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TOX4 (TOX high mobility group box family member 4)

Identity

Alias (NCBI)C14orf92
KIAA0737
LCP1
MIG7
HGNC (Hugo) TOX4
HGNC Alias symbLCP1
HGNC Previous nameC14orf92
 KIAA0737
HGNC Previous namechromosome 14 open reading frame 92
 KIAA0737
LocusID (NCBI) 9878
Atlas_Id 52860
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 21477195 and ends at 21499170 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BCL6 (3q27.3) / TOX4 (14q11.2)CHD8 (14q11.2) / TOX4 (14q11.2)NOL4 (18q12.1) / TOX4 (14q11.2)
SF3A3 (1p34.3) / TOX4 (14q11.2)TOX4 (14q11.2) / BAP1 (3p21.1)TOX4 (14q11.2) / BCL6 (3q27.3)
TOX4 (14q11.2) / RPS27A (2p16.1)CHD8 14q11.2 / TOX4 14q11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TOX4   20161
Cards
Entrez_Gene (NCBI)TOX4    TOX high mobility group box family member 4
AliasesC14orf92; KIAA0737; LCP1; MIG7
GeneCards (Weizmann)TOX4
Ensembl hg19 (Hinxton)ENSG00000092203 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000092203 [Gene_View]  ENSG00000092203 [Sequence]  chr14:21477195-21499170 [Contig_View]  TOX4 [Vega]
ICGC DataPortalENSG00000092203
TCGA cBioPortalTOX4
AceView (NCBI)TOX4
Genatlas (Paris)TOX4
SOURCE (Princeton)TOX4
Genetics Home Reference (NIH)TOX4
Genomic and cartography
GoldenPath hg38 (UCSC)TOX4  -     chr14:21477195-21499170 +  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TOX4  -     14q11.2   [Description]    (hg19-Feb_2009)
GoldenPathTOX4 - 14q11.2 [CytoView hg19]  TOX4 - 14q11.2 [CytoView hg38]
ImmunoBaseENSG00000092203
Genome Data Viewer NCBITOX4 [Mapview hg19]  
OMIM614032   
Gene and transcription
Genbank (Entrez)AB018280 AK295913 AK298555 AK299807 AY305872
RefSeq transcript (Entrez)NM_001303523 NM_014828
Consensus coding sequences : CCDS (NCBI)TOX4
Gene ExpressionTOX4 [ NCBI-GEO ]   TOX4 [ EBI - ARRAY_EXPRESS ]   TOX4 [ SEEK ]   TOX4 [ MEM ]
Gene Expression Viewer (FireBrowse)TOX4 [ Firebrowse - Broad ]
GenevisibleExpression of TOX4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9878
GTEX Portal (Tissue expression)TOX4
Human Protein AtlasENSG00000092203-TOX4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94842   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94842  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94842
PhosPhoSitePlusO94842
Domaine pattern : Prosite (Expaxy)HMG_BOX_2 (PS50118)   
Domains : Interpro (EBI)HMG_box_dom    HMG_box_dom_sf    TOX4   
Domain families : Pfam (Sanger)HMG_box (PF00505)   
Domain families : Pfam (NCBI)pfam00505   
Domain families : Smart (EMBL)HMG (SM00398)  
Conserved Domain (NCBI)TOX4
SuperfamilyO94842
AlphaFold pdb e-kbO94842   
Human Protein Atlas [tissue]ENSG00000092203-TOX4 [tissue]
HPRD12661
Protein Interaction databases
DIP (DOE-UCLA)O94842
IntAct (EBI)O94842
BioGRIDTOX4
STRING (EMBL)TOX4
ZODIACTOX4
Ontologies - Pathways
QuickGOO94842
Ontology : AmiGOchromosome, telomeric region  chromatin  protein binding  nucleus  regulation of transcription by RNA polymerase II  chromatin DNA binding  PTW/PP1 phosphatase complex  
Ontology : EGO-EBIchromosome, telomeric region  chromatin  protein binding  nucleus  regulation of transcription by RNA polymerase II  chromatin DNA binding  PTW/PP1 phosphatase complex  
NDEx NetworkTOX4
Atlas of Cancer Signalling NetworkTOX4
Wikipedia pathwaysTOX4
Orthology - Evolution
OrthoDB9878
GeneTree (enSembl)ENSG00000092203
Phylogenetic Trees/Animal Genes : TreeFamTOX4
Homologs : HomoloGeneTOX4
Homology/Alignments : Family Browser (UCSC)TOX4
Gene fusions - Rearrangements
Fusion : MitelmanCHD8/TOX4 [14q11.2/14q11.2]  
Fusion : QuiverTOX4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTOX4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TOX4
dbVarTOX4
ClinVarTOX4
MonarchTOX4
1000_GenomesTOX4 
Exome Variant ServerTOX4
GNOMAD BrowserENSG00000092203
Varsome BrowserTOX4
ACMGTOX4 variants
VarityO94842
Genomic Variants (DGV)TOX4 [DGVbeta]
DECIPHERTOX4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTOX4 
Mutations
ICGC Data PortalTOX4 
TCGA Data PortalTOX4 
Broad Tumor PortalTOX4
OASIS PortalTOX4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTOX4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTOX4
Mutations and Diseases : HGMDTOX4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTOX4
DgiDB (Drug Gene Interaction Database)TOX4
DoCM (Curated mutations)TOX4
CIViC (Clinical Interpretations of Variants in Cancer)TOX4
Cancer3DTOX4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614032   
Orphanet
DisGeNETTOX4
MedgenTOX4
Genetic Testing Registry TOX4
NextProtO94842 [Medical]
GENETestsTOX4
Target ValidationTOX4
Huge Navigator TOX4 [HugePedia]
ClinGenTOX4
Clinical trials, drugs, therapy
MyCancerGenomeTOX4
Protein Interactions : CTDTOX4
Pharm GKB GenePA162406753
PharosO94842
Clinical trialTOX4
Miscellaneous
canSAR (ICR)TOX4
HarmonizomeTOX4
DataMed IndexTOX4
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTOX4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:35:57 CEST 2021

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