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TNNI1 (troponin I1, slow skeletal type)

Identity

Alias (NCBI)SSTNI
TNN1
HGNC (Hugo) TNNI1
HGNC Previous nametroponin I type 1 (skeletal, slow)
LocusID (NCBI) 7135
Atlas_Id 57856
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 201403784 and ends at 201421730 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LEFTY1 (1q42.12) / TNNI1 (1q32.1)TNNI1 (1q32.1) / TNNI1 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TNNI1   11945
Cards
Entrez_Gene (NCBI)TNNI1    troponin I1, slow skeletal type
AliasesSSTNI; TNN1
GeneCards (Weizmann)TNNI1
Ensembl hg19 (Hinxton)ENSG00000159173 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159173 [Gene_View]  ENSG00000159173 [Sequence]  chr1:201403784-201421730 [Contig_View]  TNNI1 [Vega]
ICGC DataPortalENSG00000159173
TCGA cBioPortalTNNI1
AceView (NCBI)TNNI1
Genatlas (Paris)TNNI1
SOURCE (Princeton)TNNI1
Genetics Home Reference (NIH)TNNI1
Genomic and cartography
GoldenPath hg38 (UCSC)TNNI1  -     chr1:201403784-201421730 -  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TNNI1  -     1q32.1   [Description]    (hg19-Feb_2009)
GoldenPathTNNI1 - 1q32.1 [CytoView hg19]  TNNI1 - 1q32.1 [CytoView hg38]
ImmunoBaseENSG00000159173
Genome Data Viewer NCBITNNI1 [Mapview hg19]  
OMIM191042   
Gene and transcription
Genbank (Entrez)AJ315823 AK123965 AK223588 AK311896 AL831820
RefSeq transcript (Entrez)NM_003281
Consensus coding sequences : CCDS (NCBI)TNNI1
Gene ExpressionTNNI1 [ NCBI-GEO ]   TNNI1 [ EBI - ARRAY_EXPRESS ]   TNNI1 [ SEEK ]   TNNI1 [ MEM ]
Gene Expression Viewer (FireBrowse)TNNI1 [ Firebrowse - Broad ]
GenevisibleExpression of TNNI1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7135
GTEX Portal (Tissue expression)TNNI1
Human Protein AtlasENSG00000159173-TNNI1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19237   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP19237  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19237
PhosPhoSitePlusP19237
Domains : Interpro (EBI)Troponin    Troponin_sf   
Domain families : Pfam (Sanger)Troponin (PF00992)   
Domain families : Pfam (NCBI)pfam00992   
Conserved Domain (NCBI)TNNI1
SuperfamilyP19237
AlphaFold pdb e-kbP19237   
Human Protein Atlas [tissue]ENSG00000159173-TNNI1 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)P19237
IntAct (EBI)P19237
BioGRIDTNNI1
STRING (EMBL)TNNI1
ZODIACTNNI1
Ontologies - Pathways
QuickGOP19237
Ontology : AmiGOskeletal muscle contraction  actin binding  protein binding  cytosol  troponin complex  troponin complex  muscle contraction  regulation of striated muscle contraction  transition between fast and slow fiber  muscle filament sliding  metal ion binding  ventricular cardiac muscle tissue morphogenesis  cardiac muscle contraction  
Ontology : EGO-EBIskeletal muscle contraction  actin binding  protein binding  cytosol  troponin complex  troponin complex  muscle contraction  regulation of striated muscle contraction  transition between fast and slow fiber  muscle filament sliding  metal ion binding  ventricular cardiac muscle tissue morphogenesis  cardiac muscle contraction  
Pathways : BIOCARTAActions of Nitric Oxide in the Heart [Genes]   
NDEx NetworkTNNI1
Atlas of Cancer Signalling NetworkTNNI1
Wikipedia pathwaysTNNI1
Orthology - Evolution
OrthoDB7135
GeneTree (enSembl)ENSG00000159173
Phylogenetic Trees/Animal Genes : TreeFamTNNI1
Homologs : HomoloGeneTNNI1
Homology/Alignments : Family Browser (UCSC)TNNI1
Gene fusions - Rearrangements
Fusion : QuiverTNNI1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNNI1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNNI1
dbVarTNNI1
ClinVarTNNI1
MonarchTNNI1
1000_GenomesTNNI1 
Exome Variant ServerTNNI1
GNOMAD BrowserENSG00000159173
Varsome BrowserTNNI1
ACMGTNNI1 variants
VarityP19237
Genomic Variants (DGV)TNNI1 [DGVbeta]
DECIPHERTNNI1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTNNI1 
Mutations
ICGC Data PortalTNNI1 
TCGA Data PortalTNNI1 
Broad Tumor PortalTNNI1
OASIS PortalTNNI1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNNI1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTNNI1
Mutations and Diseases : HGMDTNNI1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTNNI1
DgiDB (Drug Gene Interaction Database)TNNI1
DoCM (Curated mutations)TNNI1
CIViC (Clinical Interpretations of Variants in Cancer)TNNI1
Cancer3DTNNI1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM191042   
Orphanet
DisGeNETTNNI1
MedgenTNNI1
Genetic Testing Registry TNNI1
NextProtP19237 [Medical]
GENETestsTNNI1
Target ValidationTNNI1
Huge Navigator TNNI1 [HugePedia]
ClinGenTNNI1
Clinical trials, drugs, therapy
MyCancerGenomeTNNI1
Protein Interactions : CTDTNNI1
Pharm GKB GenePA36634
PharosP19237
Clinical trialTNNI1
Miscellaneous
canSAR (ICR)TNNI1
HarmonizomeTNNI1
DataMed IndexTNNI1
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTNNI1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:35:48 CEST 2021

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