Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TOX2 (TOX high mobility group box family member 2)

Identity

Alias (NCBI)C20orf100
GCX-1
GCX1
dJ1108D11.2
dJ495O3.1
HGNC (Hugo) TOX2
HGNC Alias symbdJ1108D11.2
GCX-1
HGNC Alias namegranulosa cell HMG box 1
HGNC Previous nameC20orf100
HGNC Previous namechromosome 20 open reading frame 100
LocusID (NCBI) 84969
Atlas_Id 52854
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 43916130 and ends at 44069614 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
B4GALT5 (20q13.13) / TOX2 (20q13.12)EEF1G (11q12.3) / TOX2 (20q13.12)TRPC4AP (20q11.22) / TOX2 (20q13.12)
B4GALT5 20q13.13 / TOX2 20q13.12TRPC4AP 20q11.22 / TOX2 20q13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TOX2   16095
Cards
Entrez_Gene (NCBI)TOX2    TOX high mobility group box family member 2
AliasesC20orf100; GCX-1; GCX1; dJ1108D11.2; 
dJ495O3.1
GeneCards (Weizmann)TOX2
Ensembl hg19 (Hinxton)ENSG00000124191 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124191 [Gene_View]  ENSG00000124191 [Sequence]  chr20:43916130-44069614 [Contig_View]  TOX2 [Vega]
ICGC DataPortalENSG00000124191
TCGA cBioPortalTOX2
AceView (NCBI)TOX2
Genatlas (Paris)TOX2
SOURCE (Princeton)TOX2
Genetics Home Reference (NIH)TOX2
Genomic and cartography
GoldenPath hg38 (UCSC)TOX2  -     chr20:43916130-44069614 +  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TOX2  -     20q13.12   [Description]    (hg19-Feb_2009)
GoldenPathTOX2 - 20q13.12 [CytoView hg19]  TOX2 - 20q13.12 [CytoView hg38]
ImmunoBaseENSG00000124191
Genome Data Viewer NCBITOX2 [Mapview hg19]  
OMIM611163   
Gene and transcription
Genbank (Entrez)AK055135 AK289906 AK298976 BC007636 BM545579
RefSeq transcript (Entrez)NM_001098796 NM_001098797 NM_001098798 NM_032883
Consensus coding sequences : CCDS (NCBI)TOX2
Gene ExpressionTOX2 [ NCBI-GEO ]   TOX2 [ EBI - ARRAY_EXPRESS ]   TOX2 [ SEEK ]   TOX2 [ MEM ]
Gene Expression Viewer (FireBrowse)TOX2 [ Firebrowse - Broad ]
GenevisibleExpression of TOX2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84969
GTEX Portal (Tissue expression)TOX2
Human Protein AtlasENSG00000124191-TOX2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96NM4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96NM4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96NM4
PhosPhoSitePlusQ96NM4
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)HMG_box_dom    HMG_box_dom_sf   
Domain families : Pfam (Sanger)HMG_box (PF00505)   
Domain families : Pfam (NCBI)pfam00505   
Domain families : Smart (EMBL)HMG (SM00398)  
Conserved Domain (NCBI)TOX2
SuperfamilyQ96NM4
AlphaFold pdb e-kbQ96NM4   
Human Protein Atlas [tissue]ENSG00000124191-TOX2 [tissue]
HPRD12734
Protein Interaction databases
DIP (DOE-UCLA)Q96NM4
IntAct (EBI)Q96NM4
BioGRIDTOX2
STRING (EMBL)TOX2
ZODIACTOX2
Ontologies - Pathways
QuickGOQ96NM4
Ontology : AmiGOtranscription coactivator activity  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  chromatin DNA binding  positive regulation of transcription by RNA polymerase II  
Ontology : EGO-EBItranscription coactivator activity  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  chromatin DNA binding  positive regulation of transcription by RNA polymerase II  
NDEx NetworkTOX2
Atlas of Cancer Signalling NetworkTOX2
Wikipedia pathwaysTOX2
Orthology - Evolution
OrthoDB84969
GeneTree (enSembl)ENSG00000124191
Phylogenetic Trees/Animal Genes : TreeFamTOX2
Homologs : HomoloGeneTOX2
Homology/Alignments : Family Browser (UCSC)TOX2
Gene fusions - Rearrangements
Fusion : MitelmanB4GALT5/TOX2 [20q13.13/20q13.12]  
Fusion : MitelmanTRPC4AP/TOX2 [20q11.22/20q13.12]  
Fusion : QuiverTOX2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTOX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TOX2
dbVarTOX2
ClinVarTOX2
MonarchTOX2
1000_GenomesTOX2 
Exome Variant ServerTOX2
GNOMAD BrowserENSG00000124191
Varsome BrowserTOX2
ACMGTOX2 variants
VarityQ96NM4
Genomic Variants (DGV)TOX2 [DGVbeta]
DECIPHERTOX2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTOX2 
Mutations
ICGC Data PortalTOX2 
TCGA Data PortalTOX2 
Broad Tumor PortalTOX2
OASIS PortalTOX2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTOX2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTOX2
Mutations and Diseases : HGMDTOX2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTOX2
DgiDB (Drug Gene Interaction Database)TOX2
DoCM (Curated mutations)TOX2
CIViC (Clinical Interpretations of Variants in Cancer)TOX2
Cancer3DTOX2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611163   
Orphanet
DisGeNETTOX2
MedgenTOX2
Genetic Testing Registry TOX2
NextProtQ96NM4 [Medical]
GENETestsTOX2
Target ValidationTOX2
Huge Navigator TOX2 [HugePedia]
ClinGenTOX2
Clinical trials, drugs, therapy
MyCancerGenomeTOX2
Protein Interactions : CTDTOX2
Pharm GKB GenePA162406727
PharosQ96NM4
Clinical trialTOX2
Miscellaneous
canSAR (ICR)TOX2
HarmonizomeTOX2
DataMed IndexTOX2
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTOX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:35:56 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.