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TPST2 (tyrosylprotein sulfotransferase 2)

Identity

Alias (NCBI)TANGO13B
TPST-2
HGNC (Hugo) TPST2
HGNC Alias symbTANGO13B
HGNC Alias nametransport and golgi organization 13 homolog B (Drosophila)
 protein-tyrosine sulfotransferase 2
LocusID (NCBI) 8459
Atlas_Id 54719
Location 22q12.1  [Link to chromosome band 22q12]
Location_base_pair Starts at 26521996 and ends at 26590132 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SFI1 (22q12.2) / TPST2 (22q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TPST2   12021
Cards
Entrez_Gene (NCBI)TPST2    tyrosylprotein sulfotransferase 2
AliasesTANGO13B; TPST-2
GeneCards (Weizmann)TPST2
Ensembl hg19 (Hinxton)ENSG00000128294 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128294 [Gene_View]  ENSG00000128294 [Sequence]  chr22:26521996-26590132 [Contig_View]  TPST2 [Vega]
ICGC DataPortalENSG00000128294
TCGA cBioPortalTPST2
AceView (NCBI)TPST2
Genatlas (Paris)TPST2
SOURCE (Princeton)TPST2
Genetics Home Reference (NIH)TPST2
Genomic and cartography
GoldenPath hg38 (UCSC)TPST2  -     chr22:26521996-26590132 -  22q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TPST2  -     22q12.1   [Description]    (hg19-Feb_2009)
GoldenPathTPST2 - 22q12.1 [CytoView hg19]  TPST2 - 22q12.1 [CytoView hg38]
ImmunoBaseENSG00000128294
Genome Data Viewer NCBITPST2 [Mapview hg19]  
OMIM603126   
Gene and transcription
Genbank (Entrez)AA531491 AF049891 AF061254 AJ006198 AK057171
RefSeq transcript (Entrez)NM_001008566 NM_001362922 NM_001362923 NM_003595
Consensus coding sequences : CCDS (NCBI)TPST2
Gene ExpressionTPST2 [ NCBI-GEO ]   TPST2 [ EBI - ARRAY_EXPRESS ]   TPST2 [ SEEK ]   TPST2 [ MEM ]
Gene Expression Viewer (FireBrowse)TPST2 [ Firebrowse - Broad ]
GenevisibleExpression of TPST2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8459
GTEX Portal (Tissue expression)TPST2
Human Protein AtlasENSG00000128294-TPST2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60704   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60704  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60704
PhosPhoSitePlusO60704
Domains : Interpro (EBI)P-loop_NTPase    TPST   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TPST2
PDB (RSDB)3AP1    3AP2    3AP3   
PDB Europe3AP1    3AP2    3AP3   
PDB (PDBSum)3AP1    3AP2    3AP3   
PDB (IMB)3AP1    3AP2    3AP3   
Structural Biology KnowledgeBase3AP1    3AP2    3AP3   
SCOP (Structural Classification of Proteins)3AP1    3AP2    3AP3   
CATH (Classification of proteins structures)3AP1    3AP2    3AP3   
SuperfamilyO60704
AlphaFold pdb e-kbO60704   
Human Protein Atlas [tissue]ENSG00000128294-TPST2 [tissue]
HPRD07217
Protein Interaction databases
DIP (DOE-UCLA)O60704
IntAct (EBI)O60704
BioGRIDTPST2
STRING (EMBL)TPST2
ZODIACTPST2
Ontologies - Pathways
QuickGOO60704
Ontology : AmiGOGolgi membrane  endoplasmic reticulum  Golgi apparatus  peptidyl-tyrosine sulfation  peptidyl-tyrosine sulfation  peptidyl-tyrosine sulfation  sulfotransferase activity  protein-tyrosine sulfotransferase activity  protein-tyrosine sulfotransferase activity  integral component of membrane  protein homodimerization activity  3'-phosphoadenosine 5'-phosphosulfate metabolic process  
Ontology : EGO-EBIGolgi membrane  endoplasmic reticulum  Golgi apparatus  peptidyl-tyrosine sulfation  peptidyl-tyrosine sulfation  peptidyl-tyrosine sulfation  sulfotransferase activity  protein-tyrosine sulfotransferase activity  protein-tyrosine sulfotransferase activity  integral component of membrane  protein homodimerization activity  3'-phosphoadenosine 5'-phosphosulfate metabolic process  
NDEx NetworkTPST2
Atlas of Cancer Signalling NetworkTPST2
Wikipedia pathwaysTPST2
Orthology - Evolution
OrthoDB8459
GeneTree (enSembl)ENSG00000128294
Phylogenetic Trees/Animal Genes : TreeFamTPST2
Homologs : HomoloGeneTPST2
Homology/Alignments : Family Browser (UCSC)TPST2
Gene fusions - Rearrangements
Fusion : MitelmanSFI1/TPST2 [22q12.2/22q12.1]  
Fusion : QuiverTPST2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTPST2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TPST2
dbVarTPST2
ClinVarTPST2
MonarchTPST2
1000_GenomesTPST2 
Exome Variant ServerTPST2
GNOMAD BrowserENSG00000128294
Varsome BrowserTPST2
ACMGTPST2 variants
VarityO60704
Genomic Variants (DGV)TPST2 [DGVbeta]
DECIPHERTPST2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTPST2 
Mutations
ICGC Data PortalTPST2 
TCGA Data PortalTPST2 
Broad Tumor PortalTPST2
OASIS PortalTPST2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTPST2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTPST2
Mutations and Diseases : HGMDTPST2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTPST2
DgiDB (Drug Gene Interaction Database)TPST2
DoCM (Curated mutations)TPST2
CIViC (Clinical Interpretations of Variants in Cancer)TPST2
Cancer3DTPST2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603126   
Orphanet
DisGeNETTPST2
MedgenTPST2
Genetic Testing Registry TPST2
NextProtO60704 [Medical]
GENETestsTPST2
Target ValidationTPST2
Huge Navigator TPST2 [HugePedia]
ClinGenTPST2
Clinical trials, drugs, therapy
MyCancerGenomeTPST2
Protein Interactions : CTDTPST2
Pharm GKB GenePA36700
PharosO60704
Clinical trialTPST2
Miscellaneous
canSAR (ICR)TPST2
HarmonizomeTPST2
DataMed IndexTPST2
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTPST2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:04 CEST 2021

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