Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TRARG1 (tumor suppressor candidate 5)

Identity

Alias_symbol (synonym)LOST1
IFITMD3
Other aliasBEC-1
DSPB1
HGNC (Hugo) TUSC5
LocusID (NCBI) 286753
Atlas_Id 42898
Location 17p13.3  [Link to chromosome band 17p13]
Location_base_pair Starts at 1279663 and ends at 1300987 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CAND1 12q14.3 / TUSC5 17p13.3
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(12;17)(q14;p13) CAND1/TUSC5


External links

Nomenclature
HGNC (Hugo)TUSC5   29592
Cards
Entrez_Gene (NCBI)TRARG1  286753  tumor suppressor candidate 5
AliasesBEC-1; DSPB1; IFITMD3; LOST1
GeneCards (Weizmann)TRARG1
Ensembl hg19 (Hinxton)ENSG00000184811 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184811 [Gene_View]  ENSG00000184811 [Sequence]  chr17:1279663-1300987 [Contig_View]  TRARG1 [Vega]
ICGC DataPortalENSG00000184811
TCGA cBioPortalTRARG1
AceView (NCBI)TRARG1
Genatlas (Paris)TRARG1
WikiGenes286753
SOURCE (Princeton)TRARG1
Genetics Home Reference (NIH)TRARG1
Genomic and cartography
GoldenPath hg38 (UCSC)TRARG1  -     chr17:1279663-1300987 +  17p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRARG1  -     17p13.3   [Description]    (hg19-Feb_2009)
EnsemblTRARG1 - 17p13.3 [CytoView hg19]  TRARG1 - 17p13.3 [CytoView hg38]
Mapping of homologs : NCBITRARG1 [Mapview hg19]  TRARG1 [Mapview hg38]
OMIM612211   
Gene and transcription
Genbank (Entrez)AB090231 AL831929 BC142615
RefSeq transcript (Entrez)NM_172367
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRARG1
Cluster EST : UnigeneHs.146059 [ NCBI ]
CGAP (NCI)Hs.146059
Alternative Splicing GalleryENSG00000184811
Gene ExpressionTRARG1 [ NCBI-GEO ]   TRARG1 [ EBI - ARRAY_EXPRESS ]   TRARG1 [ SEEK ]   TRARG1 [ MEM ]
Gene Expression Viewer (FireBrowse)TRARG1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)286753
GTEX Portal (Tissue expression)TRARG1
Human Protein AtlasENSG00000184811-TRARG1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IXB3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IXB3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IXB3
Splice isoforms : SwissVarQ8IXB3
PhosPhoSitePlusQ8IXB3
Domains : Interpro (EBI)CD225/Dispanin_fam   
Domain families : Pfam (Sanger)CD225 (PF04505)   
Domain families : Pfam (NCBI)pfam04505   
Conserved Domain (NCBI)TRARG1
DMDM Disease mutations286753
Blocks (Seattle)TRARG1
SuperfamilyQ8IXB3
Human Protein Atlas [tissue]ENSG00000184811-TRARG1 [tissue]
Peptide AtlasQ8IXB3
HPRD18248
IPIIPI00217491   
Protein Interaction databases
DIP (DOE-UCLA)Q8IXB3
IntAct (EBI)Q8IXB3
FunCoupENSG00000184811
BioGRIDTRARG1
STRING (EMBL)TRARG1
ZODIACTRARG1
Ontologies - Pathways
QuickGOQ8IXB3
Ontology : AmiGOplasma membrane  response to biotic stimulus  membrane  integral component of membrane  cytoplasmic vesicle membrane  glucose import in response to insulin stimulus  plasma membrane fusion  endosome to plasma membrane protein transport  
Ontology : EGO-EBIplasma membrane  response to biotic stimulus  membrane  integral component of membrane  cytoplasmic vesicle membrane  glucose import in response to insulin stimulus  plasma membrane fusion  endosome to plasma membrane protein transport  
NDEx NetworkTRARG1
Atlas of Cancer Signalling NetworkTRARG1
Wikipedia pathwaysTRARG1
Orthology - Evolution
OrthoDB286753
GeneTree (enSembl)ENSG00000184811
Phylogenetic Trees/Animal Genes : TreeFamTUSC5
HOVERGENQ8IXB3
HOGENOMQ8IXB3
Homologs : HomoloGeneTRARG1
Homology/Alignments : Family Browser (UCSC)TRARG1
Gene fusions - Rearrangements
Fusion : MitelmanCAND1/TUSC5 [12q14.3/17p13.3]  [t(12;17)(q14;p13)]  
Fusion PortalCAND1 12q14.3 TUSC5 17p13.3 BRCA
Fusion : QuiverTRARG1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRARG1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRARG1
dbVarTRARG1
ClinVarTRARG1
1000_GenomesTRARG1 
Exome Variant ServerTRARG1
ExAC (Exome Aggregation Consortium)ENSG00000184811
GNOMAD BrowserENSG00000184811
Genetic variants : HAPMAP286753
Genomic Variants (DGV)TRARG1 [DGVbeta]
DECIPHERTRARG1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRARG1 
Mutations
ICGC Data PortalTUSC5 
TCGA Data PortalTUSC5 
Broad Tumor PortalTUSC5
OASIS PortalTUSC5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRARG1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTUSC5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRARG1
DgiDB (Drug Gene Interaction Database)TRARG1
DoCM (Curated mutations)TRARG1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRARG1 (select a term)
intoGenTRARG1
Cancer3DTRARG1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612211   
Orphanet
DisGeNETTRARG1
MedgenTRARG1
Genetic Testing Registry TRARG1
NextProtQ8IXB3 [Medical]
TSGene286753
GENETestsTRARG1
Target ValidationTRARG1
Huge Navigator TUSC5 [HugePedia]
snp3D : Map Gene to Disease286753
BioCentury BCIQTRARG1
ClinGenTRARG1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD286753
Chemical/Pharm GKB GenePA134868023
Clinical trialTRARG1
Miscellaneous
canSAR (ICR)TRARG1 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRARG1
EVEXTRARG1
GoPubMedTRARG1
iHOPTRARG1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:55:57 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.