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TPST1 (tyrosylprotein sulfotransferase 1)

Identity

Alias (NCBI)TANGO13A
HGNC (Hugo) TPST1
HGNC Alias symbTANGO13A
HGNC Alias nametransport and golgi organization 13 homolog A (Drosophila)
LocusID (NCBI) 8460
Atlas_Id 53753
Location 7q11.21  [Link to chromosome band 7q11]
Location_base_pair Starts at 66205334 and ends at 66360443 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TPST1 (7q11.21) / APC (5q22.2)TPST1 (7q11.21) / TPST1 (7q11.21)WARS2 (1p12) / TPST1 (7q11.21)
ZSCAN25 (7q22.1) / TPST1 (7q11.21)WARS2 1p12 / TPST1 7q11.21ZNF498 TPST1 7q11.21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TPST1   12020
Cards
Entrez_Gene (NCBI)TPST1    tyrosylprotein sulfotransferase 1
AliasesTANGO13A
GeneCards (Weizmann)TPST1
Ensembl hg19 (Hinxton)ENSG00000169902 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169902 [Gene_View]  ENSG00000169902 [Sequence]  chr7:66205334-66360443 [Contig_View]  TPST1 [Vega]
ICGC DataPortalENSG00000169902
TCGA cBioPortalTPST1
AceView (NCBI)TPST1
Genatlas (Paris)TPST1
SOURCE (Princeton)TPST1
Genetics Home Reference (NIH)TPST1
Genomic and cartography
GoldenPath hg38 (UCSC)TPST1  -     chr7:66205334-66360443 +  7q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TPST1  -     7q11.21   [Description]    (hg19-Feb_2009)
GoldenPathTPST1 - 7q11.21 [CytoView hg19]  TPST1 - 7q11.21 [CytoView hg38]
ImmunoBaseENSG00000169902
Genome Data Viewer NCBITPST1 [Mapview hg19]  
OMIM603125   
Gene and transcription
Genbank (Entrez)AF038009 AI221558 AK095722 AK307053 AK313098
RefSeq transcript (Entrez)NM_003596
Consensus coding sequences : CCDS (NCBI)TPST1
Gene ExpressionTPST1 [ NCBI-GEO ]   TPST1 [ EBI - ARRAY_EXPRESS ]   TPST1 [ SEEK ]   TPST1 [ MEM ]
Gene Expression Viewer (FireBrowse)TPST1 [ Firebrowse - Broad ]
GenevisibleExpression of TPST1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8460
GTEX Portal (Tissue expression)TPST1
Human Protein AtlasENSG00000169902-TPST1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60507   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60507  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60507
PhosPhoSitePlusO60507
Domains : Interpro (EBI)P-loop_NTPase    TPST   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TPST1
PDB (RSDB)5WRI    5WRJ   
PDB Europe5WRI    5WRJ   
PDB (PDBSum)5WRI    5WRJ   
PDB (IMB)5WRI    5WRJ   
Structural Biology KnowledgeBase5WRI    5WRJ   
SCOP (Structural Classification of Proteins)5WRI    5WRJ   
CATH (Classification of proteins structures)5WRI    5WRJ   
SuperfamilyO60507
AlphaFold pdb e-kbO60507   
Human Protein Atlas [tissue]ENSG00000169902-TPST1 [tissue]
HPRD07216
Protein Interaction databases
DIP (DOE-UCLA)O60507
IntAct (EBI)O60507
BioGRIDTPST1
STRING (EMBL)TPST1
ZODIACTPST1
Ontologies - Pathways
QuickGOO60507
Ontology : AmiGOGolgi membrane  Golgi apparatus  peptidyl-tyrosine sulfation  peptidyl-tyrosine sulfation  peptidyl-tyrosine sulfation  inflammatory response  sulfotransferase activity  protein-tyrosine sulfotransferase activity  protein-tyrosine sulfotransferase activity  membrane  integral component of Golgi membrane  protein homodimerization activity  3'-phosphoadenosine 5'-phosphosulfate metabolic process  
Ontology : EGO-EBIGolgi membrane  Golgi apparatus  peptidyl-tyrosine sulfation  peptidyl-tyrosine sulfation  peptidyl-tyrosine sulfation  inflammatory response  sulfotransferase activity  protein-tyrosine sulfotransferase activity  protein-tyrosine sulfotransferase activity  membrane  integral component of Golgi membrane  protein homodimerization activity  3'-phosphoadenosine 5'-phosphosulfate metabolic process  
NDEx NetworkTPST1
Atlas of Cancer Signalling NetworkTPST1
Wikipedia pathwaysTPST1
Orthology - Evolution
OrthoDB8460
GeneTree (enSembl)ENSG00000169902
Phylogenetic Trees/Animal Genes : TreeFamTPST1
Homologs : HomoloGeneTPST1
Homology/Alignments : Family Browser (UCSC)TPST1
Gene fusions - Rearrangements
Fusion : MitelmanWARS2/TPST1 [1p12/7q11.21]  
Fusion : MitelmanZSCAN25/TPST1 [7q22.1/7q11.21]  
Fusion : QuiverTPST1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTPST1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPST1
dbVarTPST1
ClinVarTPST1
MonarchTPST1
1000_GenomesTPST1 
Exome Variant ServerTPST1
GNOMAD BrowserENSG00000169902
Varsome BrowserTPST1
ACMGTPST1 variants
VarityO60507
Genomic Variants (DGV)TPST1 [DGVbeta]
DECIPHERTPST1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTPST1 
Mutations
ICGC Data PortalTPST1 
TCGA Data PortalTPST1 
Broad Tumor PortalTPST1
OASIS PortalTPST1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTPST1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTPST1
Mutations and Diseases : HGMDTPST1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTPST1
DgiDB (Drug Gene Interaction Database)TPST1
DoCM (Curated mutations)TPST1
CIViC (Clinical Interpretations of Variants in Cancer)TPST1
Cancer3DTPST1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603125   
Orphanet
DisGeNETTPST1
MedgenTPST1
Genetic Testing Registry TPST1
NextProtO60507 [Medical]
GENETestsTPST1
Target ValidationTPST1
Huge Navigator TPST1 [HugePedia]
ClinGenTPST1
Clinical trials, drugs, therapy
MyCancerGenomeTPST1
Protein Interactions : CTDTPST1
Pharm GKB GenePA36699
PharosO60507
Clinical trialTPST1
Miscellaneous
canSAR (ICR)TPST1
HarmonizomeTPST1
DataMed IndexTPST1
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTPST1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:03 CEST 2021

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