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TREML1 (triggering receptor expressed on myeloid cells like 1)

Identity

Alias_namestriggering receptor expressed on myeloid cells-like 1
Alias_symbol (synonym)TLT1
dJ238O23.3
Other aliasGLTL1825
PRO3438
TLT-1
HGNC (Hugo) TREML1
LocusID (NCBI) 340205
Atlas_Id 75132
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41149261 and ends at 41154349 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TREML1   20434
Cards
Entrez_Gene (NCBI)TREML1  340205  triggering receptor expressed on myeloid cells like 1
AliasesGLTL1825; PRO3438; TLT-1; TLT1; 
dJ238O23.3
GeneCards (Weizmann)TREML1
Ensembl hg19 (Hinxton)ENSG00000161911 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000161911 [Gene_View]  ENSG00000161911 [Sequence]  chr6:41149261-41154349 [Contig_View]  TREML1 [Vega]
ICGC DataPortalENSG00000161911
TCGA cBioPortalTREML1
AceView (NCBI)TREML1
Genatlas (Paris)TREML1
WikiGenes340205
SOURCE (Princeton)TREML1
Genetics Home Reference (NIH)TREML1
Genomic and cartography
GoldenPath hg38 (UCSC)TREML1  -     chr6:41149261-41154349 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TREML1  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblTREML1 - 6p21.1 [CytoView hg19]  TREML1 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBITREML1 [Mapview hg19]  TREML1 [Mapview hg38]
OMIM609714   
Gene and transcription
Genbank (Entrez)AF508193 AF534822 AF534823 AY358357 BC100944
RefSeq transcript (Entrez)NM_001271807 NM_001271808 NM_178174
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TREML1
Cluster EST : UnigeneHs.117331 [ NCBI ]
CGAP (NCI)Hs.117331
Alternative Splicing GalleryENSG00000161911
Gene ExpressionTREML1 [ NCBI-GEO ]   TREML1 [ EBI - ARRAY_EXPRESS ]   TREML1 [ SEEK ]   TREML1 [ MEM ]
Gene Expression Viewer (FireBrowse)TREML1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)340205
GTEX Portal (Tissue expression)TREML1
Human Protein AtlasENSG00000161911-TREML1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86YW5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86YW5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86YW5
Splice isoforms : SwissVarQ86YW5
PhosPhoSitePlusQ86YW5
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TREML1
DMDM Disease mutations340205
Blocks (Seattle)TREML1
PDB (SRS)2FRG   
PDB (PDBSum)2FRG   
PDB (IMB)2FRG   
PDB (RSDB)2FRG   
Structural Biology KnowledgeBase2FRG   
SCOP (Structural Classification of Proteins)2FRG   
CATH (Classification of proteins structures)2FRG   
SuperfamilyQ86YW5
Human Protein Atlas [tissue]ENSG00000161911-TREML1 [tissue]
Peptide AtlasQ86YW5
HPRD11645
IPIIPI00410333   IPI00795384   IPI00643076   
Protein Interaction databases
DIP (DOE-UCLA)Q86YW5
IntAct (EBI)Q86YW5
FunCoupENSG00000161911
BioGRIDTREML1
STRING (EMBL)TREML1
ZODIACTREML1
Ontologies - Pathways
QuickGOQ86YW5
Ontology : AmiGOplasma membrane  cell surface  integral component of membrane  platelet activation  platelet alpha granule  innate immune response  regulation of immune response  
Ontology : EGO-EBIplasma membrane  cell surface  integral component of membrane  platelet activation  platelet alpha granule  innate immune response  regulation of immune response  
NDEx NetworkTREML1
Atlas of Cancer Signalling NetworkTREML1
Wikipedia pathwaysTREML1
Orthology - Evolution
OrthoDB340205
GeneTree (enSembl)ENSG00000161911
Phylogenetic Trees/Animal Genes : TreeFamTREML1
HOVERGENQ86YW5
HOGENOMQ86YW5
Homologs : HomoloGeneTREML1
Homology/Alignments : Family Browser (UCSC)TREML1
Gene fusions - Rearrangements
Fusion : QuiverTREML1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTREML1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TREML1
dbVarTREML1
ClinVarTREML1
1000_GenomesTREML1 
Exome Variant ServerTREML1
ExAC (Exome Aggregation Consortium)ENSG00000161911
GNOMAD BrowserENSG00000161911
Varsome BrowserTREML1
Genetic variants : HAPMAP340205
Genomic Variants (DGV)TREML1 [DGVbeta]
DECIPHERTREML1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTREML1 
Mutations
ICGC Data PortalTREML1 
TCGA Data PortalTREML1 
Broad Tumor PortalTREML1
OASIS PortalTREML1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTREML1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTREML1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TREML1
DgiDB (Drug Gene Interaction Database)TREML1
DoCM (Curated mutations)TREML1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TREML1 (select a term)
intoGenTREML1
Cancer3DTREML1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609714   
Orphanet
DisGeNETTREML1
MedgenTREML1
Genetic Testing Registry TREML1
NextProtQ86YW5 [Medical]
TSGene340205
GENETestsTREML1
Target ValidationTREML1
Huge Navigator TREML1 [HugePedia]
snp3D : Map Gene to Disease340205
BioCentury BCIQTREML1
ClinGenTREML1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD340205
Chemical/Pharm GKB GenePA134878709
Clinical trialTREML1
Miscellaneous
canSAR (ICR)TREML1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTREML1
EVEXTREML1
GoPubMedTREML1
iHOPTREML1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:36:30 CEST 2018

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