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TRAM2 (translocation associated membrane protein 2)

Identity

Alias_symbol (synonym)KIAA0057
Other alias-
HGNC (Hugo) TRAM2
LocusID (NCBI) 9697
Atlas_Id 42691
Location 6p12.2  [Link to chromosome band 6p12]
Location_base_pair Starts at 52497402 and ends at 52577064 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DLGAP1 (18p11.31) / TRAM2 (6p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRAM2   16855
Cards
Entrez_Gene (NCBI)TRAM2  9697  translocation associated membrane protein 2
Aliases
GeneCards (Weizmann)TRAM2
Ensembl hg19 (Hinxton)ENSG00000065308 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000065308 [Gene_View]  ENSG00000065308 [Sequence]  chr6:52497402-52577064 [Contig_View]  TRAM2 [Vega]
ICGC DataPortalENSG00000065308
TCGA cBioPortalTRAM2
AceView (NCBI)TRAM2
Genatlas (Paris)TRAM2
WikiGenes9697
SOURCE (Princeton)TRAM2
Genetics Home Reference (NIH)TRAM2
Genomic and cartography
GoldenPath hg38 (UCSC)TRAM2  -     chr6:52497402-52577064 -  6p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRAM2  -     6p12.2   [Description]    (hg19-Feb_2009)
EnsemblTRAM2 - 6p12.2 [CytoView hg19]  TRAM2 - 6p12.2 [CytoView hg38]
Mapping of homologs : NCBITRAM2 [Mapview hg19]  TRAM2 [Mapview hg38]
OMIM608485   
Gene and transcription
Genbank (Entrez)AA044636 AB621814 AK291751 AK311560 AU140711
RefSeq transcript (Entrez)NM_012288
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRAM2
Cluster EST : UnigeneHs.520182 [ NCBI ]
CGAP (NCI)Hs.520182
Alternative Splicing GalleryENSG00000065308
Gene ExpressionTRAM2 [ NCBI-GEO ]   TRAM2 [ EBI - ARRAY_EXPRESS ]   TRAM2 [ SEEK ]   TRAM2 [ MEM ]
Gene Expression Viewer (FireBrowse)TRAM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9697
GTEX Portal (Tissue expression)TRAM2
Human Protein AtlasENSG00000065308-TRAM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15035   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15035  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15035
Splice isoforms : SwissVarQ15035
PhosPhoSitePlusQ15035
Domaine pattern : Prosite (Expaxy)TLC (PS50922)   
Domains : Interpro (EBI)TLC-dom    TRAM1    Translocation_assoc_membrane   
Domain families : Pfam (Sanger)TRAM1 (PF08390)    TRAM_LAG1_CLN8 (PF03798)   
Domain families : Pfam (NCBI)pfam08390    pfam03798   
Domain families : Smart (EMBL)TLC (SM00724)  
Conserved Domain (NCBI)TRAM2
DMDM Disease mutations9697
Blocks (Seattle)TRAM2
SuperfamilyQ15035
Human Protein Atlas [tissue]ENSG00000065308-TRAM2 [tissue]
Peptide AtlasQ15035
HPRD16338
IPIIPI00014218   
Protein Interaction databases
DIP (DOE-UCLA)Q15035
IntAct (EBI)Q15035
FunCoupENSG00000065308
BioGRIDTRAM2
STRING (EMBL)TRAM2
ZODIACTRAM2
Ontologies - Pathways
QuickGOQ15035
Ontology : AmiGOprotein binding  rough endoplasmic reticulum  SRP-dependent cotranslational protein targeting to membrane, translocation  integral component of membrane  collagen biosynthetic process  protein insertion into ER membrane  
Ontology : EGO-EBIprotein binding  rough endoplasmic reticulum  SRP-dependent cotranslational protein targeting to membrane, translocation  integral component of membrane  collagen biosynthetic process  protein insertion into ER membrane  
NDEx NetworkTRAM2
Atlas of Cancer Signalling NetworkTRAM2
Wikipedia pathwaysTRAM2
Orthology - Evolution
OrthoDB9697
GeneTree (enSembl)ENSG00000065308
Phylogenetic Trees/Animal Genes : TreeFamTRAM2
HOVERGENQ15035
HOGENOMQ15035
Homologs : HomoloGeneTRAM2
Homology/Alignments : Family Browser (UCSC)TRAM2
Gene fusions - Rearrangements
Fusion : QuiverTRAM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRAM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRAM2
dbVarTRAM2
ClinVarTRAM2
1000_GenomesTRAM2 
Exome Variant ServerTRAM2
ExAC (Exome Aggregation Consortium)ENSG00000065308
GNOMAD BrowserENSG00000065308
Varsome BrowserTRAM2
Genetic variants : HAPMAP9697
Genomic Variants (DGV)TRAM2 [DGVbeta]
DECIPHERTRAM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRAM2 
Mutations
ICGC Data PortalTRAM2 
TCGA Data PortalTRAM2 
Broad Tumor PortalTRAM2
OASIS PortalTRAM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRAM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRAM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRAM2
DgiDB (Drug Gene Interaction Database)TRAM2
DoCM (Curated mutations)TRAM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRAM2 (select a term)
intoGenTRAM2
Cancer3DTRAM2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608485   
Orphanet
DisGeNETTRAM2
MedgenTRAM2
Genetic Testing Registry TRAM2
NextProtQ15035 [Medical]
TSGene9697
GENETestsTRAM2
Target ValidationTRAM2
Huge Navigator TRAM2 [HugePedia]
snp3D : Map Gene to Disease9697
BioCentury BCIQTRAM2
ClinGenTRAM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9697
Chemical/Pharm GKB GenePA128394555
Clinical trialTRAM2
Miscellaneous
canSAR (ICR)TRAM2 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRAM2
EVEXTRAM2
GoPubMedTRAM2
iHOPTRAM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:46:35 CET 2018

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