Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TNPO2 (transportin 2)

Identity

Alias_symbol (synonym)IPO3
KPNB2B
FLJ12155
TRN2
Other alias
HGNC (Hugo) TNPO2
LocusID (NCBI) 30000
Atlas_Id 51677
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 12810008 and ends at 12834810 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LDLR (19p13.2) / TNPO2 (19p13.2)TNPO2 (19p13.2) / RFX1 (19p13.12)TNPO2 (19p13.2) / TNPO2 (19p13.2)
LDLR 19p13.2 / TNPO2 19p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TNPO2   19998
Cards
Entrez_Gene (NCBI)TNPO2  30000  transportin 2
AliasesIPO3; KPNB2B; TRN2
GeneCards (Weizmann)TNPO2
Ensembl hg19 (Hinxton)ENSG00000105576 [Gene_View]  chr19:12810008-12834810 [Contig_View]  TNPO2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000105576 [Gene_View]  chr19:12810008-12834810 [Contig_View]  TNPO2 [Vega]
ICGC DataPortalENSG00000105576
TCGA cBioPortalTNPO2
AceView (NCBI)TNPO2
Genatlas (Paris)TNPO2
WikiGenes30000
SOURCE (Princeton)TNPO2
Genetics Home Reference (NIH)TNPO2
Genomic and cartography
GoldenPath hg19 (UCSC)TNPO2  -     chr19:12810008-12834810 -  19p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TNPO2  -     19p13.2   [Description]    (hg38-Dec_2013)
EnsemblTNPO2 - 19p13.2 [CytoView hg19]  TNPO2 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBITNPO2 [Mapview hg19]  TNPO2 [Mapview hg38]
OMIM603002   
Gene and transcription
Genbank (Entrez)AB210011 AF007748 AF019039 AK022217 AK056183
RefSeq transcript (Entrez)NM_001136195 NM_001136196 NM_013433
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929414
Consensus coding sequences : CCDS (NCBI)TNPO2
Cluster EST : UnigeneHs.714402 [ NCBI ]
CGAP (NCI)Hs.714402
Alternative Splicing GalleryENSG00000105576
Gene ExpressionTNPO2 [ NCBI-GEO ]   TNPO2 [ EBI - ARRAY_EXPRESS ]   TNPO2 [ SEEK ]   TNPO2 [ MEM ]
Gene Expression Viewer (FireBrowse)TNPO2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)30000
GTEX Portal (Tissue expression)TNPO2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14787   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14787  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14787
Splice isoforms : SwissVarO14787
PhosPhoSitePlusO14787
Domains : Interpro (EBI)ARM-like    ARM-type_fold    HEAT    Importin-beta_N   
Domain families : Pfam (Sanger)HEAT (PF02985)    IBN_N (PF03810)   
Domain families : Pfam (NCBI)pfam02985    pfam03810   
Domain families : Smart (EMBL)IBN_N (SM00913)  
Conserved Domain (NCBI)TNPO2
DMDM Disease mutations30000
Blocks (Seattle)TNPO2
SuperfamilyO14787
Human Protein AtlasENSG00000105576
Peptide AtlasO14787
IPIIPI00409698   IPI00164417   IPI00903321   IPI01009384   IPI01010660   IPI00419856   IPI00975898   
Protein Interaction databases
DIP (DOE-UCLA)O14787
IntAct (EBI)O14787
FunCoupENSG00000105576
BioGRIDTNPO2
STRING (EMBL)TNPO2
ZODIACTNPO2
Ontologies - Pathways
QuickGOO14787
Ontology : AmiGOprotein import into nucleus, docking  protein import into nucleus, translocation  protein binding  nucleus  cytoplasm  NLS-bearing protein import into nucleus  ribosomal protein import into nucleus  nuclear localization sequence binding  Ran GTPase binding  protein transporter activity  nuclear membrane  nuclear periphery  
Ontology : EGO-EBIprotein import into nucleus, docking  protein import into nucleus, translocation  protein binding  nucleus  cytoplasm  NLS-bearing protein import into nucleus  ribosomal protein import into nucleus  nuclear localization sequence binding  Ran GTPase binding  protein transporter activity  nuclear membrane  nuclear periphery  
NDEx NetworkTNPO2
Atlas of Cancer Signalling NetworkTNPO2
Wikipedia pathwaysTNPO2
Orthology - Evolution
OrthoDB30000
GeneTree (enSembl)ENSG00000105576
Phylogenetic Trees/Animal Genes : TreeFamTNPO2
HOVERGENO14787
HOGENOMO14787
Homologs : HomoloGeneTNPO2
Homology/Alignments : Family Browser (UCSC)TNPO2
Gene fusions - Rearrangements
Fusion : MitelmanLDLR/TNPO2 [19p13.2/19p13.2]  [t(19;19)(p13;p13)]  
Fusion: TCGALDLR 19p13.2 TNPO2 19p13.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNPO2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNPO2
dbVarTNPO2
ClinVarTNPO2
1000_GenomesTNPO2 
Exome Variant ServerTNPO2
ExAC (Exome Aggregation Consortium)TNPO2 (select the gene name)
Genetic variants : HAPMAP30000
Genomic Variants (DGV)TNPO2 [DGVbeta]
DECIPHER (Syndromes)19:12810008-12834810  ENSG00000105576
CONAN: Copy Number AnalysisTNPO2 
Mutations
ICGC Data PortalTNPO2 
TCGA Data PortalTNPO2 
Broad Tumor PortalTNPO2
OASIS PortalTNPO2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNPO2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNPO2
intOGen PortalTNPO2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNPO2
DgiDB (Drug Gene Interaction Database)TNPO2
DoCM (Curated mutations)TNPO2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNPO2 (select a term)
intoGenTNPO2
Cancer3DTNPO2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603002   
Orphanet
MedgenTNPO2
Genetic Testing Registry TNPO2
NextProtO14787 [Medical]
TSGene30000
GENETestsTNPO2
Huge Navigator TNPO2 [HugePedia]
snp3D : Map Gene to Disease30000
BioCentury BCIQTNPO2
ClinGenTNPO2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD30000
Chemical/Pharm GKB GenePA134921349
Clinical trialTNPO2
Miscellaneous
canSAR (ICR)TNPO2 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNPO2
EVEXTNPO2
GoPubMedTNPO2
iHOPTNPO2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:23:01 CEST 2017

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