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TPRA1 (transmembrane protein adipocyte associated 1)

Identity

Alias (NCBI)GPR175
TMEM227
TPRA40
HGNC (Hugo) TPRA1
HGNC Alias symbTPRA40
FLJ32197
TMEM227
HGNC Alias nametransmembrane protein 227
HGNC Previous nameGPR175
HGNC Previous nameG protein-coupled receptor 175
 transmembrane protein, adipocyte asscociated 1
LocusID (NCBI) 131601
Atlas_Id 75079
Location 3q21.3  [Link to chromosome band 3q21]
Location_base_pair Starts at 127571232 and ends at 127598231 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCDC90B (11q14.1) / TPRA1 (3q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TPRA1   30413
Cards
Entrez_Gene (NCBI)TPRA1    transmembrane protein adipocyte associated 1
AliasesGPR175; TMEM227; TPRA40
GeneCards (Weizmann)TPRA1
Ensembl hg19 (Hinxton)ENSG00000163870 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163870 [Gene_View]  ENSG00000163870 [Sequence]  chr3:127571232-127598231 [Contig_View]  TPRA1 [Vega]
ICGC DataPortalENSG00000163870
TCGA cBioPortalTPRA1
AceView (NCBI)TPRA1
Genatlas (Paris)TPRA1
SOURCE (Princeton)TPRA1
Genetics Home Reference (NIH)TPRA1
Genomic and cartography
GoldenPath hg38 (UCSC)TPRA1  -     chr3:127571232-127598231 -  3q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TPRA1  -     3q21.3   [Description]    (hg19-Feb_2009)
GoldenPathTPRA1 - 3q21.3 [CytoView hg19]  TPRA1 - 3q21.3 [CytoView hg38]
ImmunoBaseENSG00000163870
Genome Data Viewer NCBITPRA1 [Mapview hg19]  
OMIM608336   
Gene and transcription
Genbank (Entrez)AB037108 AF289568 AI248453 AK056759 BC017058
RefSeq transcript (Entrez)NM_001136053 NM_001142646 NM_001353001 NM_001353002 NM_001353003 NM_001353004 NM_001353005 NM_001353006 NM_001353007 NM_016372
Consensus coding sequences : CCDS (NCBI)TPRA1
Gene ExpressionTPRA1 [ NCBI-GEO ]   TPRA1 [ EBI - ARRAY_EXPRESS ]   TPRA1 [ SEEK ]   TPRA1 [ MEM ]
Gene Expression Viewer (FireBrowse)TPRA1 [ Firebrowse - Broad ]
GenevisibleExpression of TPRA1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)131601
GTEX Portal (Tissue expression)TPRA1
Human Protein AtlasENSG00000163870-TPRA1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86W33   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86W33  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86W33
PhosPhoSitePlusQ86W33
Domains : Interpro (EBI)TPRA1/CAND2/CAND8   
Domain families : Pfam (Sanger)Tmemb_40 (PF10160)   
Domain families : Pfam (NCBI)pfam10160   
Conserved Domain (NCBI)TPRA1
SuperfamilyQ86W33
AlphaFold pdb e-kbQ86W33   
Human Protein Atlas [tissue]ENSG00000163870-TPRA1 [tissue]
HPRD16318
Protein Interaction databases
DIP (DOE-UCLA)Q86W33
IntAct (EBI)Q86W33
BioGRIDTPRA1
STRING (EMBL)TPRA1
ZODIACTPRA1
Ontologies - Pathways
QuickGOQ86W33
Ontology : AmiGOG protein-coupled receptor activity  protein binding  lipid metabolic process  G protein-coupled receptor signaling pathway  aging  integral component of membrane  embryonic cleavage  negative regulation of mitotic cell cycle phase transition  
Ontology : EGO-EBIG protein-coupled receptor activity  protein binding  lipid metabolic process  G protein-coupled receptor signaling pathway  aging  integral component of membrane  embryonic cleavage  negative regulation of mitotic cell cycle phase transition  
NDEx NetworkTPRA1
Atlas of Cancer Signalling NetworkTPRA1
Wikipedia pathwaysTPRA1
Orthology - Evolution
OrthoDB131601
GeneTree (enSembl)ENSG00000163870
Phylogenetic Trees/Animal Genes : TreeFamTPRA1
Homologs : HomoloGeneTPRA1
Homology/Alignments : Family Browser (UCSC)TPRA1
Gene fusions - Rearrangements
Fusion : QuiverTPRA1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTPRA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPRA1
dbVarTPRA1
ClinVarTPRA1
MonarchTPRA1
1000_GenomesTPRA1 
Exome Variant ServerTPRA1
GNOMAD BrowserENSG00000163870
Varsome BrowserTPRA1
ACMGTPRA1 variants
VarityQ86W33
Genomic Variants (DGV)TPRA1 [DGVbeta]
DECIPHERTPRA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTPRA1 
Mutations
ICGC Data PortalTPRA1 
TCGA Data PortalTPRA1 
Broad Tumor PortalTPRA1
OASIS PortalTPRA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTPRA1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTPRA1
Mutations and Diseases : HGMDTPRA1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTPRA1
DgiDB (Drug Gene Interaction Database)TPRA1
DoCM (Curated mutations)TPRA1
CIViC (Clinical Interpretations of Variants in Cancer)TPRA1
Cancer3DTPRA1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608336   
Orphanet
DisGeNETTPRA1
MedgenTPRA1
Genetic Testing Registry TPRA1
NextProtQ86W33 [Medical]
GENETestsTPRA1
Target ValidationTPRA1
Huge Navigator TPRA1 [HugePedia]
ClinGenTPRA1
Clinical trials, drugs, therapy
MyCancerGenomeTPRA1
Protein Interactions : CTDTPRA1
Pharm GKB GenePA165698543
PharosQ86W33
Clinical trialTPRA1
Miscellaneous
canSAR (ICR)TPRA1
HarmonizomeTPRA1
DataMed IndexTPRA1
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTPRA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:26:37 CEST 2021

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