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TPRKB (TP53RK binding protein)

Identity

Alias (NCBI)CGI-121
CGI121
GAMOS5
HGNC (Hugo) TPRKB
HGNC Alias symbCGI-121
CGI121
LocusID (NCBI) 51002
Atlas_Id 75082
Location 2p13.1  [Link to chromosome band 2p13]
Location_base_pair Starts at 73729875 and ends at 73737345 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LOC284889 () / TPRKB (2p13.1)UBAP1 (9p13.3) / TPRKB (2p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TPRKB   24259
Cards
Entrez_Gene (NCBI)TPRKB    TP53RK binding protein
AliasesCGI-121; CGI121; GAMOS5
GeneCards (Weizmann)TPRKB
Ensembl hg19 (Hinxton)ENSG00000144034 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144034 [Gene_View]  ENSG00000144034 [Sequence]  chr2:73729875-73737345 [Contig_View]  TPRKB [Vega]
ICGC DataPortalENSG00000144034
TCGA cBioPortalTPRKB
AceView (NCBI)TPRKB
Genatlas (Paris)TPRKB
SOURCE (Princeton)TPRKB
Genetics Home Reference (NIH)TPRKB
Genomic and cartography
GoldenPath hg38 (UCSC)TPRKB  -     chr2:73729875-73737345 -  2p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TPRKB  -     2p13.1   [Description]    (hg19-Feb_2009)
GoldenPathTPRKB - 2p13.1 [CytoView hg19]  TPRKB - 2p13.1 [CytoView hg38]
ImmunoBaseENSG00000144034
Genome Data Viewer NCBITPRKB [Mapview hg19]  
OMIM608680   617731   
Gene and transcription
Genbank (Entrez)AF060921 AF151879 AI759966 AK097254 AK291071
RefSeq transcript (Entrez)NM_001330386 NM_001330387 NM_001330388 NM_001330389 NM_001330390 NM_001330391 NM_001330392 NM_016058
Consensus coding sequences : CCDS (NCBI)TPRKB
Gene ExpressionTPRKB [ NCBI-GEO ]   TPRKB [ EBI - ARRAY_EXPRESS ]   TPRKB [ SEEK ]   TPRKB [ MEM ]
Gene Expression Viewer (FireBrowse)TPRKB [ Firebrowse - Broad ]
GenevisibleExpression of TPRKB in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51002
GTEX Portal (Tissue expression)TPRKB
Human Protein AtlasENSG00000144034-TPRKB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3C4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3C4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3C4
PhosPhoSitePlusQ9Y3C4
Domains : Interpro (EBI)CGI121/TPRKB    CGI121/TPRKB_sf   
Domain families : Pfam (Sanger)CGI-121 (PF08617)   
Domain families : Pfam (NCBI)pfam08617   
Conserved Domain (NCBI)TPRKB
PDB (RSDB)3ENP   
PDB Europe3ENP   
PDB (PDBSum)3ENP   
PDB (IMB)3ENP   
Structural Biology KnowledgeBase3ENP   
SCOP (Structural Classification of Proteins)3ENP   
CATH (Classification of proteins structures)3ENP   
SuperfamilyQ9Y3C4
AlphaFold pdb e-kbQ9Y3C4   
Human Protein Atlas [tissue]ENSG00000144034-TPRKB [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3C4
IntAct (EBI)Q9Y3C4
BioGRIDTPRKB
STRING (EMBL)TPRKB
ZODIACTPRKB
Ontologies - Pathways
QuickGOQ9Y3C4
Ontology : AmiGOEKC/KEOPS complex  EKC/KEOPS complex  telomere maintenance via recombination  tRNA threonylcarbamoyladenosine modification  tRNA threonylcarbamoyladenosine modification  protein binding  nucleus  nucleus  cytoplasm  cytosol  cytosol  protein kinase binding  
Ontology : EGO-EBIEKC/KEOPS complex  EKC/KEOPS complex  telomere maintenance via recombination  tRNA threonylcarbamoyladenosine modification  tRNA threonylcarbamoyladenosine modification  protein binding  nucleus  nucleus  cytoplasm  cytosol  cytosol  protein kinase binding  
NDEx NetworkTPRKB
Atlas of Cancer Signalling NetworkTPRKB
Wikipedia pathwaysTPRKB
Orthology - Evolution
OrthoDB51002
GeneTree (enSembl)ENSG00000144034
Phylogenetic Trees/Animal Genes : TreeFamTPRKB
Homologs : HomoloGeneTPRKB
Homology/Alignments : Family Browser (UCSC)TPRKB
Gene fusions - Rearrangements
Fusion : QuiverTPRKB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTPRKB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPRKB
dbVarTPRKB
ClinVarTPRKB
MonarchTPRKB
1000_GenomesTPRKB 
Exome Variant ServerTPRKB
GNOMAD BrowserENSG00000144034
Varsome BrowserTPRKB
ACMGTPRKB variants
VarityQ9Y3C4
Genomic Variants (DGV)TPRKB [DGVbeta]
DECIPHERTPRKB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTPRKB 
Mutations
ICGC Data PortalTPRKB 
TCGA Data PortalTPRKB 
Broad Tumor PortalTPRKB
OASIS PortalTPRKB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTPRKB  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTPRKB
Mutations and Diseases : HGMDTPRKB
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTPRKB
DgiDB (Drug Gene Interaction Database)TPRKB
DoCM (Curated mutations)TPRKB
CIViC (Clinical Interpretations of Variants in Cancer)TPRKB
Cancer3DTPRKB
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608680    617731   
Orphanet
DisGeNETTPRKB
MedgenTPRKB
Genetic Testing Registry TPRKB
NextProtQ9Y3C4 [Medical]
GENETestsTPRKB
Target ValidationTPRKB
Huge Navigator TPRKB [HugePedia]
ClinGenTPRKB
Clinical trials, drugs, therapy
MyCancerGenomeTPRKB
Protein Interactions : CTDTPRKB
Pharm GKB GenePA143485660
PharosQ9Y3C4
Clinical trialTPRKB
Miscellaneous
canSAR (ICR)TPRKB
HarmonizomeTPRKB
DataMed IndexTPRKB
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTPRKB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:26:38 CEST 2021

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