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TOX (thymocyte selection associated high mobility group box)

Identity

Alias_symbol (synonym)KIAA0808
TOX1
Other alias
HGNC (Hugo) TOX
LocusID (NCBI) 9760
Atlas_Id 47116
Location 8q12.1  [Link to chromosome band 8q12]
Location_base_pair Starts at 58805418 and ends at 59119208 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CHD7 (8q12.2) / TOX (8q12.1)TOX (8q12.1) / CHD7 (8q12.2)TOX (8q12.1) / PGBD2 (1q44)
TOX (8q12.1) / ZNF543 (19q13.43)CHD7 8q12.1 / TOX 8q12.1TOX 8q12.1 / PGBD2 1q44

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TOX   18988
Cards
Entrez_Gene (NCBI)TOX  9760  thymocyte selection associated high mobility group box
AliasesTOX1
GeneCards (Weizmann)TOX
Ensembl hg19 (Hinxton)ENSG00000198846 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198846 [Gene_View]  chr8:58805418-59119208 [Contig_View]  TOX [Vega]
ICGC DataPortalENSG00000198846
TCGA cBioPortalTOX
AceView (NCBI)TOX
Genatlas (Paris)TOX
WikiGenes9760
SOURCE (Princeton)TOX
Genetics Home Reference (NIH)TOX
Genomic and cartography
GoldenPath hg38 (UCSC)TOX  -     chr8:58805418-59119208 -  8q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TOX  -     8q12.1   [Description]    (hg19-Feb_2009)
EnsemblTOX - 8q12.1 [CytoView hg19]  TOX - 8q12.1 [CytoView hg38]
Mapping of homologs : NCBITOX [Mapview hg19]  TOX [Mapview hg38]
OMIM606863   
Gene and transcription
Genbank (Entrez)AB018351 AK000971 AK302331 BC016665 BX647462
RefSeq transcript (Entrez)NM_014729
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TOX
Cluster EST : UnigeneHs.634856 [ NCBI ]
CGAP (NCI)Hs.634856
Alternative Splicing GalleryENSG00000198846
Gene ExpressionTOX [ NCBI-GEO ]   TOX [ EBI - ARRAY_EXPRESS ]   TOX [ SEEK ]   TOX [ MEM ]
Gene Expression Viewer (FireBrowse)TOX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9760
GTEX Portal (Tissue expression)TOX
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94900   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94900  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94900
Splice isoforms : SwissVarO94900
PhosPhoSitePlusO94900
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)HMG_box_dom   
Domain families : Pfam (Sanger)HMG_box (PF00505)   
Domain families : Pfam (NCBI)pfam00505   
Domain families : Smart (EMBL)HMG (SM00398)  
Conserved Domain (NCBI)TOX
DMDM Disease mutations9760
Blocks (Seattle)TOX
SuperfamilyO94900
Human Protein AtlasENSG00000198846
Peptide AtlasO94900
HPRD12113
IPIIPI00006065   IPI00903214   IPI01009599   
Protein Interaction databases
DIP (DOE-UCLA)O94900
IntAct (EBI)O94900
FunCoupENSG00000198846
BioGRIDTOX
STRING (EMBL)TOX
ZODIACTOX
Ontologies - Pathways
QuickGOO94900
Ontology : AmiGODNA binding  nucleus  
Ontology : EGO-EBIDNA binding  nucleus  
NDEx NetworkTOX
Atlas of Cancer Signalling NetworkTOX
Wikipedia pathwaysTOX
Orthology - Evolution
OrthoDB9760
GeneTree (enSembl)ENSG00000198846
Phylogenetic Trees/Animal Genes : TreeFamTOX
HOVERGENO94900
HOGENOMO94900
Homologs : HomoloGeneTOX
Homology/Alignments : Family Browser (UCSC)TOX
Gene fusions - Rearrangements
Fusion : MitelmanCHD7/TOX [8q12.1/8q12.1]  [t(8;8)(q12;q12)]  
Fusion : MitelmanTOX/PGBD2 [8q12.1/1q44]  [t(1;8)(q44;q12)]  
Fusion: TCGACHD7 8q12.1 TOX 8q12.1 GBM
Fusion: TCGATOX 8q12.1 PGBD2 1q44 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTOX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TOX
dbVarTOX
ClinVarTOX
1000_GenomesTOX 
Exome Variant ServerTOX
ExAC (Exome Aggregation Consortium)TOX (select the gene name)
Genetic variants : HAPMAP9760
Genomic Variants (DGV)TOX [DGVbeta]
DECIPHERTOX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTOX 
Mutations
ICGC Data PortalTOX 
TCGA Data PortalTOX 
Broad Tumor PortalTOX
OASIS PortalTOX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTOX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTOX
LOVD (Leiden Open Variation Database)The Globin Gene Server
BioMutasearch TOX
DgiDB (Drug Gene Interaction Database)TOX
DoCM (Curated mutations)TOX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TOX (select a term)
intoGenTOX
Cancer3DTOX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606863   
Orphanet
MedgenTOX
Genetic Testing Registry TOX
NextProtO94900 [Medical]
TSGene9760
GENETestsTOX
Target ValidationTOX
Huge Navigator TOX [HugePedia]
snp3D : Map Gene to Disease9760
BioCentury BCIQTOX
ClinGenTOX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9760
Chemical/Pharm GKB GenePA162406704
Clinical trialTOX
Miscellaneous
canSAR (ICR)TOX (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTOX
EVEXTOX
GoPubMedTOX
iHOPTOX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:17:26 CEST 2017

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