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TRAT1 (T-cell receptor associated transmembrane adaptor 1)

Identity

Alias_namesTCRIM
T cell receptor interacting molecule
Alias_symbol (synonym)HSPC062
TRIM
Other aliaspp29/30
HGNC (Hugo) TRAT1
LocusID (NCBI) 50852
Atlas_Id 53544
Location 3q13.13  [Link to chromosome band 3q13]
Location_base_pair Starts at 108822698 and ends at 108855005 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRAT1   30698
Cards
Entrez_Gene (NCBI)TRAT1  50852  T-cell receptor associated transmembrane adaptor 1
AliasesHSPC062; TCRIM; TRIM; pp29/30
GeneCards (Weizmann)TRAT1
Ensembl hg19 (Hinxton)ENSG00000163519 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163519 [Gene_View]  chr3:108822698-108855005 [Contig_View]  TRAT1 [Vega]
ICGC DataPortalENSG00000163519
TCGA cBioPortalTRAT1
AceView (NCBI)TRAT1
Genatlas (Paris)TRAT1
WikiGenes50852
SOURCE (Princeton)TRAT1
Genetics Home Reference (NIH)TRAT1
Genomic and cartography
GoldenPath hg38 (UCSC)TRAT1  -     chr3:108822698-108855005 +  3q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRAT1  -     3q13.13   [Description]    (hg19-Feb_2009)
EnsemblTRAT1 - 3q13.13 [CytoView hg19]  TRAT1 - 3q13.13 [CytoView hg38]
Mapping of homologs : NCBITRAT1 [Mapview hg19]  TRAT1 [Mapview hg38]
OMIM604962   
Gene and transcription
Genbank (Entrez)AF161547 AJ224878 AJ240085 AK291991 AV735609
RefSeq transcript (Entrez)NM_001317747 NM_016388
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TRAT1
Cluster EST : UnigeneHs.138701 [ NCBI ]
CGAP (NCI)Hs.138701
Alternative Splicing GalleryENSG00000163519
Gene ExpressionTRAT1 [ NCBI-GEO ]   TRAT1 [ EBI - ARRAY_EXPRESS ]   TRAT1 [ SEEK ]   TRAT1 [ MEM ]
Gene Expression Viewer (FireBrowse)TRAT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50852
GTEX Portal (Tissue expression)TRAT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PIZ9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PIZ9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PIZ9
Splice isoforms : SwissVarQ6PIZ9
PhosPhoSitePlusQ6PIZ9
Domains : Interpro (EBI)T-cell_rcpt-assoc_TM_adapter-1   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain structure : Prodom (Prabi Lyon)T-cell_rcpt-assoc_TM_adapter-1 (PD306446)   
Conserved Domain (NCBI)TRAT1
DMDM Disease mutations50852
Blocks (Seattle)TRAT1
SuperfamilyQ6PIZ9
Human Protein AtlasENSG00000163519
Peptide AtlasQ6PIZ9
HPRD05392
IPIIPI00008993   IPI00795721   
Protein Interaction databases
DIP (DOE-UCLA)Q6PIZ9
IntAct (EBI)Q6PIZ9
FunCoupENSG00000163519
BioGRIDTRAT1
STRING (EMBL)TRAT1
ZODIACTRAT1
Ontologies - Pathways
QuickGOQ6PIZ9
Ontology : AmiGOnegative regulation of receptor recycling  adaptive immune response  transmembrane receptor protein tyrosine kinase adaptor activity  intracellular  plasma membrane  plasma membrane  integral component of plasma membrane  cellular defense response  signal transduction  transmembrane receptor protein tyrosine kinase signaling pathway  regulation of phosphatidylinositol 3-kinase signaling  T cell receptor complex  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  phosphatidylinositol-mediated signaling  positive regulation of calcium-mediated signaling  T cell receptor signaling pathway  positive regulation of T cell receptor signaling pathway  negative regulation of transport  
Ontology : EGO-EBInegative regulation of receptor recycling  adaptive immune response  transmembrane receptor protein tyrosine kinase adaptor activity  intracellular  plasma membrane  plasma membrane  integral component of plasma membrane  cellular defense response  signal transduction  transmembrane receptor protein tyrosine kinase signaling pathway  regulation of phosphatidylinositol 3-kinase signaling  T cell receptor complex  phosphatidylinositol phosphorylation  phosphatidylinositol-4,5-bisphosphate 3-kinase activity  phosphatidylinositol-mediated signaling  positive regulation of calcium-mediated signaling  T cell receptor signaling pathway  positive regulation of T cell receptor signaling pathway  negative regulation of transport  
NDEx NetworkTRAT1
Atlas of Cancer Signalling NetworkTRAT1
Wikipedia pathwaysTRAT1
Orthology - Evolution
OrthoDB50852
GeneTree (enSembl)ENSG00000163519
Phylogenetic Trees/Animal Genes : TreeFamTRAT1
HOVERGENQ6PIZ9
HOGENOMQ6PIZ9
Homologs : HomoloGeneTRAT1
Homology/Alignments : Family Browser (UCSC)TRAT1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRAT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRAT1
dbVarTRAT1
ClinVarTRAT1
1000_GenomesTRAT1 
Exome Variant ServerTRAT1
ExAC (Exome Aggregation Consortium)TRAT1 (select the gene name)
Genetic variants : HAPMAP50852
Genomic Variants (DGV)TRAT1 [DGVbeta]
DECIPHERTRAT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRAT1 
Mutations
ICGC Data PortalTRAT1 
TCGA Data PortalTRAT1 
Broad Tumor PortalTRAT1
OASIS PortalTRAT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRAT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRAT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRAT1
DgiDB (Drug Gene Interaction Database)TRAT1
DoCM (Curated mutations)TRAT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRAT1 (select a term)
intoGenTRAT1
Cancer3DTRAT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604962   
Orphanet
MedgenTRAT1
Genetic Testing Registry TRAT1
NextProtQ6PIZ9 [Medical]
TSGene50852
GENETestsTRAT1
Huge Navigator TRAT1 [HugePedia]
snp3D : Map Gene to Disease50852
BioCentury BCIQTRAT1
ClinGenTRAT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD50852
Chemical/Pharm GKB GenePA128394655
Clinical trialTRAT1
Miscellaneous
canSAR (ICR)TRAT1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRAT1
EVEXTRAT1
GoPubMedTRAT1
iHOPTRAT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:42:06 CEST 2017

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