TPSG1 (tryptase gamma 1)

2010-05-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
PRSS31,TMT,trpA

Other Information

Locus ID:

NCBI: 25823
MIM: 609341
HGNC: 14134
Ensembl: ENSG00000116176

Variants:

dbSNP: 25823
ClinVar: 25823
TCGA: ENSG00000116176
COSMIC: TPSG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116176ENST00000234798Q9NRR2

Expression (GTEx)

0
5
10
15
20

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
121949772002Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway.24
201269982010Mast cell tryptase promotes breast cancer migration and invasion.14

Citation

Dessen P

TPSG1 (tryptase gamma 1)

Atlas Genet Cytogenet Oncol Haematol. 2010-05-01

Online version: http://atlasgeneticsoncology.org/gene/51480/tpsg1