Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TNRC6B (trinucleotide repeat containing 6B)

Identity

Alias_symbol (synonym)KIAA1093
Other alias-
HGNC (Hugo) TNRC6B
LocusID (NCBI) 23112
Atlas_Id 75042
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 40440821 and ends at 40731812 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DSG3 (18q12.1) / TNRC6B (22q13.1)EP300 (22q13.2) / TNRC6B (22q13.1)NXT1 (20p11.21) / TNRC6B (22q13.1)
SGSM3 (22q13.1) / TNRC6B (22q13.1)TNRC6B (22q13.1) / ATXN10 (22q13.31)TNRC6B (22q13.1) / CDH2 (18q12.1)
TNRC6B (22q13.1) / EP300 (22q13.2)TNRC6B (22q13.1) / FAM19A5 (22q13.32)TNRC6B (22q13.1) / STK11 (19p13.3)
TNRC6B (22q13.1) / TMEM184B (22q13.1)TNRC6B (22q13.1) / TNRC6B (22q13.1)TNRC6B (22q13.1) / TP63 (3q28)
TNRC6B (22q13.1) / ZC3H7B (22q13.2)TTC39C (18q11.2) / TNRC6B (22q13.1)TNRC6B EP300
TNRC6B STK11TNRC6B ATXN10EP300 TNRC6B
SGSM3 TNRC6B

