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TRADD (TNFRSF1A-associated via death domain)

Identity

Other namesHs.89862
HGNC (Hugo) TRADD
LocusID (NCBI) 8717
Location 16q22.1
Location_base_pair Starts at 67188089 and ends at 67193812 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)TRADD   12030
Cards
Entrez_Gene (NCBI)TRADD  8717  TNFRSF1A-associated via death domain
GeneCards (Weizmann)TRADD
Ensembl (Hinxton) [Gene_View]  chr16:67188089-67193812 [Contig_View]  TRADD [Vega]
cBioPortalTRADD
AceView (NCBI)TRADD
Genatlas (Paris)TRADD
WikiGenes8717
SOURCE (Princeton)NM_003789 NM_153425
Genomic and cartography
GoldenPath (UCSC)TRADD  -  16q22.1   chr16:67188089-67193812 -  16q22.1   [Description]    (hg19-Feb_2009)
EnsemblTRADD - 16q22.1 [CytoView]
Mapping of homologs : NCBITRADD [Mapview]
OMIM603500   
Gene and transcription
Genbank (Entrez)AK090673 AK301593 AK315654 BC004491 BG717460
RefSeq transcript (Entrez)NM_003789 NM_153425
RefSeq genomic (Entrez)AC_000148 NC_000016 NC_018927 NT_010498 NW_001838290 NW_004929402
Consensus coding sequences : CCDS (NCBI)TRADD
Cluster EST : UnigeneHs.460996 [ NCBI ]
CGAP (NCI)Hs.460996
Alternative Splicing : Fast-db (Paris)GSHG0011904
Gene ExpressionTRADD [ NCBI-GEO ]     TRADD [ SEEK ]   TRADD [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15628 (Uniprot)
NextProtQ15628  [Medical]
With graphics : InterProQ15628
Splice isoforms : SwissVarQ15628 (Swissvar)
Domaine pattern : Prosite (Expaxy)DEATH_DOMAIN (PS50017)   
Domains : Interpro (EBI)DEATH-like_dom [organisation]   Death_domain [organisation]   TRADD_N [organisation]  
Related proteins : CluSTrQ15628
Domain families : Pfam (Sanger)Death (PF00531)    TRADD_N (PF09034)   
Domain families : Pfam (NCBI)pfam00531    pfam09034   
Domain families : Smart (EMBL)DEATH (SM00005)  
Domain structure : Prodom (Prabi Lyon)TRADD_N (PD182470)   
DMDM Disease mutations8717
Blocks (Seattle)Q15628
PDB (SRS)1F2H    1F3V   
PDB (PDBSum)1F2H    1F3V   
PDB (IMB)1F2H    1F3V   
PDB (RSDB)1F2H    1F3V   
Peptide AtlasQ15628
HPRD04610
IPIIPI00018744   IPI00910743   
Protein Interaction databases
DIP (DOE-UCLA)Q15628
IntAct (EBI)Q15628
BioGRIDTRADD
InParanoidQ15628
Interologous Interaction database Q15628
IntegromeDBTRADD
STRING (EMBL)TRADD
Ontologies - Pathways
Ontology : AmiGOsignal transducer activity  tumor necrosis factor receptor binding  protein binding  nucleus  cytoplasm  cytosol  cytoskeleton  apoptotic process  activation of cysteine-type endopeptidase activity involved in apoptotic process  signal transduction  extrinsic apoptotic signaling pathway via death domain receptors  kinase binding  death-inducing signaling complex  protein complex binding  tumor necrosis factor-mediated signaling pathway  identical protein binding  positive regulation of apoptotic process  positive regulation of I-kappaB kinase/NF-kappaB signaling  receptor complex  membrane raft  positive regulation of NF-kappaB transcription factor activity  protein heterooligomerization  positive regulation of hair follicle development  binding, bridging  death domain binding  apoptotic signaling pathway  extrinsic apoptotic signaling pathway  extrinsic apoptotic signaling pathway  regulation of extrinsic apoptotic signaling pathway in absence of ligand  
Ontology : EGO-EBIsignal transducer activity  tumor necrosis factor receptor binding  protein binding  nucleus  cytoplasm  cytosol  cytoskeleton  apoptotic process  activation of cysteine-type endopeptidase activity involved in apoptotic process  signal transduction  extrinsic apoptotic signaling pathway via death domain receptors  kinase binding  death-inducing signaling complex  protein complex binding  tumor necrosis factor-mediated signaling pathway  identical protein binding  positive regulation of apoptotic process  positive regulation of I-kappaB kinase/NF-kappaB signaling  receptor complex  membrane raft  positive regulation of NF-kappaB transcription factor activity  protein heterooligomerization  positive regulation of hair follicle development  binding, bridging  death domain binding  apoptotic signaling pathway  extrinsic apoptotic signaling pathway  extrinsic apoptotic signaling pathway  regulation of extrinsic apoptotic signaling pathway in absence of ligand  
Pathways : BIOCARTAHIV-I Nef: negative effector of Fas and TNF [Genes]    Induction of apoptosis through DR3 and DR4/5 Death Receptors [Genes]    Ceramide Signaling Pathway [Genes]    TNFR1 Signaling Pathway [Genes]    MAPKinase Signaling Pathway [Genes]    NF-kB Signaling Pathway [Genes]    Acetylation and Deacetylation of RelA in The Nucleus [Genes]    p38 MAPK Signaling Pathway [Genes]    TNF/Stress Related Signaling [Genes]    SODD/TNFR1 Signaling Pathway [Genes]   
Pathways : KEGGNF-kappa B signaling pathway    Apoptosis    RIG-I-like receptor signaling pathway    TNF signaling pathway    Adipocytokine signaling pathway    Tuberculosis    Hepatitis C    Epstein-Barr virus infection    Viral carcinogenesis   
Protein Interaction DatabaseTRADD
Wikipedia pathwaysTRADD
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TRADD
snp3D : Map Gene to Disease8717
SNP (GeneSNP Utah)TRADD
SNP : HGBaseTRADD
Genetic variants : HAPMAPTRADD
Exome VariantTRADD
1000_GenomesTRADD 
Somatic Mutations in Cancer : COSMICTRADD 
CONAN: Copy Number AnalysisTRADD 
Mutations and Diseases : HGMDTRADD
Mutations and Diseases : intOGenTRADD
Genomic VariantsTRADD  TRADD [DGVbeta]
dbVarTRADD
ClinVarTRADD
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM603500   
MedgenTRADD
GENETestsTRADD
Disease Genetic AssociationTRADD
Huge Navigator TRADD [HugePedia]  TRADD [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneTRADD
Homology/Alignments : Family Browser (UCSC)TRADD
Phylogenetic Trees/Animal Genes : TreeFamTRADD
Chemical/Protein Interactions : CTD8717
Chemical/Pharm GKB GenePA36707
Clinical trialTRADD
Other databases
Probes
Litterature
PubMed114 Pubmed reference(s) in Entrez
CoreMineTRADD
iHOPTRADD
OncoSearchTRADD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 19:23:19 CEST 2014

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