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TOPAZ1 (testis and ovary specific PAZ domain containing 1)

Identity

Alias_namesC3orf77
chromosome 3 open reading frame 77
Alias_symbol (synonym)FLJ36157
Other alias
HGNC (Hugo) TOPAZ1
LocusID (NCBI) 375337
Atlas_Id 75058
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 44241886 and ends at 44332098 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TOPAZ1   24746
Cards
Entrez_Gene (NCBI)TOPAZ1  375337  testis and ovary specific PAZ domain containing 1
AliasesC3orf77
GeneCards (Weizmann)TOPAZ1
Ensembl hg19 (Hinxton)ENSG00000173769 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173769 [Gene_View]  chr3:44241886-44332098 [Contig_View]  TOPAZ1 [Vega]
ICGC DataPortalENSG00000173769
TCGA cBioPortalTOPAZ1
AceView (NCBI)TOPAZ1
Genatlas (Paris)TOPAZ1
WikiGenes375337
SOURCE (Princeton)TOPAZ1
Genetics Home Reference (NIH)TOPAZ1
Genomic and cartography
GoldenPath hg38 (UCSC)TOPAZ1  -     chr3:44241886-44332098 +  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TOPAZ1  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblTOPAZ1 - 3p21.31 [CytoView hg19]  TOPAZ1 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBITOPAZ1 [Mapview hg19]  TOPAZ1 [Mapview hg38]
OMIM614412   
Gene and transcription
Genbank (Entrez)AK093476 BX648094
RefSeq transcript (Entrez)NM_001145030
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TOPAZ1
Cluster EST : UnigeneHs.132125 [ NCBI ]
CGAP (NCI)Hs.132125
Alternative Splicing GalleryENSG00000173769
Gene ExpressionTOPAZ1 [ NCBI-GEO ]   TOPAZ1 [ EBI - ARRAY_EXPRESS ]   TOPAZ1 [ SEEK ]   TOPAZ1 [ MEM ]
Gene Expression Viewer (FireBrowse)TOPAZ1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)375337
GTEX Portal (Tissue expression)TOPAZ1
Human Protein AtlasENSG00000173769-TOPAZ1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N9V7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N9V7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N9V7
Splice isoforms : SwissVarQ8N9V7
PhosPhoSitePlusQ8N9V7
Domains : Interpro (EBI)TOPAZ1   
Domain families : Pfam (Sanger)Asp_Glu_race_2 (PF14669)   
Domain families : Pfam (NCBI)pfam14669   
Conserved Domain (NCBI)TOPAZ1
DMDM Disease mutations375337
Blocks (Seattle)TOPAZ1
SuperfamilyQ8N9V7
Human Protein Atlas [tissue]ENSG00000173769-TOPAZ1 [tissue]
Peptide AtlasQ8N9V7
IPIIPI00885176   IPI00979376   
Protein Interaction databases
DIP (DOE-UCLA)Q8N9V7
IntAct (EBI)Q8N9V7
FunCoupENSG00000173769
BioGRIDTOPAZ1
STRING (EMBL)TOPAZ1
ZODIACTOPAZ1
Ontologies - Pathways
QuickGOQ8N9V7
Ontology : AmiGOcytosol  apoptotic process  spermatid development  metal ion binding  spermatocyte division  ncRNA transcription  positive regulation of meiotic cell cycle phase transition  
Ontology : EGO-EBIcytosol  apoptotic process  spermatid development  metal ion binding  spermatocyte division  ncRNA transcription  positive regulation of meiotic cell cycle phase transition  
NDEx NetworkTOPAZ1
Atlas of Cancer Signalling NetworkTOPAZ1
Wikipedia pathwaysTOPAZ1
Orthology - Evolution
OrthoDB375337
GeneTree (enSembl)ENSG00000173769
Phylogenetic Trees/Animal Genes : TreeFamTOPAZ1
HOVERGENQ8N9V7
HOGENOMQ8N9V7
Homologs : HomoloGeneTOPAZ1
Homology/Alignments : Family Browser (UCSC)TOPAZ1
Gene fusions - Rearrangements
Tumor Fusion PortalTOPAZ1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTOPAZ1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TOPAZ1
dbVarTOPAZ1
ClinVarTOPAZ1
1000_GenomesTOPAZ1 
Exome Variant ServerTOPAZ1
ExAC (Exome Aggregation Consortium)ENSG00000173769
GNOMAD BrowserENSG00000173769
Genetic variants : HAPMAP375337
Genomic Variants (DGV)TOPAZ1 [DGVbeta]
DECIPHERTOPAZ1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTOPAZ1 
Mutations
ICGC Data PortalTOPAZ1 
TCGA Data PortalTOPAZ1 
Broad Tumor PortalTOPAZ1
OASIS PortalTOPAZ1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDTOPAZ1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TOPAZ1
DgiDB (Drug Gene Interaction Database)TOPAZ1
DoCM (Curated mutations)TOPAZ1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TOPAZ1 (select a term)
intoGenTOPAZ1
Cancer3DTOPAZ1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614412   
Orphanet
DisGeNETTOPAZ1
MedgenTOPAZ1
Genetic Testing Registry TOPAZ1
NextProtQ8N9V7 [Medical]
TSGene375337
GENETestsTOPAZ1
Target ValidationTOPAZ1
Huge Navigator TOPAZ1 [HugePedia]
snp3D : Map Gene to Disease375337
BioCentury BCIQTOPAZ1
ClinGenTOPAZ1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD375337
Chemical/Pharm GKB GenePA165696874
Clinical trialTOPAZ1
Miscellaneous
canSAR (ICR)TOPAZ1 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTOPAZ1
EVEXTOPAZ1
GoPubMedTOPAZ1
iHOPTOPAZ1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:09:18 CET 2017

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