TREH (trehalase)

2014-06-01  

Identity

HGNC
LOCATION
11q23.3
LOCUSID
ALIAS
TRE,TREA,TREHD
FUSION GENES

Other Information

Locus ID:

NCBI: 11181
MIM: 275360
HGNC: 12266
Ensembl: ENSG00000118094

Variants:

dbSNP: 11181
ClinVar: 11181
TCGA: ENSG00000118094
COSMIC: TREH

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118094ENST00000264029O43280
ENSG00000118094ENST00000397925O43280
ENSG00000118094ENST00000613915A0A087WTJ4

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Starch and sucrose metabolismKEGGko00500
Starch and sucrose metabolismKEGGhsa00500
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Digestion of dietary carbohydrateREACTOMER-HSA-189085

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
223697352012Polymorphisms of TREH, IL4R and CCDC26 genes associated with risk of glioma.23
277014242016Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.22
289811172017Trehalose ameliorates oxidative stress-mediated mitochondrial dysfunction and ER stress via selective autophagy stimulation and autophagic flux restoration in osteoarthritis development.20
191264022009Human trehalase is a stress responsive protein in Saccharomyces cerevisiae.7
234681752013Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes.7
261563972015Association between RTEL1, PHLDB1, and TREH Polymorphisms and Glioblastoma Risk: A Case-Control Study.4

Citation

Dessen P

TREH (trehalase)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/54001/treh