Identity
HGNC
LOCATION
19p13.13
LOCUSID
ALIAS
IPO3,KPNB2B,TRN2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 30000
MIM: 603002
HGNC: 19998
Ensembl: ENSG00000105576
Variants:
dbSNP: 30000
ClinVar: 30000
TCGA: ENSG00000105576
COSMIC: TNPO2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34314705 | 2021 | TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila. | 18 |
| 34314705 | 2021 | TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila. | 18 |
| 33122699 | 2020 | Transportin-2 plays a critical role in nucleocytoplasmic shuttling of oestrogen receptor-α. | 5 |
| 33122699 | 2020 | Transportin-2 plays a critical role in nucleocytoplasmic shuttling of oestrogen receptor-α. | 5 |
| 31605449 | 2019 | TNPO2 operates downstream of DYNC1I1 and promotes gastric cancer cell proliferation and inhibits apoptosis. | 8 |
| 31605449 | 2019 | TNPO2 operates downstream of DYNC1I1 and promotes gastric cancer cell proliferation and inhibits apoptosis. | 8 |
| 26060253 | 2015 | IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation. | 13 |
| 26060253 | 2015 | IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation. | 13 |
| 24780099 | 2014 | Transportin-1 and Transportin-2: protein nuclear import and beyond. | 60 |
| 24780099 | 2014 | Transportin-1 and Transportin-2: protein nuclear import and beyond. | 60 |
| 21646354 | 2011 | Transportin 2 regulates apoptosis through the RNA-binding protein HuR. | 11 |
| 21646354 | 2011 | Transportin 2 regulates apoptosis through the RNA-binding protein HuR. | 11 |
| 20606625 | 2010 | ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import. | 417 |
| 20606625 | 2010 | ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import. | 417 |
| 16901787 | 2006 | Rules for nuclear localization sequence recognition by karyopherin beta 2. | 282 |
Citation
Dessen P
TNPO2 (transportin 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-10-01
Online version: http://atlasgeneticsoncology.org/gene/51677/tnpo2
