Identity
HGNC
LOCATION
13q33.1
LOCUSID
ALIAS
IMD78,TPP-2,TPP-II,TPPII
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7174
MIM: 190470
HGNC: 12016
Ensembl: ENSG00000134900
Variants:
dbSNP: 7174
ClinVar: 7174
TCGA: ENSG00000134900
COSMIC: TPP2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35466366 | 2022 | Unveiling a novel serpinB2-tripeptidyl peptidase II signaling axis during senescence. | 0 |
| 35466366 | 2022 | Unveiling a novel serpinB2-tripeptidyl peptidase II signaling axis during senescence. | 0 |
| 33586135 | 2021 | Immune deficiency, autoimmune disease and intellectual disability: A pleiotropic disorder caused by biallelic variants in the TPP2 gene. | 3 |
| 33586135 | 2021 | Immune deficiency, autoimmune disease and intellectual disability: A pleiotropic disorder caused by biallelic variants in the TPP2 gene. | 3 |
| 25414442 | 2015 | Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency. | 33 |
| 26041847 | 2015 | Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2. | 6 |
| 26169984 | 2015 | Novel protein-protein interactions of TPPII, p53, and SIRT7. | 10 |
| 25414442 | 2015 | Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency. | 33 |
| 26041847 | 2015 | Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2. | 6 |
| 26169984 | 2015 | Novel protein-protein interactions of TPPII, p53, and SIRT7. | 10 |
| 25303791 | 2014 | TPPII, MYBBP1A and CDK2 form a protein-protein interaction network. | 1 |
| 25525876 | 2014 | Dual proteolytic pathways govern glycolysis and immune competence. | 25 |
| 25303791 | 2014 | TPPII, MYBBP1A and CDK2 form a protein-protein interaction network. | 1 |
| 25525876 | 2014 | Dual proteolytic pathways govern glycolysis and immune competence. | 25 |
| 22986808 | 2013 | Tripeptidyl peptidase II in human oral squamous cell carcinoma. | 12 |
Citation
Dessen P
TPP2 (tripeptidyl peptidase 2)
Atlas Genet Cytogenet Oncol Haematol. 2009-04-01
Online version: http://atlasgeneticsoncology.org/gene/50836/tpp2
