Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TPSG1 (tryptase gamma 1)

Identity

Alias (NCBI)PRSS31
TMT
trpA
HGNC (Hugo) TPSG1
HGNC Alias symbTMT
PRSS31
HGNC Alias nametryptase gamma II
 tryptase gamma I
LocusID (NCBI) 25823
Atlas_Id 51480
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 1221651 and ends at 1225268 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TPSG1   14134
Cards
Entrez_Gene (NCBI)TPSG1    tryptase gamma 1
AliasesPRSS31; TMT; trpA
GeneCards (Weizmann)TPSG1
Ensembl hg19 (Hinxton)ENSG00000116176 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116176 [Gene_View]  ENSG00000116176 [Sequence]  chr16:1221651-1225268 [Contig_View]  TPSG1 [Vega]
ICGC DataPortalENSG00000116176
TCGA cBioPortalTPSG1
AceView (NCBI)TPSG1
Genatlas (Paris)TPSG1
SOURCE (Princeton)TPSG1
Genetics Home Reference (NIH)TPSG1
Genomic and cartography
GoldenPath hg38 (UCSC)TPSG1  -     chr16:1221651-1225268 -  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TPSG1  -     16p13.3   [Description]    (hg19-Feb_2009)
GoldenPathTPSG1 - 16p13.3 [CytoView hg19]  TPSG1 - 16p13.3 [CytoView hg38]
ImmunoBaseENSG00000116176
Genome Data Viewer NCBITPSG1 [Mapview hg19]  
OMIM609341   
Gene and transcription
Genbank (Entrez)BE552396
RefSeq transcript (Entrez)NM_012467
Consensus coding sequences : CCDS (NCBI)TPSG1
Gene ExpressionTPSG1 [ NCBI-GEO ]   TPSG1 [ EBI - ARRAY_EXPRESS ]   TPSG1 [ SEEK ]   TPSG1 [ MEM ]
Gene Expression Viewer (FireBrowse)TPSG1 [ Firebrowse - Broad ]
GenevisibleExpression of TPSG1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25823
GTEX Portal (Tissue expression)TPSG1
Human Protein AtlasENSG00000116176-TPSG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRR2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRR2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRR2
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9NRR2
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1_PA_chymotrypsin    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)TPSG1
SuperfamilyQ9NRR2
AlphaFold pdb e-kbQ9NRR2   
Human Protein Atlas [tissue]ENSG00000116176-TPSG1 [tissue]
HPRD07160
Protein Interaction databases
DIP (DOE-UCLA)Q9NRR2
IntAct (EBI)Q9NRR2
BioGRIDTPSG1
STRING (EMBL)TPSG1
ZODIACTPSG1
Ontologies - Pathways
QuickGOQ9NRR2
Ontology : AmiGOserine-type endopeptidase activity  protein binding  extracellular space  integral component of plasma membrane  proteolysis  serine-type peptidase activity  
Ontology : EGO-EBIserine-type endopeptidase activity  protein binding  extracellular space  integral component of plasma membrane  proteolysis  serine-type peptidase activity  
NDEx NetworkTPSG1
Atlas of Cancer Signalling NetworkTPSG1
Wikipedia pathwaysTPSG1
Orthology - Evolution
OrthoDB25823
GeneTree (enSembl)ENSG00000116176
Phylogenetic Trees/Animal Genes : TreeFamTPSG1
Homologs : HomoloGeneTPSG1
Homology/Alignments : Family Browser (UCSC)TPSG1
Gene fusions - Rearrangements
Fusion : QuiverTPSG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTPSG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPSG1
dbVarTPSG1
ClinVarTPSG1
MonarchTPSG1
1000_GenomesTPSG1 
Exome Variant ServerTPSG1
GNOMAD BrowserENSG00000116176
Varsome BrowserTPSG1
ACMGTPSG1 variants
VarityQ9NRR2
Genomic Variants (DGV)TPSG1 [DGVbeta]
DECIPHERTPSG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTPSG1 
Mutations
ICGC Data PortalTPSG1 
TCGA Data PortalTPSG1 
Broad Tumor PortalTPSG1
OASIS PortalTPSG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTPSG1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTPSG1
Mutations and Diseases : HGMDTPSG1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTPSG1
DgiDB (Drug Gene Interaction Database)TPSG1
DoCM (Curated mutations)TPSG1
CIViC (Clinical Interpretations of Variants in Cancer)TPSG1
Cancer3DTPSG1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609341   
Orphanet
DisGeNETTPSG1
MedgenTPSG1
Genetic Testing Registry TPSG1
NextProtQ9NRR2 [Medical]
GENETestsTPSG1
Target ValidationTPSG1
Huge Navigator TPSG1 [HugePedia]
ClinGenTPSG1
Clinical trials, drugs, therapy
MyCancerGenomeTPSG1
Protein Interactions : CTDTPSG1
Pharm GKB GenePA37849
PharosQ9NRR2
Clinical trialTPSG1
Miscellaneous
canSAR (ICR)TPSG1
HarmonizomeTPSG1
DataMed IndexTPSG1
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTPSG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:36:03 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.