Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TPSG1 (tryptase gamma 1)

Identity

Alias_symbol (synonym)TMT
PRSS31
Other aliastrpA
HGNC (Hugo) TPSG1
LocusID (NCBI) 25823
Atlas_Id 51480
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 1221651 and ends at 1225254 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TPSG1   14134
Cards
Entrez_Gene (NCBI)TPSG1  25823  tryptase gamma 1
AliasesPRSS31; TMT; trpA
GeneCards (Weizmann)TPSG1
Ensembl hg19 (Hinxton)ENSG00000116176 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116176 [Gene_View]  chr16:1221651-1225254 [Contig_View]  TPSG1 [Vega]
ICGC DataPortalENSG00000116176
TCGA cBioPortalTPSG1
AceView (NCBI)TPSG1
Genatlas (Paris)TPSG1
WikiGenes25823
SOURCE (Princeton)TPSG1
Genetics Home Reference (NIH)TPSG1
Genomic and cartography
GoldenPath hg38 (UCSC)TPSG1  -     chr16:1221651-1225254 -  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TPSG1  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblTPSG1 - 16p13.3 [CytoView hg19]  TPSG1 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBITPSG1 [Mapview hg19]  TPSG1 [Mapview hg38]
OMIM609341   
Gene and transcription
Genbank (Entrez)BC172313 BE552396
RefSeq transcript (Entrez)NM_012467
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TPSG1
Cluster EST : UnigeneHs.592076 [ NCBI ]
CGAP (NCI)Hs.592076
Alternative Splicing GalleryENSG00000116176
Gene ExpressionTPSG1 [ NCBI-GEO ]   TPSG1 [ EBI - ARRAY_EXPRESS ]   TPSG1 [ SEEK ]   TPSG1 [ MEM ]
Gene Expression Viewer (FireBrowse)TPSG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25823
GTEX Portal (Tissue expression)TPSG1
Human Protein AtlasENSG00000116176-TPSG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRR2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRR2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRR2
Splice isoforms : SwissVarQ9NRR2
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusQ9NRR2
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)TPSG1
DMDM Disease mutations25823
Blocks (Seattle)TPSG1
SuperfamilyQ9NRR2
Human Protein Atlas [tissue]ENSG00000116176-TPSG1 [tissue]
Peptide AtlasQ9NRR2
HPRD07160
IPIIPI00018384   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRR2
IntAct (EBI)Q9NRR2
FunCoupENSG00000116176
BioGRIDTPSG1
STRING (EMBL)TPSG1
ZODIACTPSG1
Ontologies - Pathways
QuickGOQ9NRR2
Ontology : AmiGOserine-type endopeptidase activity  integral component of plasma membrane  proteolysis  serine-type peptidase activity  
Ontology : EGO-EBIserine-type endopeptidase activity  integral component of plasma membrane  proteolysis  serine-type peptidase activity  
NDEx NetworkTPSG1
Atlas of Cancer Signalling NetworkTPSG1
Wikipedia pathwaysTPSG1
Orthology - Evolution
OrthoDB25823
GeneTree (enSembl)ENSG00000116176
Phylogenetic Trees/Animal Genes : TreeFamTPSG1
HOVERGENQ9NRR2
HOGENOMQ9NRR2
Homologs : HomoloGeneTPSG1
Homology/Alignments : Family Browser (UCSC)TPSG1
Gene fusions - Rearrangements
Tumor Fusion PortalTPSG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTPSG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPSG1
dbVarTPSG1
ClinVarTPSG1
1000_GenomesTPSG1 
Exome Variant ServerTPSG1
ExAC (Exome Aggregation Consortium)ENSG00000116176
GNOMAD BrowserENSG00000116176
Genetic variants : HAPMAP25823
Genomic Variants (DGV)TPSG1 [DGVbeta]
DECIPHERTPSG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTPSG1 
Mutations
ICGC Data PortalTPSG1 
TCGA Data PortalTPSG1 
Broad Tumor PortalTPSG1
OASIS PortalTPSG1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTPSG1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTPSG1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TPSG1
DgiDB (Drug Gene Interaction Database)TPSG1
DoCM (Curated mutations)TPSG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TPSG1 (select a term)
intoGenTPSG1
Cancer3DTPSG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609341   
Orphanet
DisGeNETTPSG1
MedgenTPSG1
Genetic Testing Registry TPSG1
NextProtQ9NRR2 [Medical]
TSGene25823
GENETestsTPSG1
Target ValidationTPSG1
Huge Navigator TPSG1 [HugePedia]
snp3D : Map Gene to Disease25823
BioCentury BCIQTPSG1
ClinGenTPSG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25823
Chemical/Pharm GKB GenePA37849
Clinical trialTPSG1
Miscellaneous
canSAR (ICR)TPSG1 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTPSG1
EVEXTPSG1
GoPubMedTPSG1
iHOPTPSG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:39:26 CET 2017

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