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TNNC2 (troponin C type 2 (fast))

Identity

Alias_namestroponin C type 2 (fast)
Other alias-
HGNC (Hugo) TNNC2
LocusID (NCBI) 7125
Atlas_Id 75037
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 44451855 and ends at 44455953 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EFCAB8 () / TNNC2 (20q13.12)MAP4 (3p21.31) / TNNC2 (20q13.12)TNNC2 (20q13.12) / HSPB1 (7q11.23)
TNNC2 (20q13.12) / PRMT2 (21q22.3)TNNC2 (20q13.12) / TNNC2 (20q13.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TNNC2   11944
Cards
Entrez_Gene (NCBI)TNNC2  7125  troponin C type 2 (fast)
Aliases
GeneCards (Weizmann)TNNC2
Ensembl hg19 (Hinxton)ENSG00000101470 [Gene_View]  chr20:44451855-44455953 [Contig_View]  TNNC2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000101470 [Gene_View]  chr20:44451855-44455953 [Contig_View]  TNNC2 [Vega]
ICGC DataPortalENSG00000101470
TCGA cBioPortalTNNC2
AceView (NCBI)TNNC2
Genatlas (Paris)TNNC2
WikiGenes7125
SOURCE (Princeton)TNNC2
Genetics Home Reference (NIH)TNNC2
Genomic and cartography
GoldenPath hg19 (UCSC)TNNC2  -     chr20:44451855-44455953 -  20q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TNNC2  -     20q13.12   [Description]    (hg38-Dec_2013)
EnsemblTNNC2 - 20q13.12 [CytoView hg19]  TNNC2 - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBITNNC2 [Mapview hg19]  TNNC2 [Mapview hg38]
OMIM191039   
Gene and transcription
Genbank (Entrez)AI080746 AK291323 AK300665 BC005323 BU854061
RefSeq transcript (Entrez)NM_003279
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)TNNC2
Cluster EST : UnigeneHs.182421 [ NCBI ]
CGAP (NCI)Hs.182421
Alternative Splicing GalleryENSG00000101470
Gene ExpressionTNNC2 [ NCBI-GEO ]   TNNC2 [ EBI - ARRAY_EXPRESS ]   TNNC2 [ SEEK ]   TNNC2 [ MEM ]
Gene Expression Viewer (FireBrowse)TNNC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7125
GTEX Portal (Tissue expression)TNNC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02585   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02585  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02585
Splice isoforms : SwissVarP02585
PhosPhoSitePlusP02585
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom   
Domain families : Pfam (Sanger)EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam13499   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)TNNC2
DMDM Disease mutations7125
Blocks (Seattle)TNNC2
SuperfamilyP02585
Human Protein AtlasENSG00000101470
Peptide AtlasP02585
HPRD08929
IPIIPI00219796   IPI00646205   
Protein Interaction databases
DIP (DOE-UCLA)P02585
IntAct (EBI)P02585
FunCoupENSG00000101470
BioGRIDTNNC2
STRING (EMBL)TNNC2
ZODIACTNNC2
Ontologies - Pathways
QuickGOP02585
Ontology : AmiGOskeletal muscle contraction  actin binding  calcium ion binding  protein binding  cytosol  troponin complex  regulation of muscle contraction  muscle filament sliding  
Ontology : EGO-EBIskeletal muscle contraction  actin binding  calcium ion binding  protein binding  cytosol  troponin complex  regulation of muscle contraction  muscle filament sliding  
Pathways : KEGGCalcium signaling pathway   
NDEx NetworkTNNC2
Atlas of Cancer Signalling NetworkTNNC2
Wikipedia pathwaysTNNC2
Orthology - Evolution
OrthoDB7125
GeneTree (enSembl)ENSG00000101470
Phylogenetic Trees/Animal Genes : TreeFamTNNC2
HOVERGENP02585
HOGENOMP02585
Homologs : HomoloGeneTNNC2
Homology/Alignments : Family Browser (UCSC)TNNC2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNNC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNNC2
dbVarTNNC2
ClinVarTNNC2
1000_GenomesTNNC2 
Exome Variant ServerTNNC2
ExAC (Exome Aggregation Consortium)TNNC2 (select the gene name)
Genetic variants : HAPMAP7125
Genomic Variants (DGV)TNNC2 [DGVbeta]
DECIPHER (Syndromes)20:44451855-44455953  ENSG00000101470
CONAN: Copy Number AnalysisTNNC2 
Mutations
ICGC Data PortalTNNC2 
TCGA Data PortalTNNC2 
Broad Tumor PortalTNNC2
OASIS PortalTNNC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNNC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNNC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNNC2
DgiDB (Drug Gene Interaction Database)TNNC2
DoCM (Curated mutations)TNNC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNNC2 (select a term)
intoGenTNNC2
Cancer3DTNNC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM191039   
Orphanet
MedgenTNNC2
Genetic Testing Registry TNNC2
NextProtP02585 [Medical]
TSGene7125
GENETestsTNNC2
Huge Navigator TNNC2 [HugePedia]
snp3D : Map Gene to Disease7125
BioCentury BCIQTNNC2
ClinGenTNNC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7125
Chemical/Pharm GKB GenePA36633
Clinical trialTNNC2
Miscellaneous
canSAR (ICR)TNNC2 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNNC2
EVEXTNNC2
GoPubMedTNNC2
iHOPTNNC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:49:15 CET 2017

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