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TP53I3 (tumor protein p53 inducible protein 3)

Identity

Alias_symbol (synonym)PIG3
Other alias
HGNC (Hugo) TP53I3
LocusID (NCBI) 9540
Atlas_Id 42670
Location 2p23.3  [Link to chromosome band 2p23]
Location_base_pair Starts at 24077433 and ends at 24084331 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PAXBP1 (21q22.11) / TP53I3 (2p23.3)GCFC1 TP53I3 2p23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TP53I3   19373
Cards
Entrez_Gene (NCBI)TP53I3  9540  tumor protein p53 inducible protein 3
AliasesPIG3
GeneCards (Weizmann)TP53I3
Ensembl hg19 (Hinxton)ENSG00000115129 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115129 [Gene_View]  chr2:24077433-24084331 [Contig_View]  TP53I3 [Vega]
ICGC DataPortalENSG00000115129
TCGA cBioPortalTP53I3
AceView (NCBI)TP53I3
Genatlas (Paris)TP53I3
WikiGenes9540
SOURCE (Princeton)TP53I3
Genetics Home Reference (NIH)TP53I3
Genomic and cartography
GoldenPath hg38 (UCSC)TP53I3  -     chr2:24077433-24084331 -  2p23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TP53I3  -     2p23.3   [Description]    (hg19-Feb_2009)
EnsemblTP53I3 - 2p23.3 [CytoView hg19]  TP53I3 - 2p23.3 [CytoView hg38]
Mapping of homologs : NCBITP53I3 [Mapview hg19]  TP53I3 [Mapview hg38]
OMIM605171   
Gene and transcription
Genbank (Entrez)AF010309 AK223382 AK297579 AY371700 BC000474
RefSeq transcript (Entrez)NM_001206802 NM_004881 NM_147184
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TP53I3
Cluster EST : UnigeneHs.733381 [ NCBI ]
CGAP (NCI)Hs.733381
Alternative Splicing GalleryENSG00000115129
Gene ExpressionTP53I3 [ NCBI-GEO ]   TP53I3 [ EBI - ARRAY_EXPRESS ]   TP53I3 [ SEEK ]   TP53I3 [ MEM ]
Gene Expression Viewer (FireBrowse)TP53I3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9540
GTEX Portal (Tissue expression)TP53I3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ53FA7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ53FA7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ53FA7
Splice isoforms : SwissVarQ53FA7
Catalytic activity : Enzyme1.-.-.- [ Enzyme-Expasy ]   1.-.-.-1.-.-.- [ IntEnz-EBI ]   1.-.-.- [ BRENDA ]   1.-.-.- [ KEGG ]   
PhosPhoSitePlusQ53FA7
Domains : Interpro (EBI)ADH_C    ADH_N    GroES-like    NAD(P)-bd_dom    PKS_ER    Quinone_OxRdtase_PIG3   
Domain families : Pfam (Sanger)ADH_N (PF08240)    ADH_zinc_N (PF00107)   
Domain families : Pfam (NCBI)pfam08240    pfam00107   
Domain families : Smart (EMBL)PKS_ER (SM00829)  
Conserved Domain (NCBI)TP53I3
DMDM Disease mutations9540
Blocks (Seattle)TP53I3
PDB (SRS)2J8Z    2OBY   
PDB (PDBSum)2J8Z    2OBY   
PDB (IMB)2J8Z    2OBY   
PDB (RSDB)2J8Z    2OBY   
Structural Biology KnowledgeBase2J8Z    2OBY   
SCOP (Structural Classification of Proteins)2J8Z    2OBY   
CATH (Classification of proteins structures)2J8Z    2OBY   
SuperfamilyQ53FA7
Human Protein AtlasENSG00000115129
Peptide AtlasQ53FA7
HPRD05527
IPIIPI00384643   IPI00418440   IPI00894488   
Protein Interaction databases
DIP (DOE-UCLA)Q53FA7
IntAct (EBI)Q53FA7
FunCoupENSG00000115129
BioGRIDTP53I3
STRING (EMBL)TP53I3
ZODIACTP53I3
Ontologies - Pathways
QuickGOQ53FA7
Ontology : AmiGONADPH:quinone reductase activity  NADPH:quinone reductase activity  cytosol  NADP metabolic process  protein homodimerization activity  regulation of apoptotic process  quinone binding  oxidation-reduction process  extracellular exosome  NADPH binding  
Ontology : EGO-EBINADPH:quinone reductase activity  NADPH:quinone reductase activity  cytosol  NADP metabolic process  protein homodimerization activity  regulation of apoptotic process  quinone binding  oxidation-reduction process  extracellular exosome  NADPH binding  
Pathways : KEGGp53 signaling pathway   
NDEx NetworkTP53I3
Atlas of Cancer Signalling NetworkTP53I3
Wikipedia pathwaysTP53I3
Orthology - Evolution
OrthoDB9540
GeneTree (enSembl)ENSG00000115129
Phylogenetic Trees/Animal Genes : TreeFamTP53I3
HOVERGENQ53FA7
HOGENOMQ53FA7
Homologs : HomoloGeneTP53I3
Homology/Alignments : Family Browser (UCSC)TP53I3
Gene fusions - Rearrangements
Fusion : MitelmanPAXBP1/TP53I3 [21q22.11/2p23.3]  [t(2;21)(p23;q22)]  
Fusion: TCGAGCFC1 TP53I3 2p23.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTP53I3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TP53I3
dbVarTP53I3
ClinVarTP53I3
1000_GenomesTP53I3 
Exome Variant ServerTP53I3
ExAC (Exome Aggregation Consortium)TP53I3 (select the gene name)
Genetic variants : HAPMAP9540
Genomic Variants (DGV)TP53I3 [DGVbeta]
DECIPHERTP53I3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTP53I3 
Mutations
ICGC Data PortalTP53I3 
TCGA Data PortalTP53I3 
Broad Tumor PortalTP53I3
OASIS PortalTP53I3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTP53I3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTP53I3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TP53I3
DgiDB (Drug Gene Interaction Database)TP53I3
DoCM (Curated mutations)TP53I3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TP53I3 (select a term)
intoGenTP53I3
Cancer3DTP53I3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605171   
Orphanet
MedgenTP53I3
Genetic Testing Registry TP53I3
NextProtQ53FA7 [Medical]
TSGene9540
GENETestsTP53I3
Target ValidationTP53I3
Huge Navigator TP53I3 [HugePedia]
snp3D : Map Gene to Disease9540
BioCentury BCIQTP53I3
ClinGenTP53I3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9540
Chemical/Pharm GKB GenePA134923704
Clinical trialTP53I3
Miscellaneous
canSAR (ICR)TP53I3 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTP53I3
EVEXTP53I3
GoPubMedTP53I3
iHOPTP53I3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:10:15 CEST 2017

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