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TRABD2A (TraB domain containing 2A)

Identity

Alias (NCBI)C2orf89
TIKI1
HGNC (Hugo) TRABD2A
HGNC Alias symbTIKI1
HGNC Previous nameC2orf89
HGNC Previous namechromosome 2 open reading frame 89
LocusID (NCBI) 129293
Atlas_Id 75096
Location 2p11.2  [Link to chromosome band 2p11]
Location_base_pair Starts at 84835919 and ends at 84881084 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRABD2A   27013
Cards
Entrez_Gene (NCBI)TRABD2A    TraB domain containing 2A
AliasesC2orf89; TIKI1
GeneCards (Weizmann)TRABD2A
Ensembl hg19 (Hinxton)ENSG00000186854 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186854 [Gene_View]  ENSG00000186854 [Sequence]  chr2:84835919-84881084 [Contig_View]  TRABD2A [Vega]
ICGC DataPortalENSG00000186854
TCGA cBioPortalTRABD2A
AceView (NCBI)TRABD2A
Genatlas (Paris)TRABD2A
SOURCE (Princeton)TRABD2A
Genetics Home Reference (NIH)TRABD2A
Genomic and cartography
GoldenPath hg38 (UCSC)TRABD2A  -     chr2:84835919-84881084 -  2p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRABD2A  -     2p11.2   [Description]    (hg19-Feb_2009)
GoldenPathTRABD2A - 2p11.2 [CytoView hg19]  TRABD2A - 2p11.2 [CytoView hg38]
ImmunoBaseENSG00000186854
Genome Data Viewer NCBITRABD2A [Mapview hg19]  
OMIM614912   
Gene and transcription
Genbank (Entrez)AK128325 AK296608 AK309615 BC049209 BC051789
RefSeq transcript (Entrez)NM_001080824 NM_001277053 NM_001307978
Consensus coding sequences : CCDS (NCBI)TRABD2A
Gene ExpressionTRABD2A [ NCBI-GEO ]   TRABD2A [ EBI - ARRAY_EXPRESS ]   TRABD2A [ SEEK ]   TRABD2A [ MEM ]
Gene Expression Viewer (FireBrowse)TRABD2A [ Firebrowse - Broad ]
GenevisibleExpression of TRABD2A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)129293
GTEX Portal (Tissue expression)TRABD2A
Human Protein AtlasENSG00000186854-TRABD2A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86V40   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86V40  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86V40
Catalytic activity : Enzyme3.4.-.- [ Enzyme-Expasy ]   3.4.-.-3.4.-.- [ IntEnz-EBI ]   3.4.-.- [ BRENDA ]   3.4.-.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ86V40
Domains : Interpro (EBI)TIKI1/2-like    TraB/PrgY/gumN_fam   
Domain families : Pfam (Sanger)TraB (PF01963)   
Domain families : Pfam (NCBI)pfam01963   
Conserved Domain (NCBI)TRABD2A
SuperfamilyQ86V40
AlphaFold pdb e-kbQ86V40   
Human Protein Atlas [tissue]ENSG00000186854-TRABD2A [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q86V40
IntAct (EBI)Q86V40
BioGRIDTRABD2A
STRING (EMBL)TRABD2A
ZODIACTRABD2A
Ontologies - Pathways
QuickGOQ86V40
Ontology : AmiGOendopeptidase activity  metalloendopeptidase activity  metalloendopeptidase activity  metalloendopeptidase activity  integral component of plasma membrane  integral component of plasma membrane  proteolysis  membrane  Wnt signaling pathway  Wnt-protein binding  Wnt-protein binding  negative regulation of Wnt signaling pathway  negative regulation of Wnt signaling pathway  integral component of organelle membrane  integral component of organelle membrane  positive regulation of protein-containing complex assembly  metal ion binding  head development  positive regulation of protein oxidation  
Ontology : EGO-EBIendopeptidase activity  metalloendopeptidase activity  metalloendopeptidase activity  metalloendopeptidase activity  integral component of plasma membrane  integral component of plasma membrane  proteolysis  membrane  Wnt signaling pathway  Wnt-protein binding  Wnt-protein binding  negative regulation of Wnt signaling pathway  negative regulation of Wnt signaling pathway  integral component of organelle membrane  integral component of organelle membrane  positive regulation of protein-containing complex assembly  metal ion binding  head development  positive regulation of protein oxidation  
NDEx NetworkTRABD2A
Atlas of Cancer Signalling NetworkTRABD2A
Wikipedia pathwaysTRABD2A
Orthology - Evolution
OrthoDB129293
GeneTree (enSembl)ENSG00000186854
Phylogenetic Trees/Animal Genes : TreeFamTRABD2A
Homologs : HomoloGeneTRABD2A
Homology/Alignments : Family Browser (UCSC)TRABD2A
Gene fusions - Rearrangements
Fusion : QuiverTRABD2A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRABD2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRABD2A
dbVarTRABD2A
ClinVarTRABD2A
MonarchTRABD2A
1000_GenomesTRABD2A 
Exome Variant ServerTRABD2A
GNOMAD BrowserENSG00000186854
Varsome BrowserTRABD2A
ACMGTRABD2A variants
VarityQ86V40
Genomic Variants (DGV)TRABD2A [DGVbeta]
DECIPHERTRABD2A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRABD2A 
Mutations
ICGC Data PortalTRABD2A 
TCGA Data PortalTRABD2A 
Broad Tumor PortalTRABD2A
OASIS PortalTRABD2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRABD2A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRABD2A
Mutations and Diseases : HGMDTRABD2A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRABD2A
DgiDB (Drug Gene Interaction Database)TRABD2A
DoCM (Curated mutations)TRABD2A
CIViC (Clinical Interpretations of Variants in Cancer)TRABD2A
Cancer3DTRABD2A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614912   
Orphanet
DisGeNETTRABD2A
MedgenTRABD2A
Genetic Testing Registry TRABD2A
NextProtQ86V40 [Medical]
GENETestsTRABD2A
Target ValidationTRABD2A
Huge Navigator TRABD2A [HugePedia]
ClinGenTRABD2A
Clinical trials, drugs, therapy
MyCancerGenomeTRABD2A
Protein Interactions : CTDTRABD2A
Pharm GKB GenePA165696373
PharosQ86V40
Clinical trialTRABD2A
Miscellaneous
canSAR (ICR)TRABD2A
HarmonizomeTRABD2A
DataMed IndexTRABD2A
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRABD2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:26:41 CEST 2021

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