TOMM7 (translocase of outer mitochondrial membrane 7)

2014-11-01  

Identity

HGNC
TOMM7
LOCATION
7p15.3
LOCUSID
54543
ALIAS
TOM7
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54543
MIM: 607980
HGNC: 21648
Ensembl: ENSG00000196683

Variants:

dbSNP: 54543
ClinVar: 54543
TCGA: ENSG00000196683
COSMIC: TOMM7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196683ENST00000358435Q9P0U1
ENSG00000196683ENST00000358435Q75MR5
ENSG00000196683ENST00000372879A6NIV2
ENSG00000196683ENST00000405021B5MD00
ENSG00000196683ENST00000621567A0A087WZY2

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Mitochondrial protein importREACTOMER-HSA-1268020
MitophagyREACTOMER-HSA-5205647
Pink/Parkin Mediated MitophagyREACTOMER-HSA-5205685
Mitophagy - animalKEGGko04137
Mitophagy - animalKEGGhsa04137

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
121981232002Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane.37
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
183318222008Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane.13
307331182019Reciprocal Roles of Tom7 and OMA1 during Mitochondrial Import and Activation of PINK1.9

Citation

Dessen P

TOMM7 (translocase of outer mitochondrial membrane 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75055/tomm7