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TNP2 (transition protein 2)

Identity

Alias_namestransition protein 2 (during histone to protamine replacement)
Alias_symbol (synonym)TP2
Other alias
HGNC (Hugo) TNP2
LocusID (NCBI) 7142
Atlas_Id 75040
Location 16p13.13  [Link to chromosome band 16p13]
Location_base_pair Starts at 11267857 and ends at 11269303 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TNP2   11952
Cards
Entrez_Gene (NCBI)TNP2  7142  transition protein 2
AliasesTP2
GeneCards (Weizmann)TNP2
Ensembl hg19 (Hinxton)ENSG00000178279 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178279 [Gene_View]  chr16:11267857-11269303 [Contig_View]  TNP2 [Vega]
ICGC DataPortalENSG00000178279
TCGA cBioPortalTNP2
AceView (NCBI)TNP2
Genatlas (Paris)TNP2
WikiGenes7142
SOURCE (Princeton)TNP2
Genetics Home Reference (NIH)TNP2
Genomic and cartography
GoldenPath hg38 (UCSC)TNP2  -     chr16:11267857-11269303 -  16p13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TNP2  -     16p13.13   [Description]    (hg19-Feb_2009)
EnsemblTNP2 - 16p13.13 [CytoView hg19]  TNP2 - 16p13.13 [CytoView hg38]
Mapping of homologs : NCBITNP2 [Mapview hg19]  TNP2 [Mapview hg38]
OMIM190232   
Gene and transcription
Genbank (Entrez)AI220577 BC096135 BC096136 BC096137 BX282422
RefSeq transcript (Entrez)NM_005425
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TNP2
Cluster EST : UnigeneHs.513349 [ NCBI ]
CGAP (NCI)Hs.513349
Alternative Splicing GalleryENSG00000178279
Gene ExpressionTNP2 [ NCBI-GEO ]   TNP2 [ EBI - ARRAY_EXPRESS ]   TNP2 [ SEEK ]   TNP2 [ MEM ]
Gene Expression Viewer (FireBrowse)TNP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7142
GTEX Portal (Tissue expression)TNP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ05952   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ05952  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ05952
Splice isoforms : SwissVarQ05952
PhosPhoSitePlusQ05952
Domaine pattern : Prosite (Expaxy)TP2_1 (PS00970)    TP2_2 (PS00971)   
Domains : Interpro (EBI)TP2   
Domain families : Pfam (Sanger)TP2 (PF01254)   
Domain families : Pfam (NCBI)pfam01254   
Conserved Domain (NCBI)TNP2
DMDM Disease mutations7142
Blocks (Seattle)TNP2
SuperfamilyQ05952
Human Protein AtlasENSG00000178279
Peptide AtlasQ05952
HPRD01831
IPIIPI00016783   
Protein Interaction databases
DIP (DOE-UCLA)Q05952
IntAct (EBI)Q05952
FunCoupENSG00000178279
BioGRIDTNP2
STRING (EMBL)TNP2
ZODIACTNP2
Ontologies - Pathways
QuickGOQ05952
Ontology : AmiGOnucleosome  male germ cell nucleus  DNA binding  nucleolus  multicellular organism development  spermatogenesis  acrosome reaction  penetration of zona pellucida  zinc ion binding  cell differentiation  
Ontology : EGO-EBInucleosome  male germ cell nucleus  DNA binding  nucleolus  multicellular organism development  spermatogenesis  acrosome reaction  penetration of zona pellucida  zinc ion binding  cell differentiation  
NDEx NetworkTNP2
Atlas of Cancer Signalling NetworkTNP2
Wikipedia pathwaysTNP2
Orthology - Evolution
OrthoDB7142
GeneTree (enSembl)ENSG00000178279
Phylogenetic Trees/Animal Genes : TreeFamTNP2
HOVERGENQ05952
HOGENOMQ05952
Homologs : HomoloGeneTNP2
Homology/Alignments : Family Browser (UCSC)TNP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNP2
dbVarTNP2
ClinVarTNP2
1000_GenomesTNP2 
Exome Variant ServerTNP2
ExAC (Exome Aggregation Consortium)TNP2 (select the gene name)
Genetic variants : HAPMAP7142
Genomic Variants (DGV)TNP2 [DGVbeta]
DECIPHERTNP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTNP2 
Mutations
ICGC Data PortalTNP2 
TCGA Data PortalTNP2 
Broad Tumor PortalTNP2
OASIS PortalTNP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNP2
DgiDB (Drug Gene Interaction Database)TNP2
DoCM (Curated mutations)TNP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNP2 (select a term)
intoGenTNP2
Cancer3DTNP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM190232   
Orphanet
MedgenTNP2
Genetic Testing Registry TNP2
NextProtQ05952 [Medical]
TSGene7142
GENETestsTNP2
Target ValidationTNP2
Huge Navigator TNP2 [HugePedia]
snp3D : Map Gene to Disease7142
BioCentury BCIQTNP2
ClinGenTNP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7142
Chemical/Pharm GKB GenePA36641
Clinical trialTNP2
Miscellaneous
canSAR (ICR)TNP2 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNP2
EVEXTNP2
GoPubMedTNP2
iHOPTNP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:46:40 CEST 2017
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