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TRADD (TNFRSF1A-associated via death domain)

Identity

Other namesHs.89862
HGNC (Hugo) TRADD
LocusID (NCBI) 8717
Atlas_Id 42685
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 67188089 and ends at 67193812 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TRADD (16q22.1) / B3GNT9 (16q22.1)TRADD (16q22.1) / SLC12A1 (15q21.1)TRADD 16q22.1 / SLC12A1 15q21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRADD   12030
Cards
Entrez_Gene (NCBI)TRADD  8717  TNFRSF1A-associated via death domain
AliasesHs.89862
GeneCards (Weizmann)TRADD
Ensembl hg19 (Hinxton)ENSG00000102871 [Gene_View]  chr16:67188089-67193812 [Contig_View]  TRADD [Vega]
Ensembl hg38 (Hinxton)ENSG00000102871 [Gene_View]  chr16:67188089-67193812 [Contig_View]  TRADD [Vega]
ICGC DataPortalENSG00000102871
TCGA cBioPortalTRADD
AceView (NCBI)TRADD
Genatlas (Paris)TRADD
WikiGenes8717
SOURCE (Princeton)TRADD
Genomic and cartography
GoldenPath hg19 (UCSC)TRADD  -     chr16:67188089-67193812 -  16q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TRADD  -     16q22.1   [Description]    (hg38-Dec_2013)
EnsemblTRADD - 16q22.1 [CytoView hg19]  TRADD - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBITRADD [Mapview hg19]  TRADD [Mapview hg38]
OMIM603500   
Gene and transcription
Genbank (Entrez)AK090673 AK301593 AK315654 BC004491 BG717460
RefSeq transcript (Entrez)NM_003789 NM_153425
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)TRADD
Cluster EST : UnigeneHs.460996 [ NCBI ]
CGAP (NCI)Hs.460996
Alternative Splicing GalleryENSG00000102871
Gene ExpressionTRADD [ NCBI-GEO ]   TRADD [ EBI - ARRAY_EXPRESS ]   TRADD [ SEEK ]   TRADD [ MEM ]
Gene Expression Viewer (FireBrowse)TRADD [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8717
GTEX Portal (Tissue expression)TRADD
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15628 (Uniprot)
NextProtQ15628  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15628
Splice isoforms : SwissVarQ15628 (Swissvar)
PhosPhoSitePlusQ15628
Domaine pattern : Prosite (Expaxy)DEATH_DOMAIN (PS50017)   
Domains : Interpro (EBI)DEATH-like_dom    Death_domain    TRADD_N   
Domain families : Pfam (Sanger)Death (PF00531)    TRADD_N (PF09034)   
Domain families : Pfam (NCBI)pfam00531    pfam09034   
Domain families : Smart (EMBL)DEATH (SM00005)  
Domain structure : Prodom (Prabi Lyon)TRADD_N (PD182470)   
DMDM Disease mutations8717
Blocks (Seattle)TRADD
PDB (SRS)1F2H    1F3V   
PDB (PDBSum)1F2H    1F3V   
PDB (IMB)1F2H    1F3V   
PDB (RSDB)1F2H    1F3V   
Structural Biology KnowledgeBase1F2H    1F3V   
SCOP (Structural Classification of Proteins)1F2H    1F3V   
CATH (Classification of proteins structures)1F2H    1F3V   
SuperfamilyQ15628
Human Protein AtlasENSG00000102871
Peptide AtlasQ15628
HPRD04610
IPIIPI00018744   IPI00910743   
Protein Interaction databases
DIP (DOE-UCLA)Q15628
IntAct (EBI)Q15628
FunCoupENSG00000102871
BioGRIDTRADD
STRING (EMBL)TRADD
ZODIACTRADD
Ontologies - Pathways
QuickGOQ15628
Ontology : AmiGOsignal transducer activity  tumor necrosis factor receptor binding  protein binding  nucleus  cytoplasm  cytosol  cytoskeleton  plasma membrane  apoptotic process  activation of cysteine-type endopeptidase activity involved in apoptotic process  signal transduction  I-kappaB kinase/NF-kappaB signaling  extrinsic apoptotic signaling pathway via death domain receptors  regulation of tumor necrosis factor-mediated signaling pathway  regulation of necrotic cell death  kinase binding  death-inducing signaling complex  protein complex binding  tumor necrosis factor-mediated signaling pathway  identical protein binding  positive regulation of apoptotic process  positive regulation of I-kappaB kinase/NF-kappaB signaling  receptor complex  membrane raft  positive regulation of NF-kappaB transcription factor activity  protein heterooligomerization  positive regulation of hair follicle development  binding, bridging  death domain binding  death-inducing signaling complex assembly  extrinsic apoptotic signaling pathway  extrinsic apoptotic signaling pathway  activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway  regulation of extrinsic apoptotic signaling pathway via death domain receptors  negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  
