TPP1 (tripeptidyl peptidase I)

Identity

Other names	CLN2
	GIG1
	LPIC
	MGC21297
	TPP I
HGNC	TPP1
Location	11p15
Location_base_pair	Starts at 6590573 and ends at 6597268 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	TPP1   2073
Entrez_Gene	TPP1  1200  tripeptidyl peptidase I
	Cards
GeneCards	TPP1
Ensembl	ENSG00000166340 [Gene_View]  TPP1 [Vega]
Genatlas	TPP1
	Genomic and cartography
GoldenPath	TPP1  -  11p15   chr11:6590573-6597268 -  11p15.4   [Description]    (hg18-March_2006)
Ensembl	TPP1 - 11p15.4 [CytoView]
NCBI	Mapview
OMIM	204500 Disease map [OMIM]
OMIM	607998 Disease map [OMIM]
HomoloGene	TPP1
	Gene and transcription
Genbank	AF017456 [ ENTREZ ]
Genbank	AI023962 [ ENTREZ ]
Genbank	AK222499 [ ENTREZ ]
Genbank	AK222538 [ ENTREZ ]
Genbank	AK312388 [ ENTREZ ]
RefSeq	NM_000391 [ SRS ]    NM_000391 [ ENTREZ ]
RefSeq	AC_000054 [ SRS ]    AC_000054 [ ENTREZ ]
RefSeq	AC_000143 [ SRS ]    AC_000143 [ ENTREZ ]
RefSeq	NC_000011 [ SRS ]    NC_000011 [ ENTREZ ]
RefSeq	NT_009237 [ SRS ]    NT_009237 [ ENTREZ ]
RefSeq	NW_001838021 [ SRS ]    NW_001838021 [ ENTREZ ]
RefSeq	NW_925006 [ SRS ]    NW_925006 [ ENTREZ ]
CCDS	TPP1 CCDS - NCBI
AceView	TPP1 AceView - NCBI
Unigene	Hs.523454 [ SRS ]    Hs.523454 [ NCBI ]
Fast-db	2127 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O14773 [ SRS]    O14773 [ EXPASY ]     O14773 [ INTERPRO ]     O14773 [ UNIPROT ] O14773 [ VarSplice FASTA ]
Interpro	IPR000209 Pept_S8_S53 [ SRS ]    IPR000209 Pept_S8_S53 [ EBI ]
Interpro	IPR015366 Peptidase_S53_propep [ SRS ]    IPR015366 Peptidase_S53_propep [ EBI ]
CluSTr	O14773
Pfam	PF09286 Pro-kuma_activ [ SRS ]    PF09286 Pro-kuma_activ [ Sanger ]    pfam09286 [ NCBI-CDD ]
Blocks	O14773
PDB	1R60 [ SRS ]    1R60 [ PdbSum ],   1R60 [ IMB ]   1R60 [ RSDB ]
HPRD	06415
	Protein Interaction databases
DIP	O14773
IntAct	O14773
	Polymorphism : SNP, mutations, diseases
OMIM	204500    [ map ]
OMIM	607998    [ map ]
GENETests	204500
GENETests	607998
SNP	TPP1 [dbSNP-NCBI]
SNP	NM_000391 [SNP-NCI]
SNP	TPP1 [GeneSNPs - Utah]  TPP1] [HGBASE - SRS]
HAPMAP	TPP1 [HAPMAP]
HGMD	TPP1
Genetic Association	TPP1
CDC HuGE	TPP1
	General knowledge
Family Browser	TPP1 [UCSC Family Browser]
SOURCE	NM_000391
SMD	Hs.523454
SAGE	Hs.523454
Enzyme	3.4.14.9 [ Enzyme-Expasy ]   3.4.14.9 [ Enzyme-SRS ]   3.4.14.9 [ IntEnz-EBI ]   3.4.14.9 [ BRENDA ]   3.4.14.9 [ KEGG ]
GO	subtilase activity [Amigo]  subtilase activity
GO	protein binding [Amigo]  protein binding
GO	soluble fraction [Amigo]  soluble fraction
GO	lysosome [Amigo]  lysosome
GO	lysosome [Amigo]  lysosome
GO	proteolysis [Amigo]  proteolysis
GO	lipid metabolic process [Amigo]  lipid metabolic process
GO	nervous system development [Amigo]  nervous system development
GO	tripeptidyl-peptidase I activity [Amigo]  tripeptidyl-peptidase I activity
GO	tripeptidyl-peptidase I activity [Amigo]  tripeptidyl-peptidase I activity
GO	tripeptidyl-peptidase I activity [Amigo]  tripeptidyl-peptidase I activity
GO	protein catabolic process [Amigo]  protein catabolic process
GO	melanosome [Amigo]  melanosome
GO	peptide catabolic process [Amigo]  peptide catabolic process
GO	bone resorption [Amigo]  bone resorption
PubGene	TPP1
TreeFam	TPP1
CTD	1200 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	TPP1 Related clones (RZPD - Berlin)
	PubMed
PubMed	46 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:16:52 2008