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TREH (trehalase)

Identity

Alias (NCBI)TRE
TREA
TREHD
HGNC (Hugo) TREH
HGNC Alias symbTRE
TREA
MGC129621
HGNC Alias namealpha,alpha-trehalase
 alpha,alpha-trehalose glucohydrolase
HGNC Previous nametrehalase (brush-border membrane glycoprotein)
LocusID (NCBI) 11181
Atlas_Id 54001
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 118657316 and ends at 118679650 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
WDR87 (19q13.13) / TREH (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TREH   12266
Cards
Entrez_Gene (NCBI)TREH    trehalase
AliasesTRE; TREA; TREHD
GeneCards (Weizmann)TREH
Ensembl hg19 (Hinxton)ENSG00000118094 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118094 [Gene_View]  ENSG00000118094 [Sequence]  chr11:118657316-118679650 [Contig_View]  TREH [Vega]
ICGC DataPortalENSG00000118094
TCGA cBioPortalTREH
AceView (NCBI)TREH
Genatlas (Paris)TREH
SOURCE (Princeton)TREH
Genetics Home Reference (NIH)TREH
Genomic and cartography
GoldenPath hg38 (UCSC)TREH  -     chr11:118657316-118679650 -  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TREH  -     11q23.3   [Description]    (hg19-Feb_2009)
GoldenPathTREH - 11q23.3 [CytoView hg19]  TREH - 11q23.3 [CytoView hg38]
ImmunoBaseENSG00000118094
Genome Data Viewer NCBITREH [Mapview hg19]  
OMIM275360   612119   
Gene and transcription
Genbank (Entrez)AB000824 AK091981 AK223140 AK223143 AK309565
RefSeq transcript (Entrez)NM_001301065 NM_007180
Consensus coding sequences : CCDS (NCBI)TREH
Gene ExpressionTREH [ NCBI-GEO ]   TREH [ EBI - ARRAY_EXPRESS ]   TREH [ SEEK ]   TREH [ MEM ]
Gene Expression Viewer (FireBrowse)TREH [ Firebrowse - Broad ]
GenevisibleExpression of TREH in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11181
GTEX Portal (Tissue expression)TREH
Human Protein AtlasENSG00000118094-TREH [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43280   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43280  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43280
PhosPhoSitePlusO43280
Domaine pattern : Prosite (Expaxy)TREHALASE_1 (PS00927)    TREHALASE_2 (PS00928)   
Domains : Interpro (EBI)6-hairpin_glycosidase_sf    6hp_glycosidase-like_sf    Glyco_hydro_37    Glyco_hydro_37_CS   
Domain families : Pfam (Sanger)Trehalase (PF01204)   
Domain families : Pfam (NCBI)pfam01204   
Conserved Domain (NCBI)TREH
SuperfamilyO43280
AlphaFold pdb e-kbO43280   
Human Protein Atlas [tissue]ENSG00000118094-TREH [tissue]
HPRD02038
Protein Interaction databases
DIP (DOE-UCLA)O43280
IntAct (EBI)O43280
BioGRIDTREH
STRING (EMBL)TREH
ZODIACTREH
Ontologies - Pathways
QuickGOO43280
Ontology : AmiGOalpha,alpha-trehalase activity  trehalose metabolic process  trehalose catabolic process  animal organ morphogenesis  anchored component of membrane  anchored component of plasma membrane  extracellular exosome  
Ontology : EGO-EBIalpha,alpha-trehalase activity  trehalose metabolic process  trehalose catabolic process  animal organ morphogenesis  anchored component of membrane  anchored component of plasma membrane  extracellular exosome  
Pathways : KEGGStarch and sucrose metabolism   
NDEx NetworkTREH
Atlas of Cancer Signalling NetworkTREH
Wikipedia pathwaysTREH
Orthology - Evolution
OrthoDB11181
GeneTree (enSembl)ENSG00000118094
Phylogenetic Trees/Animal Genes : TreeFamTREH
Homologs : HomoloGeneTREH
Homology/Alignments : Family Browser (UCSC)TREH
Gene fusions - Rearrangements
Fusion Cancer (Beijing)WDR87 [19q13.13]  -  TREH [11q23.3]  [FUSC001606]
Fusion : QuiverTREH
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTREH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TREH
dbVarTREH
ClinVarTREH
MonarchTREH
1000_GenomesTREH 
Exome Variant ServerTREH
GNOMAD BrowserENSG00000118094
Varsome BrowserTREH
ACMGTREH variants
VarityO43280
Genomic Variants (DGV)TREH [DGVbeta]
DECIPHERTREH [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTREH 
Mutations
ICGC Data PortalTREH 
TCGA Data PortalTREH 
Broad Tumor PortalTREH
OASIS PortalTREH [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTREH  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTREH
Mutations and Diseases : HGMDTREH
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTREH
DgiDB (Drug Gene Interaction Database)TREH
DoCM (Curated mutations)TREH
CIViC (Clinical Interpretations of Variants in Cancer)TREH
Cancer3DTREH
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM275360    612119   
Orphanet14985   
DisGeNETTREH
MedgenTREH
Genetic Testing Registry TREH
NextProtO43280 [Medical]
GENETestsTREH
Target ValidationTREH
Huge Navigator TREH [HugePedia]
ClinGenTREH
Clinical trials, drugs, therapy
MyCancerGenomeTREH
Protein Interactions : CTDTREH
Pharm GKB GenePA36946
PharosO43280
Clinical trialTREH
Miscellaneous
canSAR (ICR)TREH
HarmonizomeTREH
DataMed IndexTREH
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTREH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:36:14 CEST 2021

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