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TRADD (TNFRSF1A associated via death domain)

Identity

Alias (NCBI)Hs.89862
HGNC (Hugo) TRADD
HGNC Alias symbHs.89862
HGNC Previous nameTNFRSF1A-associated via death domain
LocusID (NCBI) 8717
Atlas_Id 42685
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 67154186 and ends at 67159909 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TRADD (16q22.1) / B3GNT9 (16q22.1)TRADD (16q22.1) / SLC12A1 (15q21.1)TRADD 16q22.1 / SLC12A1 15q21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRADD   12030
Cards
Entrez_Gene (NCBI)TRADD    TNFRSF1A associated via death domain
AliasesHs.89862
GeneCards (Weizmann)TRADD
Ensembl hg19 (Hinxton)ENSG00000102871 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102871 [Gene_View]  ENSG00000102871 [Sequence]  chr16:67154186-67159909 [Contig_View]  TRADD [Vega]
ICGC DataPortalENSG00000102871
TCGA cBioPortalTRADD
AceView (NCBI)TRADD
Genatlas (Paris)TRADD
SOURCE (Princeton)TRADD
Genetics Home Reference (NIH)TRADD
Genomic and cartography
GoldenPath hg38 (UCSC)TRADD  -     chr16:67154186-67159909 -  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRADD  -     16q22.1   [Description]    (hg19-Feb_2009)
GoldenPathTRADD - 16q22.1 [CytoView hg19]  TRADD - 16q22.1 [CytoView hg38]
ImmunoBaseENSG00000102871
Genome Data Viewer NCBITRADD [Mapview hg19]  
OMIM603500   
Gene and transcription
Genbank (Entrez)AK090673 AK301593 AK315654 BC004491 BG717460
RefSeq transcript (Entrez)NM_001323552 NM_003789 NM_153425
Consensus coding sequences : CCDS (NCBI)TRADD
Gene ExpressionTRADD [ NCBI-GEO ]   TRADD [ EBI - ARRAY_EXPRESS ]   TRADD [ SEEK ]   TRADD [ MEM ]
Gene Expression Viewer (FireBrowse)TRADD [ Firebrowse - Broad ]
GenevisibleExpression of TRADD in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8717
GTEX Portal (Tissue expression)TRADD
Human Protein AtlasENSG00000102871-TRADD [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15628   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15628  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15628
PhosPhoSitePlusQ15628
Domaine pattern : Prosite (Expaxy)DEATH_DOMAIN (PS50017)   
Domains : Interpro (EBI)DEATH-like_dom_sf    Death_domain    TRADD    TRADD_N    TRADD_N_sf   
Domain families : Pfam (Sanger)Death (PF00531)    TRADD_N (PF09034)   
Domain families : Pfam (NCBI)pfam00531    pfam09034   
Domain families : Smart (EMBL)DEATH (SM00005)  
Conserved Domain (NCBI)TRADD
PDB (RSDB)1F2H    1F3V    5XME    6AC0   
PDB Europe1F2H    1F3V    5XME    6AC0   
PDB (PDBSum)1F2H    1F3V    5XME    6AC0   
PDB (IMB)1F2H    1F3V    5XME    6AC0   
Structural Biology KnowledgeBase1F2H    1F3V    5XME    6AC0   
SCOP (Structural Classification of Proteins)1F2H    1F3V    5XME    6AC0   
CATH (Classification of proteins structures)1F2H    1F3V    5XME    6AC0   
SuperfamilyQ15628
AlphaFold pdb e-kbQ15628   
Human Protein Atlas [tissue]ENSG00000102871-TRADD [tissue]
HPRD04610
Protein Interaction databases
DIP (DOE-UCLA)Q15628
IntAct (EBI)Q15628
BioGRIDTRADD
STRING (EMBL)TRADD
ZODIACTRADD
Ontologies - Pathways
QuickGOQ15628
Ontology : AmiGOtumor necrosis factor receptor superfamily complex  tumor necrosis factor receptor superfamily complex  transmembrane receptor protein tyrosine kinase adaptor activity  transmembrane receptor protein tyrosine kinase adaptor activity  tumor necrosis factor receptor binding  protein binding  nucleus  cytoplasm  cytosol  cytoskeleton  plasma membrane  apoptotic process  activation of cysteine-type endopeptidase activity involved in apoptotic process  signal transduction  transmembrane receptor protein tyrosine kinase signaling pathway  I-kappaB kinase/NF-kappaB signaling  extrinsic apoptotic signaling pathway via death domain receptors  regulation of tumor necrosis factor-mediated signaling pathway  kinase binding  positive regulation of cell migration  death-inducing signaling complex  tumor necrosis factor-mediated signaling pathway  identical protein binding  positive regulation of apoptotic process  positive regulation of I-kappaB kinase/NF-kappaB signaling  receptor complex  protein-containing complex binding  membrane raft  positive regulation of inflammatory response  positive regulation of NF-kappaB transcription factor activity  positive regulation of NF-kappaB transcription factor activity  positive regulation of hair follicle development  death domain binding  cellular response to tumor necrosis factor  death-inducing signaling complex assembly  extrinsic apoptotic signaling pathway  extrinsic apoptotic signaling pathway  extrinsic apoptotic signaling pathway  positive regulation of NIK/NF-kappaB signaling  regulation of extrinsic apoptotic signaling pathway via death domain receptors  negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  
