Homologs : HomoloGeneTNKS1BP1
Homology/Alignments : Family Browser (UCSC)TNKS1BP1
Gene fusions - Rearrangements
Fusion : QuiverTNKS1BP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNKS1BP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNKS1BP1
dbVarTNKS1BP1
ClinVarTNKS1BP1
1000_GenomesTNKS1BP1 
Exome Variant ServerTNKS1BP1
GNOMAD BrowserENSG00000149115
Varsome BrowserTNKS1BP1
Genetic variants : HAPMAP85456
Genomic Variants (DGV)TNKS1BP1 [DGVbeta]
DECIPHERTNKS1BP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTNKS1BP1 
Mutations
ICGC Data PortalTNKS1BP1 
TCGA Data PortalTNKS1BP1 
Broad Tumor PortalTNKS1BP1
OASIS PortalTNKS1BP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNKS1BP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTNKS1BP1
Mutations and Diseases : HGMDTNKS1BP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNKS1BP1
DgiDB (Drug Gene Interaction Database)TNKS1BP1
DoCM (Curated mutations)TNKS1BP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNKS1BP1 (select a term)
intoGenTNKS1BP1
Cancer3DTNKS1BP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607104   
Orphanet
DisGeNETTNKS1BP1
MedgenTNKS1BP1
Genetic Testing Registry TNKS1BP1
NextProtQ9C0C2 [Medical]
TSGene85456
GENETestsTNKS1BP1
Target ValidationTNKS1BP1
Huge Navigator TNKS1BP1 [HugePedia]
snp3D : Map Gene to Disease85456
BioCentury BCIQTNKS1BP1
ClinGenTNKS1BP1
Clinical trials, drugs, therapy
Protein Interactions : CTD85456
Pharm GKB GenePA38789
Clinical trialTNKS1BP1
Miscellaneous
canSAR (ICR)TNKS1BP1 (select the gene name)
HarmonizomeTNKS1BP1
DataMed IndexTNKS1BP1
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNKS1BP1
EVEXTNKS1BP1
GoPubMedTNKS1BP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 15:40:06 CEST 2020
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