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TRAPPC10 (trafficking protein particle complex 10)

Identity

Alias (NCBI)EHOC-1
EHOC1
GT334
TMEM1
TRS130
TRS30
HGNC (Hugo) TRAPPC10
HGNC Alias symbEHOC-1
TRS130
HGNC Alias nametrafficking protein particle complex subunit 130
 TRAPP 130 kDa subunit
HGNC Previous nameTMEM1
HGNC Previous nametransmembrane protein 1
LocusID (NCBI) 7109
Atlas_Id 54721
Location 21q22.3  [Link to chromosome band 21q22]
Location_base_pair Starts at 44012309 and ends at 44106551 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CABIN1 (22q11.23) / TRAPPC10 (21q22.3)PRELID3B (20q13.32) / TRAPPC10 (21q22.3)RRP1B (21q22.3) / TRAPPC10 (21q22.3)
TRAPPC10 (21q22.3) / BRWD1 (21q22.2)TRAPPC10 (21q22.3) / GCNT2 (6p24.3)TRAPPC10 (21q22.3) / GRID1 (10q23.1)
TRAPPC10 (21q22.3) / GRIK1 (21q21.3)TRAPPC10 (21q22.3) / TRAPPC10 (21q22.3)TRAPPC10 (21q22.3) / UBASH3A (21q22.3)
USP25 (21q21.1) / TRAPPC10 (21q22.3)SLMO2 TRAPPC10 21q22.3TRAPPC10 21q22.3 / BRWD1 21q22.2
TRAPPC10 21q22.3 / GRID1 10q23.1TRAPPC10 21q22.3 / GRIK1 21q21.3TRAPPC10 21q22.3 / UBASH3A 21q22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(21;21)(q21;q22) USP25/TRAPPC10
t(21;22)(q22;q11) CABIN1/TRAPPC10

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ]
  t(10;21)(q23;q22) TRAPPC10/GRID1
t(21;21)(q21;q22) TRAPPC10/GRIK1
TRAPPC10/BRWD1 (21q22)
TRAPPC10/UBASH3A (21q22)