Ontology : EGO-EBItumor necrosis factor receptor superfamily complex  tumor necrosis factor receptor superfamily complex  transmembrane receptor protein tyrosine kinase adaptor activity  transmembrane receptor protein tyrosine kinase adaptor activity  tumor necrosis factor receptor binding  protein binding  nucleus  cytoplasm  cytosol  cytoskeleton  plasma membrane  apoptotic process  activation of cysteine-type endopeptidase activity involved in apoptotic process  signal transduction  transmembrane receptor protein tyrosine kinase signaling pathway  I-kappaB kinase/NF-kappaB signaling  extrinsic apoptotic signaling pathway via death domain receptors  regulation of tumor necrosis factor-mediated signaling pathway  kinase binding  positive regulation of cell migration  death-inducing signaling complex  tumor necrosis factor-mediated signaling pathway  identical protein binding  positive regulation of apoptotic process  positive regulation of I-kappaB kinase/NF-kappaB signaling  receptor complex  protein-containing complex binding  membrane raft  positive regulation of inflammatory response  positive regulation of NF-kappaB transcription factor activity  positive regulation of NF-kappaB transcription factor activity  positive regulation of hair follicle development  death domain binding  cellular response to tumor necrosis factor  death-inducing signaling complex assembly  extrinsic apoptotic signaling pathway  extrinsic apoptotic signaling pathway  extrinsic apoptotic signaling pathway  positive regulation of NIK/NF-kappaB signaling  regulation of extrinsic apoptotic signaling pathway via death domain receptors  negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  
Pathways : BIOCARTAHIV-I Nef: negative effector of Fas and TNF [Genes]    Induction of apoptosis through DR3 and DR4/5 Death Receptors [Genes]    Ceramide Signaling Pathway [Genes]    TNFR1 Signaling Pathway [Genes]    MAPKinase Signaling Pathway [Genes]    NF-kB Signaling Pathway [Genes]    Acetylation and Deacetylation of RelA in The Nucleus [Genes]    p38 MAPK Signaling Pathway [Genes]    TNF/Stress Related Signaling [Genes]    SODD/TNFR1 Signaling Pathway [Genes]   
Pathways : KEGGNF-kappa B signaling pathway    Apoptosis    RIG-I-like receptor signaling pathway    TNF signaling pathway    Adipocytokine signaling pathway    Tuberculosis    Hepatitis C    Epstein-Barr virus infection    Viral carcinogenesis   
NDEx NetworkTRADD
Atlas of Cancer Signalling NetworkTRADD
Wikipedia pathwaysTRADD
Orthology - Evolution
OrthoDB8717
GeneTree (enSembl)ENSG00000102871
Phylogenetic Trees/Animal Genes : TreeFamTRADD
Homologs : HomoloGeneTRADD
Homology/Alignments : Family Browser (UCSC)TRADD
Gene fusions - Rearrangements
Fusion : MitelmanTRADD/SLC12A1 [16q22.1/15q21.1]  
Fusion : QuiverTRADD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRADD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRADD
dbVarTRADD
ClinVarTRADD
MonarchTRADD
1000_GenomesTRADD 
Exome Variant ServerTRADD
GNOMAD BrowserENSG00000102871
Varsome BrowserTRADD
ACMGTRADD variants
VarityQ15628
Genomic Variants (DGV)TRADD [DGVbeta]
DECIPHERTRADD [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRADD 
Mutations
ICGC Data PortalTRADD 
TCGA Data PortalTRADD 
Broad Tumor PortalTRADD
OASIS PortalTRADD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRADD  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRADD
Mutations and Diseases : HGMDTRADD
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRADD
DgiDB (Drug Gene Interaction Database)TRADD
DoCM (Curated mutations)TRADD
CIViC (Clinical Interpretations of Variants in Cancer)TRADD
Cancer3DTRADD
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603500   
Orphanet
DisGeNETTRADD
MedgenTRADD
Genetic Testing Registry TRADD
NextProtQ15628 [Medical]
GENETestsTRADD
Target ValidationTRADD
Huge Navigator TRADD [HugePedia]
ClinGenTRADD
Clinical trials, drugs, therapy
MyCancerGenomeTRADD
Protein Interactions : CTDTRADD
Pharm GKB GenePA36707
PharosQ15628
Clinical trialTRADD
Miscellaneous
canSAR (ICR)TRADD
HarmonizomeTRADD
DataMed IndexTRADD
Probes
Litterature
PubMed158 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRADD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:36:08 CEST 2021

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