Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TREM1 (triggering receptor expressed on myeloid cells 1)

Identity

Alias_symbol (synonym)TREM-1
CD354
Other alias
HGNC (Hugo) TREM1
LocusID (NCBI) 54210
Atlas_Id 52855
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41273605 and ends at 41286745 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TREM1   17760
Cards
Entrez_Gene (NCBI)TREM1  54210  triggering receptor expressed on myeloid cells 1
AliasesCD354; TREM-1
GeneCards (Weizmann)TREM1
Ensembl hg19 (Hinxton)ENSG00000124731 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124731 [Gene_View]  ENSG00000124731 [Sequence]  chr6:41273605-41286745 [Contig_View]  TREM1 [Vega]
ICGC DataPortalENSG00000124731
TCGA cBioPortalTREM1
AceView (NCBI)TREM1
Genatlas (Paris)TREM1
WikiGenes54210
SOURCE (Princeton)TREM1
Genetics Home Reference (NIH)TREM1
Genomic and cartography
GoldenPath hg38 (UCSC)TREM1  -     chr6:41273605-41286745 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TREM1  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblTREM1 - 6p21.1 [CytoView hg19]  TREM1 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBITREM1 [Mapview hg19]  TREM1 [Mapview hg38]
OMIM605085   
Gene and transcription
Genbank (Entrez)AF196329 AF287008 AK130673 AK223264 AK292162
RefSeq transcript (Entrez)NM_001242589 NM_001242590 NM_018643
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TREM1
Cluster EST : UnigeneHs.435955 [ NCBI ]
CGAP (NCI)Hs.435955
Alternative Splicing GalleryENSG00000124731
Gene ExpressionTREM1 [ NCBI-GEO ]   TREM1 [ EBI - ARRAY_EXPRESS ]   TREM1 [ SEEK ]   TREM1 [ MEM ]
Gene Expression Viewer (FireBrowse)TREM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54210
GTEX Portal (Tissue expression)TREM1
Human Protein AtlasENSG00000124731-TREM1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP99   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP99  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP99
Splice isoforms : SwissVarQ9NP99
PhosPhoSitePlusQ9NP99
Domains : Interpro (EBI)Ig-like_dom_sf    Ig-like_fold    Ig_sub    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)TREM1
DMDM Disease mutations54210
Blocks (Seattle)TREM1
PDB (SRS)1Q8M    1SMO   
PDB (PDBSum)1Q8M    1SMO   
PDB (IMB)1Q8M    1SMO   
PDB (RSDB)1Q8M    1SMO   
Structural Biology KnowledgeBase1Q8M    1SMO   
SCOP (Structural Classification of Proteins)1Q8M    1SMO   
CATH (Classification of proteins structures)1Q8M    1SMO   
SuperfamilyQ9NP99
Human Protein Atlas [tissue]ENSG00000124731-TREM1 [tissue]
Peptide AtlasQ9NP99
HPRD05472
IPIIPI00427321   IPI00427322   
Protein Interaction databases
DIP (DOE-UCLA)Q9NP99
IntAct (EBI)Q9NP99
FunCoupENSG00000124731
BioGRIDTREM1
STRING (EMBL)TREM1
ZODIACTREM1
Ontologies - Pathways
QuickGOQ9NP99
Ontology : AmiGOacute inflammatory response  extracellular region  intracellular  plasma membrane  humoral immune response  integral component of membrane  intracellular signal transduction  signaling receptor activity  innate immune response  regulation of immune response  leukocyte migration  scaffold protein binding  
Ontology : EGO-EBIacute inflammatory response  extracellular region  intracellular  plasma membrane  humoral immune response  integral component of membrane  intracellular signal transduction  signaling receptor activity  innate immune response  regulation of immune response  leukocyte migration  scaffold protein binding  
NDEx NetworkTREM1
Atlas of Cancer Signalling NetworkTREM1
Wikipedia pathwaysTREM1
Orthology - Evolution
OrthoDB54210
GeneTree (enSembl)ENSG00000124731
Phylogenetic Trees/Animal Genes : TreeFamTREM1
HOVERGENQ9NP99
HOGENOMQ9NP99
Homologs : HomoloGeneTREM1
Homology/Alignments : Family Browser (UCSC)TREM1
Gene fusions - Rearrangements
Fusion : QuiverTREM1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTREM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TREM1
dbVarTREM1
ClinVarTREM1
1000_GenomesTREM1 
Exome Variant ServerTREM1
ExAC (Exome Aggregation Consortium)ENSG00000124731
GNOMAD BrowserENSG00000124731
Varsome BrowserTREM1
Genetic variants : HAPMAP54210
Genomic Variants (DGV)TREM1 [DGVbeta]
DECIPHERTREM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTREM1 
Mutations
ICGC Data PortalTREM1 
TCGA Data PortalTREM1 
Broad Tumor PortalTREM1
OASIS PortalTREM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTREM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTREM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TREM1
DgiDB (Drug Gene Interaction Database)TREM1
DoCM (Curated mutations)TREM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TREM1 (select a term)
intoGenTREM1
Cancer3DTREM1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605085   
Orphanet
DisGeNETTREM1
MedgenTREM1
Genetic Testing Registry TREM1
NextProtQ9NP99 [Medical]
TSGene54210
GENETestsTREM1
Target ValidationTREM1
Huge Navigator TREM1 [HugePedia]
snp3D : Map Gene to Disease54210
BioCentury BCIQTREM1
ClinGenTREM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54210
Chemical/Pharm GKB GenePA38467
Clinical trialTREM1
Miscellaneous
canSAR (ICR)TREM1 (select the gene name)
Probes
Litterature
PubMed165 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTREM1
EVEXTREM1
GoPubMedTREM1
iHOPTREM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:46:41 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.