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TPGS2 (tubulin polyglutamylase complex subunit 2)

Identity

Alias_namesC18orf10
chromosome 18 open reading frame 10
Alias_symbol (synonym)DKFZP586M1523
HsT3006
Other aliasHMFN0601
L17
PGs2
HGNC (Hugo) TPGS2
LocusID (NCBI) 25941
Atlas_Id 54718
Location 18q12.2  [Link to chromosome band 18q12]
Location_base_pair Starts at 34374069 and ends at 34409179 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARHGAP5 (14q12) / TPGS2 (18q12.2)PDCD1LG2 (9p24.1) / TPGS2 (18q12.2)TPGS2 (18q12.2) / MCM4 (8q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TPGS2   24561
Cards
Entrez_Gene (NCBI)TPGS2  25941  tubulin polyglutamylase complex subunit 2
AliasesC18orf10; HMFN0601; L17; PGs2
GeneCards (Weizmann)TPGS2
Ensembl hg19 (Hinxton)ENSG00000134779 [Gene_View]  chr18:34374069-34409179 [Contig_View]  TPGS2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000134779 [Gene_View]  chr18:34374069-34409179 [Contig_View]  TPGS2 [Vega]
ICGC DataPortalENSG00000134779
TCGA cBioPortalTPGS2
AceView (NCBI)TPGS2
Genatlas (Paris)TPGS2
WikiGenes25941
SOURCE (Princeton)TPGS2
Genetics Home Reference (NIH)TPGS2
Genomic and cartography
GoldenPath hg19 (UCSC)TPGS2  -     chr18:34374069-34409179 -  18q12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TPGS2  -     18q12.2   [Description]    (hg38-Dec_2013)
EnsemblTPGS2 - 18q12.2 [CytoView hg19]  TPGS2 - 18q12.2 [CytoView hg38]
Mapping of homologs : NCBITPGS2 [Mapview hg19]  TPGS2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA677381 AB073382 AK000543 AK295817 AL050225
RefSeq transcript (Entrez)NM_001271949 NM_001271950 NM_001271951 NM_001271952 NM_001271953 NM_001271954 NM_001271955 NM_001271956 NM_015476
RefSeq genomic (Entrez)NC_000018 NC_018929 NT_010966 NW_004929410
Consensus coding sequences : CCDS (NCBI)TPGS2
Cluster EST : UnigeneHs.436636 [ NCBI ]
CGAP (NCI)Hs.436636
Alternative Splicing GalleryENSG00000134779
Gene ExpressionTPGS2 [ NCBI-GEO ]   TPGS2 [ EBI - ARRAY_EXPRESS ]   TPGS2 [ SEEK ]   TPGS2 [ MEM ]
Gene Expression Viewer (FireBrowse)TPGS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25941
GTEX Portal (Tissue expression)TPGS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ68CL5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ68CL5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ68CL5
Splice isoforms : SwissVarQ68CL5
PhosPhoSitePlusQ68CL5
Domains : Interpro (EBI)SMI1/KNR4-like_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)SMI1_KNR4 (SM00860)  
Conserved Domain (NCBI)TPGS2
DMDM Disease mutations25941
Blocks (Seattle)TPGS2
SuperfamilyQ68CL5
Human Protein AtlasENSG00000134779
Peptide AtlasQ68CL5
HPRD12684
IPIIPI00414449   IPI00607682   IPI00470794   
Protein Interaction databases
DIP (DOE-UCLA)Q68CL5
IntAct (EBI)Q68CL5
FunCoupENSG00000134779
BioGRIDTPGS2
STRING (EMBL)TPGS2
ZODIACTPGS2
Ontologies - Pathways
QuickGOQ68CL5
Ontology : AmiGOcytoplasm  microtubule  
Ontology : EGO-EBIcytoplasm  microtubule  
NDEx NetworkTPGS2
Atlas of Cancer Signalling NetworkTPGS2
Wikipedia pathwaysTPGS2
Orthology - Evolution
OrthoDB25941
GeneTree (enSembl)ENSG00000134779
Phylogenetic Trees/Animal Genes : TreeFamTPGS2
HOVERGENQ68CL5
HOGENOMQ68CL5
Homologs : HomoloGeneTPGS2
Homology/Alignments : Family Browser (UCSC)TPGS2
Gene fusions - Rearrangements
Fusion : MitelmanARHGAP5/TPGS2 [14q12/18q12.2]  [t(14;18)(q12;q12)]  
Fusion : MitelmanPDCD1LG2/TPGS2 [9p24.1/18q12.2]  [t(9;18)(p24;q12)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTPGS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPGS2
dbVarTPGS2
ClinVarTPGS2
1000_GenomesTPGS2 
Exome Variant ServerTPGS2
ExAC (Exome Aggregation Consortium)TPGS2 (select the gene name)
Genetic variants : HAPMAP25941
Genomic Variants (DGV)TPGS2 [DGVbeta]
DECIPHER (Syndromes)18:34374069-34409179  ENSG00000134779
CONAN: Copy Number AnalysisTPGS2 
Mutations
ICGC Data PortalTPGS2 
TCGA Data PortalTPGS2 
Broad Tumor PortalTPGS2
OASIS PortalTPGS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTPGS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTPGS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TPGS2
DgiDB (Drug Gene Interaction Database)TPGS2
DoCM (Curated mutations)TPGS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TPGS2 (select a term)
intoGenTPGS2
Cancer3DTPGS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTPGS2
Genetic Testing Registry TPGS2
NextProtQ68CL5 [Medical]
TSGene25941
GENETestsTPGS2
Huge Navigator TPGS2 [HugePedia]
snp3D : Map Gene to Disease25941
BioCentury BCIQTPGS2
ClinGenTPGS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25941
Chemical/Pharm GKB GenePA128394637
Clinical trialTPGS2
Miscellaneous
canSAR (ICR)TPGS2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTPGS2
EVEXTPGS2
GoPubMedTPGS2
iHOPTPGS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:23:11 CEST 2017

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