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TNRC6B   29190
Cards
Entrez_Gene (NCBI)TNRC6B  23112  trinucleotide repeat containing 6B
Aliases
GeneCards (Weizmann)TNRC6B
Ensembl hg19 (Hinxton)ENSG00000100354 [Gene_View]  chr22:40440821-40731812 [Contig_View]  TNRC6B [Vega]
Ensembl hg38 (Hinxton)ENSG00000100354 [Gene_View]  chr22:40440821-40731812 [Contig_View]  TNRC6B [Vega]
ICGC DataPortalENSG00000100354
TCGA cBioPortalTNRC6B
AceView (NCBI)TNRC6B
Genatlas (Paris)TNRC6B
WikiGenes23112
SOURCE (Princeton)TNRC6B
Genetics Home Reference (NIH)TNRC6B
Genomic and cartography
GoldenPath hg19 (UCSC)TNRC6B  -     chr22:40440821-40731812 +  22q13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TNRC6B  -     22q13.1   [Description]    (hg38-Dec_2013)
EnsemblTNRC6B - 22q13.1 [CytoView hg19]  TNRC6B - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBITNRC6B [Mapview hg19]  TNRC6B [Mapview hg38]
OMIM610740   
Gene and transcription
Genbank (Entrez)AB029016 AK294519 AK296590 AK304087 AL831862
RefSeq transcript (Entrez)NM_001024843 NM_001162501 NM_015088
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)TNRC6B
Cluster EST : UnigeneHs.372082 [ NCBI ]
CGAP (NCI)Hs.372082
Alternative Splicing GalleryENSG00000100354
Gene ExpressionTNRC6B [ NCBI-GEO ]   TNRC6B [ EBI - ARRAY_EXPRESS ]   TNRC6B [ SEEK ]   TNRC6B [ MEM ]
Gene Expression Viewer (FireBrowse)TNRC6B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23112
GTEX Portal (Tissue expression)TNRC6B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPQ9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPQ9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPQ9
Splice isoforms : SwissVarQ9UPQ9
PhosPhoSitePlusQ9UPQ9
Domains : Interpro (EBI)Argonaute_hook_dom    Nucleotide-bd_a/b_plait   
Domain families : Pfam (Sanger)Ago_hook (PF10427)   
Domain families : Pfam (NCBI)pfam10427   
Conserved Domain (NCBI)TNRC6B
DMDM Disease mutations23112
Blocks (Seattle)TNRC6B
SuperfamilyQ9UPQ9
Human Protein AtlasENSG00000100354
Peptide AtlasQ9UPQ9
IPIIPI00152296   IPI00940033   IPI00385511   IPI00908413   IPI00873067   IPI00878874   
Protein Interaction databases
DIP (DOE-UCLA)Q9UPQ9
IntAct (EBI)Q9UPQ9
FunCoupENSG00000100354
BioGRIDTNRC6B
STRING (EMBL)TNRC6B
ZODIACTNRC6B
Ontologies - Pathways
QuickGOQ9UPQ9
Ontology : AmiGOnucleotide binding  cytoplasmic mRNA processing body  protein binding  cytosol  regulation of translation  epidermal growth factor receptor signaling pathway  Notch signaling pathway  fibroblast growth factor receptor signaling pathway  gene expression  posttranscriptional gene silencing  gene silencing by RNA  Fc-epsilon receptor signaling pathway  poly(A) RNA binding  innate immune response  neurotrophin TRK receptor signaling pathway  phosphatidylinositol-mediated signaling  positive regulation of nuclear-transcribed mRNA poly(A) tail shortening  positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  
Ontology : EGO-EBInucleotide binding  cytoplasmic mRNA processing body  protein binding  cytosol  regulation of translation  epidermal growth factor receptor signaling pathway  Notch signaling pathway  fibroblast growth factor receptor signaling pathway  gene expression  posttranscriptional gene silencing  gene silencing by RNA  Fc-epsilon receptor signaling pathway  poly(A) RNA binding  innate immune response  neurotrophin TRK receptor signaling pathway  phosphatidylinositol-mediated signaling  positive regulation of nuclear-transcribed mRNA poly(A) tail shortening  positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  
NDEx NetworkTNRC6B
Atlas of Cancer Signalling NetworkTNRC6B
Wikipedia pathwaysTNRC6B
Orthology - Evolution
OrthoDB23112
GeneTree (enSembl)ENSG00000100354
Phylogenetic Trees/Animal Genes : TreeFamTNRC6B
HOVERGENQ9UPQ9
HOGENOMQ9UPQ9
Homologs : HomoloGeneTNRC6B
Homology/Alignments : Family Browser (UCSC)TNRC6B
Gene fusions - Rearrangements
Fusion: TCGATNRC6B EP300
Fusion: TCGATNRC6B STK11
Fusion: TCGATNRC6B ATXN10
Fusion: TCGAEP300 TNRC6B
Fusion: TCGASGSM3 TNRC6B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTNRC6B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TNRC6B
dbVarTNRC6B
ClinVarTNRC6B
1000_GenomesTNRC6B 
Exome Variant ServerTNRC6B
ExAC (Exome Aggregation Consortium)TNRC6B (select the gene name)
Genetic variants : HAPMAP23112
Genomic Variants (DGV)TNRC6B [DGVbeta]
DECIPHER (Syndromes)22:40440821-40731812  ENSG00000100354
CONAN: Copy Number AnalysisTNRC6B 
Mutations
ICGC Data PortalTNRC6B 
TCGA Data PortalTNRC6B 
Broad Tumor PortalTNRC6B
OASIS PortalTNRC6B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTNRC6B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTNRC6B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TNRC6B
DgiDB (Drug Gene Interaction Database)TNRC6B
DoCM (Curated mutations)TNRC6B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TNRC6B (select a term)
intoGenTNRC6B
Cancer3DTNRC6B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610740   
Orphanet
MedgenTNRC6B
Genetic Testing Registry TNRC6B
NextProtQ9UPQ9 [Medical]
TSGene23112
GENETestsTNRC6B
Huge Navigator TNRC6B [HugePedia]
snp3D : Map Gene to Disease23112
BioCentury BCIQTNRC6B
ClinGenTNRC6B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23112
Chemical/Pharm GKB GenePA134992981
Clinical trialTNRC6B
Miscellaneous
canSAR (ICR)TNRC6B (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTNRC6B
EVEXTNRC6B
GoPubMedTNRC6B
iHOPTNRC6B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:49:16 CET 2017

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