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TOX4 (TOX high mobility group box family member 4)

Identity

Alias_namesC14orf92
KIAA0737
chromosome 14 open reading frame 92
KIAA0737
Alias_symbol (synonym)LCP1
Other aliasMIG7
HGNC (Hugo) TOX4
LocusID (NCBI) 9878
Atlas_Id 52860
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 21477176 and ends at 21499177 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BCL6 (3q27.3) / TOX4 (14q11.2)CHD8 (14q11.2) / TOX4 (14q11.2)NOL4 (18q12.1) / TOX4 (14q11.2)
SF3A3 (1p34.3) / TOX4 (14q11.2)TOX4 (14q11.2) / BAP1 (3p21.1)TOX4 (14q11.2) / BCL6 (3q27.3)
TOX4 (14q11.2) / RPS27A (2p16.1)CHD8 14q11.2 / TOX4 14q11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TOX4   20161
Cards
Entrez_Gene (NCBI)TOX4  9878  TOX high mobility group box family member 4
AliasesC14orf92; KIAA0737; LCP1; MIG7
GeneCards (Weizmann)TOX4
Ensembl hg19 (Hinxton)ENSG00000092203 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000092203 [Gene_View]  chr14:21477176-21499177 [Contig_View]  TOX4 [Vega]
ICGC DataPortalENSG00000092203
TCGA cBioPortalTOX4
AceView (NCBI)TOX4
Genatlas (Paris)TOX4
WikiGenes9878
SOURCE (Princeton)TOX4
Genetics Home Reference (NIH)TOX4
Genomic and cartography
GoldenPath hg38 (UCSC)TOX4  -     chr14:21477176-21499177 +  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TOX4  -     14q11.2   [Description]    (hg19-Feb_2009)
EnsemblTOX4 - 14q11.2 [CytoView hg19]  TOX4 - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBITOX4 [Mapview hg19]  TOX4 [Mapview hg38]
OMIM614032   
Gene and transcription
Genbank (Entrez)AB018280 AK295913 AK298555 AK299807 AY305872
RefSeq transcript (Entrez)NM_001303523 NM_014828
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TOX4
Cluster EST : UnigeneHs.555910 [ NCBI ]
CGAP (NCI)Hs.555910
Alternative Splicing GalleryENSG00000092203
Gene ExpressionTOX4 [ NCBI-GEO ]   TOX4 [ EBI - ARRAY_EXPRESS ]   TOX4 [ SEEK ]   TOX4 [ MEM ]
Gene Expression Viewer (FireBrowse)TOX4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9878
GTEX Portal (Tissue expression)TOX4
Human Protein AtlasENSG00000092203-TOX4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94842   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94842  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94842
Splice isoforms : SwissVarO94842
PhosPhoSitePlusO94842
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)HMG_box_dom   
Domain families : Pfam (Sanger)HMG_box (PF00505)   
Domain families : Pfam (NCBI)pfam00505   
Domain families : Smart (EMBL)HMG (SM00398)  
Conserved Domain (NCBI)TOX4
DMDM Disease mutations9878
Blocks (Seattle)TOX4
SuperfamilyO94842
Human Protein Atlas [tissue]ENSG00000092203-TOX4 [tissue]
Peptide AtlasO94842
HPRD12661
IPIIPI00006586   IPI00910152   IPI00879111   IPI00878774   IPI00552769   IPI00879304   IPI00878684   IPI00878500   
Protein Interaction databases
DIP (DOE-UCLA)O94842
IntAct (EBI)O94842
FunCoupENSG00000092203
BioGRIDTOX4
STRING (EMBL)TOX4
ZODIACTOX4
Ontologies - Pathways
QuickGOO94842
Ontology : AmiGOnuclear chromosome, telomeric region  chromatin  DNA binding  protein binding  PTW/PP1 phosphatase complex  
Ontology : EGO-EBInuclear chromosome, telomeric region  chromatin  DNA binding  protein binding  PTW/PP1 phosphatase complex  
NDEx NetworkTOX4
Atlas of Cancer Signalling NetworkTOX4
Wikipedia pathwaysTOX4
Orthology - Evolution
OrthoDB9878
GeneTree (enSembl)ENSG00000092203
Phylogenetic Trees/Animal Genes : TreeFamTOX4
HOVERGENO94842
HOGENOMO94842
Homologs : HomoloGeneTOX4
Homology/Alignments : Family Browser (UCSC)TOX4
Gene fusions - Rearrangements
Fusion : MitelmanCHD8/TOX4 [14q11.2/14q11.2]  [t(14;14)(q11;q11)]  
Fusion: TCGA_MDACCCHD8 14q11.2 TOX4 14q11.2 BRCA
Tumor Fusion PortalTOX4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTOX4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TOX4
dbVarTOX4
ClinVarTOX4
1000_GenomesTOX4 
Exome Variant ServerTOX4
ExAC (Exome Aggregation Consortium)ENSG00000092203
GNOMAD BrowserENSG00000092203
Genetic variants : HAPMAP9878
Genomic Variants (DGV)TOX4 [DGVbeta]
DECIPHERTOX4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTOX4 
Mutations
ICGC Data PortalTOX4 
TCGA Data PortalTOX4 
Broad Tumor PortalTOX4
OASIS PortalTOX4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTOX4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTOX4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TOX4
DgiDB (Drug Gene Interaction Database)TOX4
DoCM (Curated mutations)TOX4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TOX4 (select a term)
intoGenTOX4
Cancer3DTOX4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614032   
Orphanet
DisGeNETTOX4
MedgenTOX4
Genetic Testing Registry TOX4
NextProtO94842 [Medical]
TSGene9878
GENETestsTOX4
Target ValidationTOX4
Huge Navigator TOX4 [HugePedia]
snp3D : Map Gene to Disease9878
BioCentury BCIQTOX4
ClinGenTOX4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9878
Chemical/Pharm GKB GenePA162406753
Clinical trialTOX4
Miscellaneous
canSAR (ICR)TOX4 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTOX4
EVEXTOX4
GoPubMedTOX4
iHOPTOX4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:39:18 CET 2017

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