External links

Nomenclature
HGNC (Hugo)TRAPPC10   11868
Cards
Entrez_Gene (NCBI)TRAPPC10    trafficking protein particle complex 10
AliasesEHOC-1; EHOC1; GT334; TMEM1; 
TRS130; TRS30
GeneCards (Weizmann)TRAPPC10
Ensembl hg19 (Hinxton)ENSG00000160218 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160218 [Gene_View]  ENSG00000160218 [Sequence]  chr21:44012309-44106551 [Contig_View]  TRAPPC10 [Vega]
ICGC DataPortalENSG00000160218
TCGA cBioPortalTRAPPC10
AceView (NCBI)TRAPPC10
Genatlas (Paris)TRAPPC10
SOURCE (Princeton)TRAPPC10
Genetics Home Reference (NIH)TRAPPC10
Genomic and cartography
GoldenPath hg38 (UCSC)TRAPPC10  -     chr21:44012309-44106551 +  21q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRAPPC10  -     21q22.3   [Description]    (hg19-Feb_2009)
GoldenPathTRAPPC10 - 21q22.3 [CytoView hg19]  TRAPPC10 - 21q22.3 [CytoView hg38]
ImmunoBaseENSG00000160218
genome Data Viewer NCBITRAPPC10 [Mapview hg19]  
OMIM602103   
Gene and transcription
Genbank (Entrez)AK095010 AK295369 AK300912 AK303570 AL559301
RefSeq transcript (Entrez)NM_001001723 NM_001351709 NM_003274
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRAPPC10
Alternative Splicing GalleryENSG00000160218
Gene ExpressionTRAPPC10 [ NCBI-GEO ]   TRAPPC10 [ EBI - ARRAY_EXPRESS ]   TRAPPC10 [ SEEK ]   TRAPPC10 [ MEM ]
Gene Expression Viewer (FireBrowse)TRAPPC10 [ Firebrowse - Broad ]
GenevisibleExpression of TRAPPC10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7109
GTEX Portal (Tissue expression)TRAPPC10
Human Protein AtlasENSG00000160218-TRAPPC10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48553   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48553  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48553
Splice isoforms : SwissVarP48553
PhosPhoSitePlusP48553
Domains : Interpro (EBI)TRAPP_II_complex_TRAPPC10   
Domain families : Pfam (Sanger)TRAPPC10 (PF12584)   
Domain families : Pfam (NCBI)pfam12584   
Conserved Domain (NCBI)TRAPPC10
Blocks (Seattle)TRAPPC10
SuperfamilyP48553
Human Protein Atlas [tissue]ENSG00000160218-TRAPPC10 [tissue]
Peptide AtlasP48553
HPRD03656
IPIIPI00298870   IPI01010016   IPI00552243   IPI00418693   IPI00917240   
Protein Interaction databases
DIP (DOE-UCLA)P48553
IntAct (EBI)P48553
BioGRIDTRAPPC10
STRING (EMBL)TRAPPC10
ZODIACTRAPPC10
Ontologies - Pathways
QuickGOP48553
Ontology : AmiGOGolgi membrane  protein binding  cytosol  intra-Golgi vesicle-mediated transport  TRAPP complex  early endosome to Golgi transport  COPII vesicle coating  TRAPPII protein complex  
Ontology : EGO-EBIGolgi membrane  protein binding  cytosol  intra-Golgi vesicle-mediated transport  TRAPP complex  early endosome to Golgi transport  COPII vesicle coating  TRAPPII protein complex  
NDEx NetworkTRAPPC10
Atlas of Cancer Signalling NetworkTRAPPC10
Wikipedia pathwaysTRAPPC10
Orthology - Evolution
OrthoDB7109
GeneTree (enSembl)ENSG00000160218
Phylogenetic Trees/Animal Genes : TreeFamTRAPPC10
HOGENOMP48553
Homologs : HomoloGeneTRAPPC10
Homology/Alignments : Family Browser (UCSC)TRAPPC10
Gene fusions - Rearrangements
Fusion : MitelmanSLMO2/21q22.3 [TRAPPC10/t(20;21)(q13;q22)]  
Fusion : MitelmanTRAPPC10/BRWD1 [21q22.3/21q22.2]  
Fusion : MitelmanTRAPPC10/GRID1 [21q22.3/10q23.1]  
Fusion : MitelmanTRAPPC10/GRIK1 [21q22.3/21q21.3]  
Fusion : MitelmanTRAPPC10/UBASH3A [21q22.3/21q22.3]  
Fusion : MitelmanUSP25/TRAPPC10 [21q21.1/21q22.3]  
Fusion PortalSLMO2 TRAPPC10 21q22.3 LUAD
Fusion PortalTRAPPC10 21q22.3 BRWD1 21q22.2 BRCA
Fusion PortalTRAPPC10 21q22.3 GRID1 10q23.1 OV
Fusion PortalTRAPPC10 21q22.3 GRIK1 21q21.3 LUAD
Fusion PortalTRAPPC10 21q22.3 UBASH3A 21q22.3 PRAD
Fusion : QuiverTRAPPC10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRAPPC10 [hg38]
dbVarTRAPPC10
ClinVarTRAPPC10
MonarchTRAPPC10
1000_GenomesTRAPPC10 
Exome Variant ServerTRAPPC10
GNOMAD BrowserENSG00000160218
Varsome BrowserTRAPPC10
Genomic Variants (DGV)TRAPPC10 [DGVbeta]
DECIPHERTRAPPC10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRAPPC10 
Mutations
ICGC Data PortalTRAPPC10 
TCGA Data PortalTRAPPC10 
Broad Tumor PortalTRAPPC10
OASIS PortalTRAPPC10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRAPPC10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRAPPC10
Mutations and Diseases : HGMDTRAPPC10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRAPPC10
DgiDB (Drug Gene Interaction Database)TRAPPC10
DoCM (Curated mutations)TRAPPC10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRAPPC10 (select a term)
intoGenTRAPPC10
Cancer3DTRAPPC10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602103   
Orphanet
DisGeNETTRAPPC10
MedgenTRAPPC10
Genetic Testing Registry TRAPPC10
NextProtP48553 [Medical]
GENETestsTRAPPC10
Target ValidationTRAPPC10
Huge Navigator TRAPPC10 [HugePedia]
ClinGenTRAPPC10 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeTRAPPC10
Protein Interactions : CTD
Pharm GKB GenePA162406870
PharosP48553
Clinical trialTRAPPC10
Miscellaneous
canSAR (ICR)TRAPPC10 (select the gene name)
HarmonizomeTRAPPC10
DataMed IndexTRAPPC10
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRAPPC10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jan 1 18:42:15 CET 2021
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