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TREH (trehalase)

Identity

Alias_namestrehalase (brush-border membrane glycoprotein)
Alias_symbol (synonym)TRE
TREA
MGC129621
Other alias
HGNC (Hugo) TREH
LocusID (NCBI) 11181
Atlas_Id 54001
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 118658232 and ends at 118679672 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
WDR87 (19q13.13) / TREH (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TREH   12266
Cards
Entrez_Gene (NCBI)TREH  11181  trehalase
AliasesTRE; TREA
GeneCards (Weizmann)TREH
Ensembl hg19 (Hinxton)ENSG00000118094 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118094 [Gene_View]  chr11:118658232-118679672 [Contig_View]  TREH [Vega]
ICGC DataPortalENSG00000118094
TCGA cBioPortalTREH
AceView (NCBI)TREH
Genatlas (Paris)TREH
WikiGenes11181
SOURCE (Princeton)TREH
Genetics Home Reference (NIH)TREH
Genomic and cartography
GoldenPath hg38 (UCSC)TREH  -     chr11:118658232-118679672 -  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TREH  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblTREH - 11q23.3 [CytoView hg19]  TREH - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBITREH [Mapview hg19]  TREH [Mapview hg38]
OMIM275360   612119   
Gene and transcription
Genbank (Entrez)AB000824 AK091981 AK223140 AK223143 AK309565
RefSeq transcript (Entrez)NM_001301065 NM_007180
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TREH
Cluster EST : UnigeneHs.129712 [ NCBI ]
CGAP (NCI)Hs.129712
Alternative Splicing GalleryENSG00000118094
Gene ExpressionTREH [ NCBI-GEO ]   TREH [ EBI - ARRAY_EXPRESS ]   TREH [ SEEK ]   TREH [ MEM ]
Gene Expression Viewer (FireBrowse)TREH [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11181
GTEX Portal (Tissue expression)TREH
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43280   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43280  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43280
Splice isoforms : SwissVarO43280
Catalytic activity : Enzyme3.2.1.28 [ Enzyme-Expasy ]   3.2.1.283.2.1.28 [ IntEnz-EBI ]   3.2.1.28 [ BRENDA ]   3.2.1.28 [ KEGG ]   
PhosPhoSitePlusO43280
Domaine pattern : Prosite (Expaxy)TREHALASE_1 (PS00927)    TREHALASE_2 (PS00928)   
Domains : Interpro (EBI)6-hairpin_glycosidase-like    Glyco_hydro_37    Glyco_hydro_37_CS   
Domain families : Pfam (Sanger)Trehalase (PF01204)   
Domain families : Pfam (NCBI)pfam01204   
Conserved Domain (NCBI)TREH
DMDM Disease mutations11181
Blocks (Seattle)TREH
SuperfamilyO43280
Human Protein AtlasENSG00000118094
Peptide AtlasO43280
HPRD02038
IPIIPI00011650   IPI00656107   IPI00902905   IPI00921204   
Protein Interaction databases
DIP (DOE-UCLA)O43280
IntAct (EBI)O43280
FunCoupENSG00000118094
BioGRIDTREH
STRING (EMBL)TREH
ZODIACTREH
Ontologies - Pathways
QuickGOO43280
Ontology : AmiGOalpha,alpha-trehalase activity  plasma membrane  trehalose metabolic process  trehalose catabolic process  animal organ morphogenesis  anchored component of plasma membrane  extracellular exosome  
Ontology : EGO-EBIalpha,alpha-trehalase activity  plasma membrane  trehalose metabolic process  trehalose catabolic process  animal organ morphogenesis  anchored component of plasma membrane  extracellular exosome  
Pathways : KEGGStarch and sucrose metabolism   
NDEx NetworkTREH
Atlas of Cancer Signalling NetworkTREH
Wikipedia pathwaysTREH
Orthology - Evolution
OrthoDB11181
GeneTree (enSembl)ENSG00000118094
Phylogenetic Trees/Animal Genes : TreeFamTREH
HOVERGENO43280
HOGENOMO43280
Homologs : HomoloGeneTREH
Homology/Alignments : Family Browser (UCSC)TREH
Gene fusions - Rearrangements
Fusion Cancer (Beijing)WDR87 [19q13.13]  -  TREH [11q23.3]  [FUSC001606]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTREH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TREH
dbVarTREH
ClinVarTREH
1000_GenomesTREH 
Exome Variant ServerTREH
ExAC (Exome Aggregation Consortium)TREH (select the gene name)
Genetic variants : HAPMAP11181
Genomic Variants (DGV)TREH [DGVbeta]
DECIPHERTREH [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTREH 
Mutations
ICGC Data PortalTREH 
TCGA Data PortalTREH 
Broad Tumor PortalTREH
OASIS PortalTREH [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTREH  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTREH
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TREH
DgiDB (Drug Gene Interaction Database)TREH
DoCM (Curated mutations)TREH (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TREH (select a term)
intoGenTREH
Cancer3DTREH(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM275360    612119   
Orphanet14985   
MedgenTREH
Genetic Testing Registry TREH
NextProtO43280 [Medical]
TSGene11181
GENETestsTREH
Target ValidationTREH
Huge Navigator TREH [HugePedia]
snp3D : Map Gene to Disease11181
BioCentury BCIQTREH
ClinGenTREH
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11181
Chemical/Pharm GKB GenePA36946
Clinical trialTREH
Miscellaneous
canSAR (ICR)TREH (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTREH
EVEXTREH
GoPubMedTREH
iHOPTREH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:36:12 CEST 2017

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