TP53I11 (tumor protein p53 inducible protein 11)

2003-10-01  

Identity

HGNC
TP53I11
LOCATION
11p11.2
LOCUSID
9537
ALIAS
PIG11
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9537
MIM: 617867
HGNC: 16842
Ensembl: ENSG00000175274

Variants:

dbSNP: 9537
ClinVar: 9537
TCGA: ENSG00000175274
COSMIC: TP53I11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175274ENST00000308212O14683
ENSG00000175274ENST00000354556E9PPM1
ENSG00000175274ENST00000395648O14683
ENSG00000175274ENST00000525138E9PIN5
ENSG00000175274ENST00000525145E9PIK4
ENSG00000175274ENST00000525680O14683
ENSG00000175274ENST00000525683E9PQ46
ENSG00000175274ENST00000527685E9PKN9
ENSG00000175274ENST00000528290E9PMY0
ENSG00000175274ENST00000528473E9PKZ4
ENSG00000175274ENST00000530035E9PS55
ENSG00000175274ENST00000531928U3KQ32
ENSG00000175274ENST00000532253E9PNB3
ENSG00000175274ENST00000533443E9PMW4
ENSG00000175274ENST00000533937E9PN66
ENSG00000175274ENST00000533940O14683
ENSG00000175274ENST00000616990O14683
ENSG00000175274ENST00000627720E9PNB3

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
161703292005Jasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cells.14
190969152009PIG11 is involved in hepatocellular carcinogenesis and its over-expression promotes Hepg2 cell apoptosis.10
128836912003P53-induced gene 11 (PIG11) involved in arsenic trioxide-induced apoptosis in human gastric cancer MGC-803 cells.5
152256152004A P53 target gene, PIG11, contributes to chemosensitivity of cells to arsenic trioxide.5
174825692007PIG11 protein binds to DNA in sequence-independent manner in vitro.2
303766102019Loss of TP53I11 Enhances the Extracellular Matrix-independent Survival by Promoting Activation of AMPK.1
309403202019TP53I11 suppresses epithelial-mesenchymal transition and metastasis of breast cancer cells.0

Citation

Dessen P

TP53I11 (tumor protein p53 inducible protein 11)

Atlas Genet Cytogenet Oncol Haematol. 2003-10-01

Online version: http://atlasgeneticsoncology.org/gene/42669/tp53i11