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TRAF7 (TNF receptor associated factor 7)

Identity

Other namesRFWD1
RNF119
HGNC (Hugo) TRAF7
LocusID (NCBI) 84231
Atlas_Id 42094
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 2205799 and ends at 2228130 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TRAF7 (16p13.3) / EIF4A1 (17p13.1)TRAF7 (16p13.3) / WDR24 (16p13.3)TRAF7 16p13.3 / WDR24 16p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRAF7   20456
Cards
Entrez_Gene (NCBI)TRAF7  84231  TNF receptor associated factor 7
AliasesRFWD1; RNF119
GeneCards (Weizmann)TRAF7
Ensembl hg19 (Hinxton)ENSG00000131653 [Gene_View]  chr16:2205799-2228130 [Contig_View]  TRAF7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000131653 [Gene_View]  chr16:2205799-2228130 [Contig_View]  TRAF7 [Vega]
ICGC DataPortalENSG00000131653
TCGA cBioPortalTRAF7
AceView (NCBI)TRAF7
Genatlas (Paris)TRAF7
WikiGenes84231
SOURCE (Princeton)TRAF7
Genomic and cartography
GoldenPath hg19 (UCSC)TRAF7  -     chr16:2205799-2228130 +  16p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TRAF7  -     16p13.3   [Description]    (hg38-Dec_2013)
EnsemblTRAF7 - 16p13.3 [CytoView hg19]  TRAF7 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBITRAF7 [Mapview hg19]  TRAF7 [Mapview hg38]
OMIM606692   
Gene and transcription
Genbank (Entrez)AK090624 AL136921 AW245178 AY569455 BC024267
RefSeq transcript (Entrez)NM_032271 NM_206835
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010393 NW_004929400
Consensus coding sequences : CCDS (NCBI)TRAF7
Cluster EST : UnigeneHs.713632 [ NCBI ]
CGAP (NCI)Hs.713632
Alternative Splicing GalleryENSG00000131653
Gene ExpressionTRAF7 [ NCBI-GEO ]   TRAF7 [ EBI - ARRAY_EXPRESS ]   TRAF7 [ SEEK ]   TRAF7 [ MEM ]
Gene Expression Viewer (FireBrowse)TRAF7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84231
GTEX Portal (Tissue expression)TRAF7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6Q0C0 (Uniprot)
NextProtQ6Q0C0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6Q0C0
Splice isoforms : SwissVarQ6Q0C0 (Swissvar)
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ6Q0C0
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)    ZF_TRAF (PS50145)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    SIAH-type    TRAF-like    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom    Znf_C3HC4_RING-type    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS    Znf_TRAF   
Domain families : Pfam (Sanger)WD40 (PF00400)    zf-C3HC4 (PF00097)   
Domain families : Pfam (NCBI)pfam00400    pfam00097   
Domain families : Smart (EMBL)RING (SM00184)  WD40 (SM00320)  
DMDM Disease mutations84231
Blocks (Seattle)TRAF7
SuperfamilyQ6Q0C0
Human Protein AtlasENSG00000131653
Peptide AtlasQ6Q0C0
HPRD06977
IPIIPI00395631   IPI00470778   
Protein Interaction databases
DIP (DOE-UCLA)Q6Q0C0
IntAct (EBI)Q6Q0C0
FunCoupENSG00000131653
BioGRIDTRAF7
STRING (EMBL)TRAF7
ZODIACTRAF7
Ontologies - Pathways
QuickGOQ6Q0C0
Ontology : AmiGOubiquitin ligase complex  activation of MAPKKK activity  ubiquitin-protein transferase activity  protein binding  plasma membrane  transcription, DNA-templated  regulation of transcription, DNA-templated  apoptotic process  zinc ion binding  cytoplasmic, membrane-bounded vesicle  protein ubiquitination  protein ubiquitination  ligase activity  intracellular membrane-bounded organelle  positive regulation of MAPK cascade  positive regulation of apoptotic signaling pathway  
Ontology : EGO-EBIubiquitin ligase complex  activation of MAPKKK activity  ubiquitin-protein transferase activity  protein binding  plasma membrane  transcription, DNA-templated  regulation of transcription, DNA-templated  apoptotic process  zinc ion binding  cytoplasmic, membrane-bounded vesicle  protein ubiquitination  protein ubiquitination  ligase activity  intracellular membrane-bounded organelle  positive regulation of MAPK cascade  positive regulation of apoptotic signaling pathway  
NDEx Network
Atlas of Cancer Signalling NetworkTRAF7
Wikipedia pathwaysTRAF7
Orthology - Evolution
OrthoDB84231
GeneTree (enSembl)ENSG00000131653
Phylogenetic Trees/Animal Genes : TreeFamTRAF7
Homologs : HomoloGeneTRAF7
Homology/Alignments : Family Browser (UCSC)TRAF7
Gene fusions - Rearrangements
Fusion: TCGATRAF7 16p13.3 WDR24 16p13.3 LAML
Polymorphisms : SNP, variants
NCBI Variation ViewerTRAF7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRAF7
dbVarTRAF7
ClinVarTRAF7
1000_GenomesTRAF7 
Exome Variant ServerTRAF7
ExAC (Exome Aggregation Consortium)TRAF7 (select the gene name)
Genetic variants : HAPMAP84231
Genomic Variants (DGV)TRAF7 [DGVbeta]
Mutations
ICGC Data PortalTRAF7 
TCGA Data PortalTRAF7 
Broad Tumor PortalTRAF7
OASIS PortalTRAF7 [ Somatic mutations - Copy number]
Cancer Gene: CensusTRAF7 
Somatic Mutations in Cancer : COSMICTRAF7 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRAF7
DgiDB (Drug Gene Interaction Database)TRAF7
DoCM (Curated mutations)TRAF7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRAF7 (select a term)
intoGenTRAF7
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:2205799-2228130  ENSG00000131653
CONAN: Copy Number AnalysisTRAF7 
Mutations and Diseases : HGMDTRAF7
OMIM606692   
MedgenTRAF7
Genetic Testing Registry TRAF7
NextProtQ6Q0C0 [Medical]
TSGene84231
GENETestsTRAF7
Huge Navigator TRAF7 [HugePedia]
snp3D : Map Gene to Disease84231
BioCentury BCIQTRAF7
ClinGenTRAF7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84231
Chemical/Pharm GKB GenePA134917323
Clinical trialTRAF7
Miscellaneous
canSAR (ICR)TRAF7 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRAF7
EVEXTRAF7
GoPubMedTRAF7
iHOPTRAF7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 19:28:46 CEST 2016

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