TNPO2 (transportin 2)

2010-10-01  

Identity

HGNC
LOCATION
19p13.13
LOCUSID
ALIAS
IPO3,KPNB2B,TRN2
FUSION GENES

Other Information

Locus ID:

NCBI: 30000
MIM: 603002
HGNC: 19998
Ensembl: ENSG00000105576

Variants:

dbSNP: 30000
ClinVar: 30000
TCGA: ENSG00000105576
COSMIC: TNPO2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105576ENST00000356861O14787
ENSG00000105576ENST00000356861A0A024R7F7
ENSG00000105576ENST00000425528O14787
ENSG00000105576ENST00000450764O14787
ENSG00000105576ENST00000450764A0A024R7F7
ENSG00000105576ENST00000585886A0A075B780
ENSG00000105576ENST00000586775K7ESC1
ENSG00000105576ENST00000587654K7ESC1
ENSG00000105576ENST00000588216O14787
ENSG00000105576ENST00000588216A0A024R7F7
ENSG00000105576ENST00000588491K7ELC3
ENSG00000105576ENST00000589149K7ESG1
ENSG00000105576ENST00000589337K7ENW1
ENSG00000105576ENST00000589572K7ESJ3
ENSG00000105576ENST00000590781K7EMA3
ENSG00000105576ENST00000592287O14787

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
206066252010ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.282
169017872006Rules for nuclear localization sequence recognition by karyopherin beta 2.209
149812482004Transportin2 functions as importin and mediates nuclear import of HuR.47
247800992014Transportin-1 and Transportin-2: protein nuclear import and beyond.30
123845752002Karyopherin beta 2B participates in mRNA export from the nucleus.10
216463542011Transportin 2 regulates apoptosis through the RNA-binding protein HuR.8
260602532015IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation.7

Citation

Dessen P

TNPO2 (transportin 2)

Atlas Genet Cytogenet Oncol Haematol. 2010-10-01

Online version: http://atlasgeneticsoncology.org/gene/51677/tnpo2