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TRA2A (transformer 2 alpha homolog)

Identity

Alias_namestransformer 2 alpha homolog (Drosophila)
Alias_symbol (synonym)htra-2-alpha
tra2a
AWMS1
Other aliasHSU53209
HGNC (Hugo) TRA2A
LocusID (NCBI) 29896
Atlas_Id 52439
Location 7p15.3  [Link to chromosome band 7p15]
Location_base_pair Starts at 23544401 and ends at 23571660 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GSN (9q33.2) / TRA2A (7p15.3)MPLKIP (7p14.1) / TRA2A (7p15.3)TRA2A (7p15.3) / CBX3 (7p15.2)
TRA2A (7p15.3) / CENPO (2p23.3)TRA2A (7p15.3) / DNAH11 (7p15.3)TRA2A (7p15.3) / EPDR1 (7p14.1)
TRA2A (7p15.3) / HECW1 (7p14.1)TRA2A (7p15.3) / HMGB2 (4q34.1)TRA2A (7p15.3) / THADA (2p21)
TRA2A (7p15.3) / TRA2A (7p15.3)C7orf11 TRA2A 7p15.3GSN 9q33.2 / TRA2A 7p15.3
TRA2A 7p15.3 / EPDR1 7p14.1TRA2A 7p15.3 / HECW1 7p14.1TRA2A 7p15.3 / THADA 2p21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRA2A   16645
Cards
Entrez_Gene (NCBI)TRA2A  29896  transformer 2 alpha homolog
AliasesAWMS1; HSU53209
GeneCards (Weizmann)TRA2A
Ensembl hg19 (Hinxton)ENSG00000164548 [Gene_View]  chr7:23544401-23571660 [Contig_View]  TRA2A [Vega]
Ensembl hg38 (Hinxton)ENSG00000164548 [Gene_View]  chr7:23544401-23571660 [Contig_View]  TRA2A [Vega]
ICGC DataPortalENSG00000164548
TCGA cBioPortalTRA2A
AceView (NCBI)TRA2A
Genatlas (Paris)TRA2A
WikiGenes29896
SOURCE (Princeton)TRA2A
Genetics Home Reference (NIH)TRA2A
Genomic and cartography
GoldenPath hg19 (UCSC)TRA2A  -     chr7:23544401-23571660 -  7p15.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TRA2A  -     7p15.3   [Description]    (hg38-Dec_2013)
EnsemblTRA2A - 7p15.3 [CytoView hg19]  TRA2A - 7p15.3 [CytoView hg38]
Mapping of homologs : NCBITRA2A [Mapview hg19]  TRA2A [Mapview hg38]
OMIM602718   
Gene and transcription
Genbank (Entrez)AB052759 AB097048 AK298815 AK300565 AK300741
RefSeq transcript (Entrez)NM_001282757 NM_001282758 NM_001282759 NM_013293
RefSeq genomic (Entrez)NC_000007 NC_018918 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)TRA2A
Cluster EST : UnigeneHs.445652 [ NCBI ]
CGAP (NCI)Hs.445652
Alternative Splicing GalleryENSG00000164548
Gene ExpressionTRA2A [ NCBI-GEO ]   TRA2A [ EBI - ARRAY_EXPRESS ]   TRA2A [ SEEK ]   TRA2A [ MEM ]
Gene Expression Viewer (FireBrowse)TRA2A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29896
GTEX Portal (Tissue expression)TRA2A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13595   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13595  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13595
Splice isoforms : SwissVarQ13595
PhosPhoSitePlusQ13595
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)TRA2A
DMDM Disease mutations29896
Blocks (Seattle)TRA2A
SuperfamilyQ13595
Human Protein AtlasENSG00000164548
Peptide AtlasQ13595
HPRD04096
IPIIPI00013891   IPI00220447   IPI01014274   IPI00217517   IPI00917062   
Protein Interaction databases
DIP (DOE-UCLA)Q13595
IntAct (EBI)Q13595
FunCoupENSG00000164548
BioGRIDTRA2A
STRING (EMBL)TRA2A
ZODIACTRA2A
Ontologies - Pathways
QuickGOQ13595
Ontology : AmiGOnucleotide binding  mRNA splicing, via spliceosome  nucleus  nucleolus  intracellular membrane-bounded organelle  poly(A) RNA binding  
Ontology : EGO-EBInucleotide binding  mRNA splicing, via spliceosome  nucleus  nucleolus  intracellular membrane-bounded organelle  poly(A) RNA binding  
Pathways : KEGGSpliceosome   
NDEx NetworkTRA2A
Atlas of Cancer Signalling NetworkTRA2A
Wikipedia pathwaysTRA2A
Orthology - Evolution
OrthoDB29896
GeneTree (enSembl)ENSG00000164548
Phylogenetic Trees/Animal Genes : TreeFamTRA2A
HOVERGENQ13595
HOGENOMQ13595
Homologs : HomoloGeneTRA2A
Homology/Alignments : Family Browser (UCSC)TRA2A
Gene fusions - Rearrangements
Fusion : MitelmanGSN/TRA2A [9q33.2/7p15.3]  [t(7;9)(p15;q33)]  
Fusion : MitelmanMPLKIP/TRA2A [7p14.1/7p15.3]  [t(7;7)(p14;p15)]  
Fusion : MitelmanTRA2A/EPDR1 [7p15.3/7p14.1]  [t(7;7)(p14;p15)]  
Fusion : MitelmanTRA2A/HECW1 [7p15.3/7p14.1]  [t(7;7)(p14;p15)]  
Fusion : MitelmanTRA2A/THADA [7p15.3/2p21]  [t(2;7)(p21;p15)]  
Fusion: TCGAC7orf11 TRA2A 7p15.3 BRCA
Fusion: TCGAGSN 9q33.2 TRA2A 7p15.3 PRAD
Fusion: TCGATRA2A 7p15.3 EPDR1 7p14.1 LUAD
Fusion: TCGATRA2A 7p15.3 HECW1 7p14.1 BRCA
Fusion: TCGATRA2A 7p15.3 THADA 2p21 THCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRA2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRA2A
dbVarTRA2A
ClinVarTRA2A
1000_GenomesTRA2A 
Exome Variant ServerTRA2A
ExAC (Exome Aggregation Consortium)TRA2A (select the gene name)
Genetic variants : HAPMAP29896
Genomic Variants (DGV)TRA2A [DGVbeta]
DECIPHER (Syndromes)7:23544401-23571660  ENSG00000164548
CONAN: Copy Number AnalysisTRA2A 
Mutations
ICGC Data PortalTRA2A 
TCGA Data PortalTRA2A 
Broad Tumor PortalTRA2A
OASIS PortalTRA2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRA2A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRA2A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRA2A
DgiDB (Drug Gene Interaction Database)TRA2A
DoCM (Curated mutations)TRA2A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRA2A (select a term)
intoGenTRA2A
Cancer3DTRA2A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602718   
Orphanet
MedgenTRA2A
Genetic Testing Registry TRA2A
NextProtQ13595 [Medical]
TSGene29896
GENETestsTRA2A
Huge Navigator TRA2A [HugePedia]
snp3D : Map Gene to Disease29896
BioCentury BCIQTRA2A
ClinGenTRA2A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29896
Chemical/Pharm GKB GenePA164726707
Clinical trialTRA2A
Miscellaneous
canSAR (ICR)TRA2A (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRA2A
EVEXTRA2A
GoPubMedTRA2A
iHOPTRA2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:32:06 CET 2017

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