Identity |
Alias (NCBI) | TOP2 | TP2A |
HGNC (Hugo) | TOP2A |
HGNC Previous name | TOP2 |
HGNC Previous name | topoisomerase (DNA) II alpha 170kDa |
LocusID (NCBI) | 7153 |
Atlas_Id | 42659 |
Location | 17q21.2 [Link to chromosome band 17q21] |
Location_base_pair | Starts at 40388525 and ends at 40417896 bp from pter ( according to hg38-Dec_2013) |
Fusion genes (updated 2017) | Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands) |
C17orf75 (17q11.2) / TOP2A (17q21.2) | EZH1 (17q21.2) / TOP2A (17q21.2) | ILF3 (19p13.2) / TOP2A (17q21.2) | |
RBM17 (10p15.1) / TOP2A (17q21.2) | C17orf75 17q11.2 / TOP2A 17q21.2 | EZH1 17q21.2 / TOP2A 17q21.2 | |
Note | Non-annotated gene. Preliminary data : if you are an author |
DNA/RNA |
Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 5 ] |
Thyroid: Anaplastic (undifferentiated) carcinoma
Breast: Ductal carcinoma Nervous System: Optic nerve glioma t(17;17)(q11;q21) C17orf75/TOP2A EZH1/TOP2A (17q21) |
External links |
Genes in title | automatic search in PubMed |
REVIEW articles | automatic search in PubMed |
Last year publications | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Fri Jan 1 18:41:57 CET 2021 |
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