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TOM1L2 (target of myb1-like 2 (chicken))

Identity

Alias_namestarget of myb1 (chicken) homolog-like 1
target of myb1-like 2 (chicken)
Other alias-
HGNC (Hugo) TOM1L2
LocusID (NCBI) 146691
Atlas_Id 75050
Location 17p11.2  [Link to chromosome band 17p11]
Location_base_pair Starts at 17746822 and ends at 17875784 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SREBF1 (17p11.2) / TOM1L2 (17p11.2)SYMPK (19q13.32) / TOM1L2 (17p11.2)TOM1L2 (17p11.2) / AC005863.1 ()
TOM1L2 (17p11.2) / ATPAF2 (17p11.2)TOM1L2 (17p11.2) / NECAB2 (16q23.3)TOM1L2 (17p11.2) / RBM26 (13q31.1)
TOM1L2 (17p11.2) / ULK2 (17p11.2)TTC19 (17p12) / TOM1L2 (17p11.2)TTF1 (9q34.13) / TOM1L2 (17p11.2)
TOM1L2 AC005863.1TOM1L2 ULK2TOM1L2 ATPAF2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TOM1L2   11984
Cards
Entrez_Gene (NCBI)TOM1L2  146691  target of myb1-like 2 (chicken)
Aliases
GeneCards (Weizmann)TOM1L2
Ensembl hg19 (Hinxton)ENSG00000175662 [Gene_View]  chr17:17746822-17875784 [Contig_View]  TOM1L2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000175662 [Gene_View]  chr17:17746822-17875784 [Contig_View]  TOM1L2 [Vega]
ICGC DataPortalENSG00000175662
TCGA cBioPortalTOM1L2
AceView (NCBI)TOM1L2
Genatlas (Paris)TOM1L2
WikiGenes146691
SOURCE (Princeton)TOM1L2
Genetics Home Reference (NIH)TOM1L2
Genomic and cartography
GoldenPath hg19 (UCSC)TOM1L2  -     chr17:17746822-17875784 -  17p11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TOM1L2  -     17p11.2   [Description]    (hg38-Dec_2013)
EnsemblTOM1L2 - 17p11.2 [CytoView hg19]  TOM1L2 - 17p11.2 [CytoView hg38]
Mapping of homologs : NCBITOM1L2 [Mapview hg19]  TOM1L2 [Mapview hg38]
OMIM615519   
Gene and transcription
Genbank (Entrez)AF038192 AF467441 AK025154 AK055959 AK057308
RefSeq transcript (Entrez)NM_001033551 NM_001082968 NM_001288786 NM_001288787 NM_001288788 NM_001288789 NM_144678
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010718 NW_004929405
Consensus coding sequences : CCDS (NCBI)TOM1L2
Cluster EST : UnigeneHs.462379 [ NCBI ]
CGAP (NCI)Hs.462379
Alternative Splicing GalleryENSG00000175662
Gene ExpressionTOM1L2 [ NCBI-GEO ]   TOM1L2 [ EBI - ARRAY_EXPRESS ]   TOM1L2 [ SEEK ]   TOM1L2 [ MEM ]
Gene Expression Viewer (FireBrowse)TOM1L2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)146691
GTEX Portal (Tissue expression)TOM1L2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZVM7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZVM7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZVM7
Splice isoforms : SwissVarQ6ZVM7
PhosPhoSitePlusQ6ZVM7
Domaine pattern : Prosite (Expaxy)GAT (PS50909)    VHS (PS50179)   
Domains : Interpro (EBI)ENTH_VHS    GAT_dom    TOM1    TOM1L2    VHS    VHS_subgr   
Domain families : Pfam (Sanger)GAT (PF03127)    VHS (PF00790)   
Domain families : Pfam (NCBI)pfam03127    pfam00790   
Domain families : Smart (EMBL)VHS (SM00288)  
Conserved Domain (NCBI)TOM1L2
DMDM Disease mutations146691
Blocks (Seattle)TOM1L2
SuperfamilyQ6ZVM7
Human Protein AtlasENSG00000175662
Peptide AtlasQ6ZVM7
HPRD18213
IPIIPI00446294   IPI00651745   IPI00328178   IPI00828126   IPI00921925   IPI00922748   IPI00922013   IPI00922594   IPI00432276   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZVM7
IntAct (EBI)Q6ZVM7
FunCoupENSG00000175662
BioGRIDTOM1L2
STRING (EMBL)TOM1L2
ZODIACTOM1L2
Ontologies - Pathways
QuickGOQ6ZVM7
Ontology : AmiGOprotein binding  intracellular  intracellular protein transport  signal transduction  protein kinase binding  clathrin binding  negative regulation of mitotic nuclear division  extracellular exosome  
Ontology : EGO-EBIprotein binding  intracellular  intracellular protein transport  signal transduction  protein kinase binding  clathrin binding  negative regulation of mitotic nuclear division  extracellular exosome  
NDEx NetworkTOM1L2
Atlas of Cancer Signalling NetworkTOM1L2
Wikipedia pathwaysTOM1L2
Orthology - Evolution
OrthoDB146691
GeneTree (enSembl)ENSG00000175662
Phylogenetic Trees/Animal Genes : TreeFamTOM1L2
HOVERGENQ6ZVM7
HOGENOMQ6ZVM7
Homologs : HomoloGeneTOM1L2
Homology/Alignments : Family Browser (UCSC)TOM1L2
Gene fusions - Rearrangements
Fusion: TCGATOM1L2 AC005863.1
Fusion: TCGATOM1L2 ULK2
Fusion: TCGATOM1L2 ATPAF2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTOM1L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TOM1L2
dbVarTOM1L2
ClinVarTOM1L2
1000_GenomesTOM1L2 
Exome Variant ServerTOM1L2
ExAC (Exome Aggregation Consortium)TOM1L2 (select the gene name)
Genetic variants : HAPMAP146691
Genomic Variants (DGV)TOM1L2 [DGVbeta]
DECIPHER (Syndromes)17:17746822-17875784  ENSG00000175662
CONAN: Copy Number AnalysisTOM1L2 
Mutations
ICGC Data PortalTOM1L2 
TCGA Data PortalTOM1L2 
Broad Tumor PortalTOM1L2
OASIS PortalTOM1L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTOM1L2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTOM1L2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TOM1L2
DgiDB (Drug Gene Interaction Database)TOM1L2
DoCM (Curated mutations)TOM1L2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TOM1L2 (select a term)
intoGenTOM1L2
Cancer3DTOM1L2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615519   
Orphanet
MedgenTOM1L2
Genetic Testing Registry TOM1L2
NextProtQ6ZVM7 [Medical]
TSGene146691
GENETestsTOM1L2
Huge Navigator TOM1L2 [HugePedia]
snp3D : Map Gene to Disease146691
BioCentury BCIQTOM1L2
ClinGenTOM1L2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD146691
Chemical/Pharm GKB GenePA36668
Clinical trialTOM1L2
Miscellaneous
canSAR (ICR)TOM1L2 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTOM1L2
EVEXTOM1L2
GoPubMedTOM1L2
iHOPTOM1L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:49:18 CET 2017

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