TRAPPC12 (trafficking protein particle complex subunit 12)

2014-11-01  

Identity

HGNC
LOCATION
2p25.3
LOCUSID
ALIAS
CGI-87,PEBAS,TTC-15,TTC15
FUSION GENES

Other Information

Locus ID:

NCBI: 51112
MIM: 614139
HGNC: 24284
Ensembl: ENSG00000171853

Variants:

dbSNP: 51112
ClinVar: 51112
TCGA: ENSG00000171853
COSMIC: TRAPPC12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171853ENST00000324266Q8WVT3
ENSG00000171853ENST00000382110Q8WVT3
ENSG00000171853ENST00000411973H7C2F7
ENSG00000171853ENST00000415624H7C0T3
ENSG00000171853ENST00000416918H7C0K3
ENSG00000171853ENST00000417243H7C1E5
ENSG00000171853ENST00000437733F8WCB4
ENSG00000171853ENST00000441099H7C185
ENSG00000171853ENST00000441983H7C373
ENSG00000171853ENST00000452495H0Y550
ENSG00000171853ENST00000457845H7C1M4

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
282402212017Mammalian TRAPPIII Complex positively modulates the recruitment of Sec13/31 onto COPII vesicles.9
287779342017Mutations in TRAPPC12 Manifest in Progressive Childhood Encephalopathy and Golgi Dysfunction.7

Citation

Dessen P

TRAPPC12 (trafficking protein particle complex subunit 12)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/75107/trappc12