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TPRG1 (tumor protein p63 regulated 1)

Identity

Alias_namesFAM79B
family with sequence similarity 79
Alias_symbol (synonym)FLJ41238
FLJ43694
Other alias
HGNC (Hugo) TPRG1
LocusID (NCBI) 285386
Atlas_Id 49993
Location 3q28  [Link to chromosome band 3q28]
Location_base_pair Starts at 188889763 and ends at 189041271 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADCY2 (5p15.31) / TPRG1 (3q28)C3orf70 (3q27.2) / TPRG1 (3q28)FGFR3 (4p16.3) / TPRG1 (3q28)
IL1RAP (3q28) / TPRG1 (3q28)LMBR1 (7q36.3) / TPRG1 (3q28)SOX2 (3q26.33) / TPRG1 (3q28)
TPRG1 (3q28) / DGKG (3q27.2)TPRG1 (3q28) / SOX2 (3q26.33)XXYLT1 (3q29) / TPRG1 (3q28)
C3orf21 TPRG1 3q28C3orf70 3q27.2 / TPRG1 3q28FGFR3 4p16.3 / TPRG1 3q28
IL1RAP 3q28 / TPRG1 3q28LMBR1 7q36.3 / TPRG1 3q28TPRG1 3q28 / DGKG 3q27.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Lung: Translocations in Small Cell Carcinoma
Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)TPRG1   24759
Cards
Entrez_Gene (NCBI)TPRG1  285386  tumor protein p63 regulated 1
AliasesFAM79B
GeneCards (Weizmann)TPRG1
Ensembl hg19 (Hinxton)ENSG00000188001 [Gene_View]  chr3:188889763-189041271 [Contig_View]  TPRG1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000188001 [Gene_View]  chr3:188889763-189041271 [Contig_View]  TPRG1 [Vega]
ICGC DataPortalENSG00000188001
TCGA cBioPortalTPRG1
AceView (NCBI)TPRG1
Genatlas (Paris)TPRG1
WikiGenes285386
SOURCE (Princeton)TPRG1
Genetics Home Reference (NIH)TPRG1
Genomic and cartography
GoldenPath hg19 (UCSC)TPRG1  -     chr3:188889763-189041271 +  3q28   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TPRG1  -     3q28   [Description]    (hg38-Dec_2013)
EnsemblTPRG1 - 3q28 [CytoView hg19]  TPRG1 - 3q28 [CytoView hg38]
Mapping of homologs : NCBITPRG1 [Mapview hg19]  TPRG1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK123232 AK125682 BC101550 BC101552 CR737485
RefSeq transcript (Entrez)NM_198485
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)TPRG1
Cluster EST : UnigeneHs.729544 [ NCBI ]
CGAP (NCI)Hs.729544
Alternative Splicing GalleryENSG00000188001
Gene ExpressionTPRG1 [ NCBI-GEO ]   TPRG1 [ EBI - ARRAY_EXPRESS ]   TPRG1 [ SEEK ]   TPRG1 [ MEM ]
Gene Expression Viewer (FireBrowse)TPRG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)285386
GTEX Portal (Tissue expression)TPRG1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZUI0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZUI0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZUI0
Splice isoforms : SwissVarQ6ZUI0
PhosPhoSitePlusQ6ZUI0
Domains : Interpro (EBI)Inositol_phosphatase   
Domain families : Pfam (Sanger)hSac2 (PF12456)   
Domain families : Pfam (NCBI)pfam12456   
Conserved Domain (NCBI)TPRG1
DMDM Disease mutations285386
Blocks (Seattle)TPRG1
SuperfamilyQ6ZUI0
Human Protein AtlasENSG00000188001
Peptide AtlasQ6ZUI0
HPRD13451
IPIIPI00182342   IPI00926817   IPI00926561   IPI00926349   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZUI0
IntAct (EBI)Q6ZUI0
FunCoupENSG00000188001
BioGRIDTPRG1
STRING (EMBL)TPRG1
ZODIACTPRG1
Ontologies - Pathways
QuickGOQ6ZUI0
Ontology : AmiGOcytoplasm  
Ontology : EGO-EBIcytoplasm  
NDEx NetworkTPRG1
Atlas of Cancer Signalling NetworkTPRG1
Wikipedia pathwaysTPRG1
Orthology - Evolution
OrthoDB285386
GeneTree (enSembl)ENSG00000188001
Phylogenetic Trees/Animal Genes : TreeFamTPRG1
HOVERGENQ6ZUI0
HOGENOMQ6ZUI0
Homologs : HomoloGeneTPRG1
Homology/Alignments : Family Browser (UCSC)TPRG1
Gene fusions - Rearrangements
Fusion : MitelmanC3orf70/TPRG1 [3q27.2/3q28]  [t(3;3)(q27;q28)]  
Fusion : MitelmanFGFR3/TPRG1 [4p16.3/3q28]  [t(3;4)(q28;p16)]  
Fusion : MitelmanLMBR1/TPRG1 [7q36.3/3q28]  [t(3;7)(q28;q36)]  
Fusion : MitelmanSOX2/TPRG1 [3q26.33/3q28]  [t(3;3)(q26;q28)]  
Fusion : MitelmanTPRG1/DGKG [3q28/3q27.2]  [t(3;3)(q27;q28)]  
Fusion : MitelmanTPRG1/SOX2 [3q28/3q26.33]  [t(3;3)(q26;q28)]  
Fusion: TCGAC3orf21 TPRG1 3q28 LUSC
Fusion: TCGAC3orf70 3q27.2 TPRG1 3q28 BRCA
Fusion: TCGAFGFR3 4p16.3 TPRG1 3q28 HNSC
Fusion: TCGAIL1RAP 3q28 TPRG1 3q28 LUSC
Fusion: TCGALMBR1 7q36.3 TPRG1 3q28 BRCA
Fusion: TCGATPRG1 3q28 DGKG 3q27.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTPRG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPRG1
dbVarTPRG1
ClinVarTPRG1
1000_GenomesTPRG1 
Exome Variant ServerTPRG1
ExAC (Exome Aggregation Consortium)TPRG1 (select the gene name)
Genetic variants : HAPMAP285386
Genomic Variants (DGV)TPRG1 [DGVbeta]
DECIPHER (Syndromes)3:188889763-189041271  ENSG00000188001
CONAN: Copy Number AnalysisTPRG1 
Mutations
ICGC Data PortalTPRG1 
TCGA Data PortalTPRG1 
Broad Tumor PortalTPRG1
OASIS PortalTPRG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTPRG1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTPRG1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TPRG1
DgiDB (Drug Gene Interaction Database)TPRG1
DoCM (Curated mutations)TPRG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TPRG1 (select a term)
intoGenTPRG1
Cancer3DTPRG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTPRG1
Genetic Testing Registry TPRG1
NextProtQ6ZUI0 [Medical]
TSGene285386
GENETestsTPRG1
Huge Navigator TPRG1 [HugePedia]
snp3D : Map Gene to Disease285386
BioCentury BCIQTPRG1
ClinGenTPRG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD285386
Chemical/Pharm GKB GenePA162406838
Clinical trialTPRG1
Miscellaneous
canSAR (ICR)TPRG1 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTPRG1
EVEXTPRG1
GoPubMedTPRG1
iHOPTPRG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:23:13 CEST 2017

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