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TOM1L2 (target of myb1 like 2 membrane trafficking protein)

Identity

Alias (NCBI)-
HGNC (Hugo) TOM1L2
HGNC Previous nametarget of myb1 (chicken) homolog-like 1
 target of myb1-like 2 (chicken)
LocusID (NCBI) 146691
Atlas_Id 75050
Location 17p11.2  [Link to chromosome band 17p11]
Location_base_pair Starts at 17843511 and ends at 17972400 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SREBF1 (17p11.2) / TOM1L2 (17p11.2)SYMPK (19q13.32) / TOM1L2 (17p11.2)TOM1L2 (17p11.2) / AC005863.1 ()
TOM1L2 (17p11.2) / ATPAF2 (17p11.2)TOM1L2 (17p11.2) / NECAB2 (16q23.3)TOM1L2 (17p11.2) / RBM26 (13q31.1)
TOM1L2 (17p11.2) / ULK2 (17p11.2)TTC19 (17p12) / TOM1L2 (17p11.2)TTF1 (9q34.13) / TOM1L2 (17p11.2)
TOM1L2 AC005863.1TOM1L2 ULK2TOM1L2 ATPAF2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TOM1L2   11984
Cards
Entrez_Gene (NCBI)TOM1L2    target of myb1 like 2 membrane trafficking protein
Aliases
GeneCards (Weizmann)TOM1L2
Ensembl hg19 (Hinxton)ENSG00000175662 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175662 [Gene_View]  ENSG00000175662 [Sequence]  chr17:17843511-17972400 [Contig_View]  TOM1L2 [Vega]
ICGC DataPortalENSG00000175662
TCGA cBioPortalTOM1L2
AceView (NCBI)TOM1L2
Genatlas (Paris)TOM1L2
SOURCE (Princeton)TOM1L2
Genetics Home Reference (NIH)TOM1L2
Genomic and cartography
GoldenPath hg38 (UCSC)TOM1L2  -     chr17:17843511-17972400 -  17p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TOM1L2  -     17p11.2   [Description]    (hg19-Feb_2009)
GoldenPathTOM1L2 - 17p11.2 [CytoView hg19]  TOM1L2 - 17p11.2 [CytoView hg38]
ImmunoBaseENSG00000175662
Genome Data Viewer NCBITOM1L2 [Mapview hg19]  
OMIM615519   
Gene and transcription
Genbank (Entrez)AF038192 AF467441 AK025154 AK055959 AK057308
RefSeq transcript (Entrez)NM_001033551 NM_001082968 NM_001288786 NM_001288787 NM_001288788 NM_001288789 NM_001350331 NM_001350332 NM_001350333 NM_144678
Consensus coding sequences : CCDS (NCBI)TOM1L2
Gene ExpressionTOM1L2 [ NCBI-GEO ]   TOM1L2 [ EBI - ARRAY_EXPRESS ]   TOM1L2 [ SEEK ]   TOM1L2 [ MEM ]
Gene Expression Viewer (FireBrowse)TOM1L2 [ Firebrowse - Broad ]
GenevisibleExpression of TOM1L2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)146691
GTEX Portal (Tissue expression)TOM1L2
Human Protein AtlasENSG00000175662-TOM1L2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZVM7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZVM7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZVM7
PhosPhoSitePlusQ6ZVM7
Domaine pattern : Prosite (Expaxy)GAT (PS50909)    VHS (PS50179)   
Domains : Interpro (EBI)ENTH_VHS    GAT_dom    GAT_sf    TOM1    TOM1L2    VHS_dom   
Domain families : Pfam (Sanger)GAT (PF03127)    VHS (PF00790)   
Domain families : Pfam (NCBI)pfam03127    pfam00790   
Domain families : Smart (EMBL)VHS (SM00288)  
Conserved Domain (NCBI)TOM1L2
SuperfamilyQ6ZVM7
AlphaFold pdb e-kbQ6ZVM7   
Human Protein Atlas [tissue]ENSG00000175662-TOM1L2 [tissue]
HPRD18213
Protein Interaction databases
DIP (DOE-UCLA)Q6ZVM7
IntAct (EBI)Q6ZVM7
BioGRIDTOM1L2
STRING (EMBL)TOM1L2
ZODIACTOM1L2
Ontologies - Pathways
QuickGOQ6ZVM7
Ontology : AmiGOprotein binding  endosome  signal transduction  signal transduction  protein transport  membrane  protein kinase binding  clathrin binding  clathrin binding  phosphatidylinositol binding  ubiquitin binding  negative regulation of mitotic nuclear division  extracellular exosome  
Ontology : EGO-EBIprotein binding  endosome  signal transduction  signal transduction  protein transport  membrane  protein kinase binding  clathrin binding  clathrin binding  phosphatidylinositol binding  ubiquitin binding  negative regulation of mitotic nuclear division  extracellular exosome  
NDEx NetworkTOM1L2
Atlas of Cancer Signalling NetworkTOM1L2
Wikipedia pathwaysTOM1L2
Orthology - Evolution
OrthoDB146691
GeneTree (enSembl)ENSG00000175662
Phylogenetic Trees/Animal Genes : TreeFamTOM1L2
Homologs : HomoloGeneTOM1L2
Homology/Alignments : Family Browser (UCSC)TOM1L2
Gene fusions - Rearrangements
Fusion : QuiverTOM1L2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTOM1L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TOM1L2
dbVarTOM1L2
ClinVarTOM1L2
MonarchTOM1L2
1000_GenomesTOM1L2 
Exome Variant ServerTOM1L2
GNOMAD BrowserENSG00000175662
Varsome BrowserTOM1L2
ACMGTOM1L2 variants
VarityQ6ZVM7
Genomic Variants (DGV)TOM1L2 [DGVbeta]
DECIPHERTOM1L2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTOM1L2 
Mutations
ICGC Data PortalTOM1L2 
TCGA Data PortalTOM1L2 
Broad Tumor PortalTOM1L2
OASIS PortalTOM1L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTOM1L2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTOM1L2
Mutations and Diseases : HGMDTOM1L2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTOM1L2
DgiDB (Drug Gene Interaction Database)TOM1L2
DoCM (Curated mutations)TOM1L2
CIViC (Clinical Interpretations of Variants in Cancer)TOM1L2
Cancer3DTOM1L2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615519   
Orphanet
DisGeNETTOM1L2
MedgenTOM1L2
Genetic Testing Registry TOM1L2
NextProtQ6ZVM7 [Medical]
GENETestsTOM1L2
Target ValidationTOM1L2
Huge Navigator TOM1L2 [HugePedia]
ClinGenTOM1L2
Clinical trials, drugs, therapy
MyCancerGenomeTOM1L2
Protein Interactions : CTDTOM1L2
Pharm GKB GenePA36668
PharosQ6ZVM7
Clinical trialTOM1L2
Miscellaneous
canSAR (ICR)TOM1L2
HarmonizomeTOM1L2
DataMed IndexTOM1L2
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTOM1L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:26:32 CEST 2021

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