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TPSB2 (tryptase beta 2 (gene/pseudogene))

Identity

Alias_namestryptase beta 2
Other aliasTPS2
tryptaseB
tryptaseC
HGNC (Hugo) TPSB2
LocusID (NCBI) 64499
Atlas_Id 75086
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 1228336 and ends at 1230184 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TPSB2   14120
Cards
Entrez_Gene (NCBI)TPSB2  64499  tryptase beta 2 (gene/pseudogene)
AliasesTPS2; tryptaseB; tryptaseC
GeneCards (Weizmann)TPSB2
Ensembl hg19 (Hinxton)ENSG00000197253 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197253 [Gene_View]  chr16:1228336-1230184 [Contig_View]  TPSB2 [Vega]
ICGC DataPortalENSG00000197253
TCGA cBioPortalTPSB2
AceView (NCBI)TPSB2
Genatlas (Paris)TPSB2
WikiGenes64499
SOURCE (Princeton)TPSB2
Genetics Home Reference (NIH)TPSB2
Genomic and cartography
GoldenPath hg38 (UCSC)TPSB2  -     chr16:1228336-1230184 -  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TPSB2  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblTPSB2 - 16p13.3 [CytoView hg19]  TPSB2 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBITPSB2 [Mapview hg19]  TPSB2 [Mapview hg38]
OMIM191081   
Gene and transcription
Genbank (Entrez)AK308208 BC028059 BC029356 FJ931119 FJ931120
RefSeq transcript (Entrez)NM_024164
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TPSB2
Cluster EST : UnigeneHs.592982 [ NCBI ]
CGAP (NCI)Hs.592982
Alternative Splicing GalleryENSG00000197253
Gene ExpressionTPSB2 [ NCBI-GEO ]   TPSB2 [ EBI - ARRAY_EXPRESS ]   TPSB2 [ SEEK ]   TPSB2 [ MEM ]
Gene Expression Viewer (FireBrowse)TPSB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64499
GTEX Portal (Tissue expression)TPSB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20231   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20231  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20231
Splice isoforms : SwissVarP20231
Catalytic activity : Enzyme3.4.21.59 [ Enzyme-Expasy ]   3.4.21.593.4.21.59 [ IntEnz-EBI ]   3.4.21.59 [ BRENDA ]   3.4.21.59 [ KEGG ]   
PhosPhoSitePlusP20231
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)TPSB2
DMDM Disease mutations64499
Blocks (Seattle)TPSB2
PDB (SRS)1A0L    1AAO    2BM2    2FPZ    2FS8    2FS9    2FWW    2FXR    2GDD    2ZA5    3V7T   
PDB (PDBSum)1A0L    1AAO    2BM2    2FPZ    2FS8    2FS9    2FWW    2FXR    2GDD    2ZA5    3V7T   
PDB (IMB)1A0L    1AAO    2BM2    2FPZ    2FS8    2FS9    2FWW    2FXR    2GDD    2ZA5    3V7T   
PDB (RSDB)1A0L    1AAO    2BM2    2FPZ    2FS8    2FS9    2FWW    2FXR    2GDD    2ZA5    3V7T   
Structural Biology KnowledgeBase1A0L    1AAO    2BM2    2FPZ    2FS8    2FS9    2FWW    2FXR    2GDD    2ZA5    3V7T   
SCOP (Structural Classification of Proteins)1A0L    1AAO    2BM2    2FPZ    2FS8    2FS9    2FWW    2FXR    2GDD    2ZA5    3V7T   
CATH (Classification of proteins structures)1A0L    1AAO    2BM2    2FPZ    2FS8    2FS9    2FWW    2FXR    2GDD    2ZA5    3V7T   
SuperfamilyP20231
Human Protein AtlasENSG00000197253
Peptide AtlasP20231
HPRD10277
IPIIPI00419942   
Protein Interaction databases
DIP (DOE-UCLA)P20231
IntAct (EBI)P20231
FunCoupENSG00000197253
BioGRIDTPSB2
STRING (EMBL)TPSB2
ZODIACTPSB2
Ontologies - Pathways
QuickGOP20231
Ontology : AmiGOserine-type endopeptidase activity  protein binding  extracellular region  proteolysis  serine-type peptidase activity  
Ontology : EGO-EBIserine-type endopeptidase activity  protein binding  extracellular region  proteolysis  serine-type peptidase activity  
NDEx NetworkTPSB2
Atlas of Cancer Signalling NetworkTPSB2
Wikipedia pathwaysTPSB2
Orthology - Evolution
OrthoDB64499
GeneTree (enSembl)ENSG00000197253
Phylogenetic Trees/Animal Genes : TreeFamTPSB2
HOVERGENP20231
HOGENOMP20231
Homologs : HomoloGeneTPSB2
Homology/Alignments : Family Browser (UCSC)TPSB2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTPSB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPSB2
dbVarTPSB2
ClinVarTPSB2
1000_GenomesTPSB2 
Exome Variant ServerTPSB2
ExAC (Exome Aggregation Consortium)TPSB2 (select the gene name)
Genetic variants : HAPMAP64499
Genomic Variants (DGV)TPSB2 [DGVbeta]
DECIPHERTPSB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTPSB2 
Mutations
ICGC Data PortalTPSB2 
TCGA Data PortalTPSB2 
Broad Tumor PortalTPSB2
OASIS PortalTPSB2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDTPSB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TPSB2
DgiDB (Drug Gene Interaction Database)TPSB2
DoCM (Curated mutations)TPSB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TPSB2 (select a term)
intoGenTPSB2
Cancer3DTPSB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM191081   
Orphanet
MedgenTPSB2
Genetic Testing Registry TPSB2
NextProtP20231 [Medical]
TSGene64499
GENETestsTPSB2
Target ValidationTPSB2
Huge Navigator TPSB2 [HugePedia]
snp3D : Map Gene to Disease64499
BioCentury BCIQTPSB2
ClinGenTPSB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64499
Chemical/Pharm GKB GenePA37846
Clinical trialTPSB2
Miscellaneous
canSAR (ICR)TPSB2 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTPSB2
EVEXTPSB2
GoPubMedTPSB2
iHOPTPSB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:46:50 CEST 2017

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