TP53BP1 (tumor protein p53 binding protein 1)

Identity

Other names	53BP1
	FLJ41424
	MGC138366
	p202
HGNC	TP53BP1
Location	15q15-q21
Location_base_pair	Starts at 41486699 and ends at 41590028 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TP53BP1   11999
Entrez_Gene	TP53BP1  7158  tumor protein p53 binding protein 1
	Cards
GeneCards	TP53BP1
Ensembl	TP53BP1 [Search_View]   ENSG00000067369 [Gene_View]
Genatlas	TP53BP1
GeneLynx	TP53BP1
eGenome	TP53BP1
euGene	7158
	Genomic and cartography
GoldenPath	TP53BP1  -     chr15:41486699-41590028 -  15q15.3   [Description]    (hg18-March_2006)
Ensembl	TP53BP1 - 15q15.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	TP53BP1
	Gene and transcription
Genbank	AB210025 [ ENTREZ ]
Genbank	AF078776 [ ENTREZ ]
Genbank	AK123418 [ ENTREZ ]
Genbank	AK292915 [ ENTREZ ]
Genbank	AK307405 [ ENTREZ ]
RefSeq	NM_005657 [ SRS ]    NM_005657 [ ENTREZ ]
RefSeq	AC_000058 [ SRS ]    AC_000058 [ ENTREZ ]
RefSeq	AC_000147 [ SRS ]    AC_000147 [ ENTREZ ]
RefSeq	NC_000015 [ SRS ]    NC_000015 [ ENTREZ ]
RefSeq	NT_010194 [ SRS ]    NT_010194 [ ENTREZ ]
RefSeq	NW_001838214 [ SRS ]    NW_001838214 [ ENTREZ ]
RefSeq	NW_925840 [ SRS ]    NW_925840 [ ENTREZ ]
AceView	TP53BP1 AceView - NCBI
Unigene	Hs.440968 [ SRS ]    Hs.440968 [ NCBI ]     HS440968 [ spliceNest ]
Fast-db	3537 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q12888 [ SRS]    Q12888 [ EXPASY ]     Q12888 [ INTERPRO ]     Q12888 [ UNIPROT ]
Prosite	PS50172 BRCT [ SRS ]    PS50172 BRCT [ Expasy ]
Interpro	IPR015125 53-BP1_Tudor [ SRS ]    IPR015125 53-BP1_Tudor [ EBI ]
Interpro	IPR001357 BRCT [ SRS ]    IPR001357 BRCT [ EBI ]
Interpro	IPR014722 Transl_SH3_like_sub [ SRS ]    IPR014722 Transl_SH3_like_sub [ EBI ]
CluSTr	Q12888
Pfam	PF09038 53-BP1_Tudor [ SRS ]    PF09038 53-BP1_Tudor [ Sanger ]    pfam09038 [ NCBI-CDD ]
Pfam	PF00533 BRCT [ SRS ]    PF00533 BRCT [ Sanger ]    pfam00533 [ NCBI-CDD ]
Smart	SM00292 BRCT [EMBL]
Blocks	Q12888
PDB	1GZH [ SRS ]    1GZH [ PdbSum ],   1GZH [ IMB ]   1GZH [ RSDB ]
PDB	1KZY [ SRS ]    1KZY [ PdbSum ],   1KZY [ IMB ]   1KZY [ RSDB ]
PDB	1XNI [ SRS ]    1XNI [ PdbSum ],   1XNI [ IMB ]   1XNI [ RSDB ]
PDB	2G3R [ SRS ]    2G3R [ PdbSum ],   2G3R [ IMB ]   2G3R [ RSDB ]
PDB	2IG0 [ SRS ]    2IG0 [ PdbSum ],   2IG0 [ IMB ]   2IG0 [ RSDB ]
HPRD	05569
	Protein Interaction databases
DIP	Q12888
IntAct	Q12888
	Polymorphism : SNP, mutations, diseases
OMIM	605230    [ map ]
GENECLINICS	605230
SNP	TP53BP1 [dbSNP-NCBI]
SNP	NM_005657 [SNP-NCI]
SNP	TP53BP1 [GeneSNPs - Utah]  TP53BP1] [HGBASE - SRS]
HAPMAP	TP53BP1 [HAPMAP]
COSMIC	TP53BP1 [Somatic mutation (COSMIC-CGP-Sanger)]
TICdb	condensed [Translocation breakpoints In Cancer]
HGMD	TP53BP1
	General knowledge
Family Browser	TP53BP1 [UCSC Family Browser]
SOURCE	NM_005657
SMD	Hs.440968
SAGE	Hs.440968
GO	condensed chromosome kinetochore [Amigo]  condensed chromosome kinetochore
GO	damaged DNA binding [Amigo]  damaged DNA binding
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	nucleoplasm [Amigo]  nucleoplasm
GO	replication fork [Amigo]  replication fork
GO	cytoplasm [Amigo]  cytoplasm
GO	DNA repair [Amigo]  DNA repair
GO	transcription [Amigo]  transcription
GO	transcription activator activity [Amigo]  transcription activator activity
GO	positive regulation of transcription, DNA-dependent [Amigo]  positive regulation of transcription, DNA-dependent
PubGene	TP53BP1
TreeFam	TP53BP1
CTD	7158 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TP53BP1 Related clones (RZPD - Berlin)
	PubMed
PubMed	66 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:35:57 2008