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TRAM1 (translocation associated membrane protein 1)

Identity

Alias (NCBI)PNAS8
TRAM
TRAMP
HGNC (Hugo) TRAM1
HGNC Alias symbTRAM
TRAMP
LocusID (NCBI) 23471
Atlas_Id 42689
Location 8q13.3  [Link to chromosome band 8q13]
Location_base_pair Starts at 70573218 and ends at 70608416 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AD_1 () / TRAM1 (8q13.3)AUTS2 (7q11.22) / TRAM1 (8q13.3)TRAM1 (8q13.3) / CLVS1 (8q12.3)
TRAM1 (8q13.3) / RAP1A (1p13.2)TRAM1 (8q13.3) / ZFPM2 (8q23.1)TRAM1 8q13.3 / CLVS1 8q12.3
TRAM1 8q13.3 / ZFPM2 8q23.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRAM1   20568
Cards
Entrez_Gene (NCBI)TRAM1    translocation associated membrane protein 1
AliasesPNAS8; TRAM; TRAMP
GeneCards (Weizmann)TRAM1
Ensembl hg19 (Hinxton)ENSG00000067167 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000067167 [Gene_View]  ENSG00000067167 [Sequence]  chr8:70573218-70608416 [Contig_View]  TRAM1 [Vega]
ICGC DataPortalENSG00000067167
TCGA cBioPortalTRAM1
AceView (NCBI)TRAM1
Genatlas (Paris)TRAM1
SOURCE (Princeton)TRAM1
Genetics Home Reference (NIH)TRAM1
Genomic and cartography
GoldenPath hg38 (UCSC)TRAM1  -     chr8:70573218-70608416 -  8q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRAM1  -     8q13.3   [Description]    (hg19-Feb_2009)
GoldenPathTRAM1 - 8q13.3 [CytoView hg19]  TRAM1 - 8q13.3 [CytoView hg38]
ImmunoBaseENSG00000067167
Genome Data Viewer NCBITRAM1 [Mapview hg19]  
OMIM605190   
Gene and transcription
Genbank (Entrez)AA740941 AF130055 AF274933 AK289397 AK292777
RefSeq transcript (Entrez)NM_001317804 NM_001317805 NM_014294
Consensus coding sequences : CCDS (NCBI)TRAM1
Gene ExpressionTRAM1 [ NCBI-GEO ]   TRAM1 [ EBI - ARRAY_EXPRESS ]   TRAM1 [ SEEK ]   TRAM1 [ MEM ]
Gene Expression Viewer (FireBrowse)TRAM1 [ Firebrowse - Broad ]
GenevisibleExpression of TRAM1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23471
GTEX Portal (Tissue expression)TRAM1
Human Protein AtlasENSG00000067167-TRAM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15629   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15629  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15629
PhosPhoSitePlusQ15629
Domaine pattern : Prosite (Expaxy)TLC (PS50922)   
Domains : Interpro (EBI)TLC-dom    TRAM1    Translocation_assoc_membrane   
Domain families : Pfam (Sanger)TRAM1 (PF08390)    TRAM_LAG1_CLN8 (PF03798)   
Domain families : Pfam (NCBI)pfam08390    pfam03798   
Domain families : Smart (EMBL)TLC (SM00724)  
Conserved Domain (NCBI)TRAM1
SuperfamilyQ15629
AlphaFold pdb e-kbQ15629   
Human Protein Atlas [tissue]ENSG00000067167-TRAM1 [tissue]
HPRD05545
Protein Interaction databases
DIP (DOE-UCLA)Q15629
IntAct (EBI)Q15629
BioGRIDTRAM1
STRING (EMBL)TRAM1
ZODIACTRAM1
Ontologies - Pathways
QuickGOQ15629
Ontology : AmiGOprotein binding  endoplasmic reticulum  cotranslational protein targeting to membrane  SRP-dependent cotranslational protein targeting to membrane, translocation  integral component of membrane  integral component of endoplasmic reticulum membrane  integral component of endoplasmic reticulum membrane  integral component of endoplasmic reticulum membrane  signaling receptor activity  protein insertion into ER membrane  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum  cotranslational protein targeting to membrane  SRP-dependent cotranslational protein targeting to membrane, translocation  integral component of membrane  integral component of endoplasmic reticulum membrane  integral component of endoplasmic reticulum membrane  integral component of endoplasmic reticulum membrane  signaling receptor activity  protein insertion into ER membrane  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkTRAM1
Atlas of Cancer Signalling NetworkTRAM1
Wikipedia pathwaysTRAM1
Orthology - Evolution
OrthoDB23471
GeneTree (enSembl)ENSG00000067167
Phylogenetic Trees/Animal Genes : TreeFamTRAM1
Homologs : HomoloGeneTRAM1
Homology/Alignments : Family Browser (UCSC)TRAM1
Gene fusions - Rearrangements
Fusion : MitelmanTRAM1/CLVS1 [8q13.3/8q12.3]  
Fusion : MitelmanTRAM1/ZFPM2 [8q13.3/8q23.1]  
Fusion Cancer (Beijing)AD_1 [TRAM1]  -  8q13.3 [FUSC002808]
Fusion : QuiverTRAM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRAM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRAM1
dbVarTRAM1
ClinVarTRAM1
MonarchTRAM1
1000_GenomesTRAM1 
Exome Variant ServerTRAM1
GNOMAD BrowserENSG00000067167
Varsome BrowserTRAM1
ACMGTRAM1 variants
VarityQ15629
Genomic Variants (DGV)TRAM1 [DGVbeta]
DECIPHERTRAM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRAM1 
Mutations
ICGC Data PortalTRAM1 
TCGA Data PortalTRAM1 
Broad Tumor PortalTRAM1
OASIS PortalTRAM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRAM1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRAM1
Mutations and Diseases : HGMDTRAM1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRAM1
DgiDB (Drug Gene Interaction Database)TRAM1
DoCM (Curated mutations)TRAM1
CIViC (Clinical Interpretations of Variants in Cancer)TRAM1
Cancer3DTRAM1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605190   
Orphanet
DisGeNETTRAM1
MedgenTRAM1
Genetic Testing Registry TRAM1
NextProtQ15629 [Medical]
GENETestsTRAM1
Target ValidationTRAM1
Huge Navigator TRAM1 [HugePedia]
ClinGenTRAM1
Clinical trials, drugs, therapy
MyCancerGenomeTRAM1
Protein Interactions : CTDTRAM1
Pharm GKB GenePA134955644
PharosQ15629
Clinical trialTRAM1
Miscellaneous
canSAR (ICR)TRAM1
HarmonizomeTRAM1
DataMed IndexTRAM1
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRAM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:10 CEST 2021

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