Ontology : EGO-EBIsignal transducer activity  tumor necrosis factor receptor binding  protein binding  nucleus  cytoplasm  cytosol  cytoskeleton  plasma membrane  apoptotic process  activation of cysteine-type endopeptidase activity involved in apoptotic process  signal transduction  I-kappaB kinase/NF-kappaB signaling  extrinsic apoptotic signaling pathway via death domain receptors  regulation of tumor necrosis factor-mediated signaling pathway  regulation of necrotic cell death  kinase binding  death-inducing signaling complex  protein complex binding  tumor necrosis factor-mediated signaling pathway  identical protein binding  positive regulation of apoptotic process  positive regulation of I-kappaB kinase/NF-kappaB signaling  receptor complex  membrane raft  positive regulation of NF-kappaB transcription factor activity  protein heterooligomerization  positive regulation of hair follicle development  binding, bridging  death domain binding  death-inducing signaling complex assembly  extrinsic apoptotic signaling pathway  extrinsic apoptotic signaling pathway  activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway  regulation of extrinsic apoptotic signaling pathway via death domain receptors  negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  
Pathways : BIOCARTAHIV-I Nef: negative effector of Fas and TNF [Genes]    Induction of apoptosis through DR3 and DR4/5 Death Receptors [Genes]    Ceramide Signaling Pathway [Genes]    TNFR1 Signaling Pathway [Genes]    MAPKinase Signaling Pathway [Genes]    NF-kB Signaling Pathway [Genes]    Acetylation and Deacetylation of RelA in The Nucleus [Genes]    p38 MAPK Signaling Pathway [Genes]    TNF/Stress Related Signaling [Genes]    SODD/TNFR1 Signaling Pathway [Genes]   
Pathways : KEGGNF-kappa B signaling pathway    Apoptosis    RIG-I-like receptor signaling pathway    TNF signaling pathway    Adipocytokine signaling pathway    Tuberculosis    Hepatitis C    Epstein-Barr virus infection    Viral carcinogenesis   
NDEx Network
Atlas of Cancer Signalling NetworkTRADD
Wikipedia pathwaysTRADD
Orthology - Evolution
OrthoDB8717
GeneTree (enSembl)ENSG00000102871
Phylogenetic Trees/Animal Genes : TreeFamTRADD
Homologs : HomoloGeneTRADD
Homology/Alignments : Family Browser (UCSC)TRADD
Gene fusions - Rearrangements
Fusion: TCGATRADD 16q22.1 SLC12A1 15q21.1 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerTRADD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRADD
dbVarTRADD
ClinVarTRADD
1000_GenomesTRADD 
Exome Variant ServerTRADD
ExAC (Exome Aggregation Consortium)TRADD (select the gene name)
Genetic variants : HAPMAP8717
Genomic Variants (DGV)TRADD [DGVbeta]
Mutations
ICGC Data PortalTRADD 
TCGA Data PortalTRADD 
Broad Tumor PortalTRADD
OASIS PortalTRADD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRADD 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRADD
DgiDB (Drug Gene Interaction Database)TRADD
DoCM (Curated mutations)TRADD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRADD (select a term)
intoGenTRADD
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:67188089-67193812  ENSG00000102871
CONAN: Copy Number AnalysisTRADD 
Mutations and Diseases : HGMDTRADD
OMIM603500   
MedgenTRADD
Genetic Testing Registry TRADD
NextProtQ15628 [Medical]
TSGene8717
GENETestsTRADD
Huge Navigator TRADD [HugePedia]
snp3D : Map Gene to Disease8717
BioCentury BCIQTRADD
ClinGenTRADD
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8717
Chemical/Pharm GKB GenePA36707
Clinical trialTRADD
Miscellaneous
canSAR (ICR)TRADD (select the gene name)
Probes
Litterature
PubMed126 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRADD
EVEXTRADD
GoPubMedTRADD
iHOPTRADD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 9 19:12:50 CEST 2016

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