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TREML2 (triggering receptor expressed on myeloid cells like 2)

Identity

Alias (NCBI)C6orf76
TLT-2
TLT2
dJ238O23.1
HGNC (Hugo) TREML2
HGNC Alias symbFLJ13693
TLT2
dJ238O23.1
HGNC Alias nameTREM-like transcript 2
HGNC Previous nameC6orf76
HGNC Previous namechromosome 6 open reading frame 76
 triggering receptor expressed on myeloid cells-like 2
LocusID (NCBI) 79865
Atlas_Id 75133
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41189749 and ends at 41201149 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TREML2   21092
Cards
Entrez_Gene (NCBI)TREML2    triggering receptor expressed on myeloid cells like 2
AliasesC6orf76; TLT-2; TLT2; dJ238O23.1
GeneCards (Weizmann)TREML2
Ensembl hg19 (Hinxton)ENSG00000112195 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112195 [Gene_View]  ENSG00000112195 [Sequence]  chr6:41189749-41201149 [Contig_View]  TREML2 [Vega]
ICGC DataPortalENSG00000112195
TCGA cBioPortalTREML2
AceView (NCBI)TREML2
Genatlas (Paris)TREML2
SOURCE (Princeton)TREML2
Genetics Home Reference (NIH)TREML2
Genomic and cartography
GoldenPath hg38 (UCSC)TREML2  -     chr6:41189749-41201149 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TREML2  -     6p21.1   [Description]    (hg19-Feb_2009)
GoldenPathTREML2 - 6p21.1 [CytoView hg19]  TREML2 - 6p21.1 [CytoView hg38]
ImmunoBaseENSG00000112195
Genome Data Viewer NCBITREML2 [Mapview hg19]  
OMIM609715   
Gene and transcription
Genbank (Entrez)AF534824 AJ420509 AK023755 AY358171 BC125078
RefSeq transcript (Entrez)NM_024807
Consensus coding sequences : CCDS (NCBI)TREML2
Gene ExpressionTREML2 [ NCBI-GEO ]   TREML2 [ EBI - ARRAY_EXPRESS ]   TREML2 [ SEEK ]   TREML2 [ MEM ]
Gene Expression Viewer (FireBrowse)TREML2 [ Firebrowse - Broad ]
GenevisibleExpression of TREML2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79865
GTEX Portal (Tissue expression)TREML2
Human Protein AtlasENSG00000112195-TREML2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T2D2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T2D2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T2D2
PhosPhoSitePlusQ5T2D2
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TREML2
SuperfamilyQ5T2D2
AlphaFold pdb e-kbQ5T2D2   
Human Protein Atlas [tissue]ENSG00000112195-TREML2 [tissue]
HPRD11646
Protein Interaction databases
DIP (DOE-UCLA)Q5T2D2
IntAct (EBI)Q5T2D2
BioGRIDTREML2
STRING (EMBL)TREML2
ZODIACTREML2
Ontologies - Pathways
QuickGOQ5T2D2
Ontology : AmiGOprotein binding  plasma membrane  cell surface  cell surface  integral component of membrane  signaling receptor activity  signaling receptor activity  T cell activation  T cell activation  regulation of immune response  
Ontology : EGO-EBIprotein binding  plasma membrane  cell surface  cell surface  integral component of membrane  signaling receptor activity  signaling receptor activity  T cell activation  T cell activation  regulation of immune response  
NDEx NetworkTREML2
Atlas of Cancer Signalling NetworkTREML2
Wikipedia pathwaysTREML2
Orthology - Evolution
OrthoDB79865
GeneTree (enSembl)ENSG00000112195
Phylogenetic Trees/Animal Genes : TreeFamTREML2
Homologs : HomoloGeneTREML2
Homology/Alignments : Family Browser (UCSC)TREML2
Gene fusions - Rearrangements
Fusion : QuiverTREML2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTREML2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TREML2
dbVarTREML2
ClinVarTREML2
MonarchTREML2
1000_GenomesTREML2 
Exome Variant ServerTREML2
GNOMAD BrowserENSG00000112195
Varsome BrowserTREML2
ACMGTREML2 variants
VarityQ5T2D2
Genomic Variants (DGV)TREML2 [DGVbeta]
DECIPHERTREML2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTREML2 
Mutations
ICGC Data PortalTREML2 
TCGA Data PortalTREML2 
Broad Tumor PortalTREML2
OASIS PortalTREML2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTREML2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTREML2
Mutations and Diseases : HGMDTREML2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTREML2
DgiDB (Drug Gene Interaction Database)TREML2
DoCM (Curated mutations)TREML2
CIViC (Clinical Interpretations of Variants in Cancer)TREML2
Cancer3DTREML2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609715   
Orphanet
DisGeNETTREML2
MedgenTREML2
Genetic Testing Registry TREML2
NextProtQ5T2D2 [Medical]
GENETestsTREML2
Target ValidationTREML2
Huge Navigator TREML2 [HugePedia]
ClinGenTREML2
Clinical trials, drugs, therapy
MyCancerGenomeTREML2
Protein Interactions : CTDTREML2
Pharm GKB GenePA134921444
PharosQ5T2D2
Clinical trialTREML2
Miscellaneous
canSAR (ICR)TREML2
HarmonizomeTREML2
DataMed IndexTREML2
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTREML2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:26:50 CEST 2021

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