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TREML2 (triggering receptor expressed on myeloid cells like 2)

Identity

Alias_namesC6orf76
chromosome 6 open reading frame 76
triggering receptor expressed on myeloid cells-like 2
Alias_symbol (synonym)FLJ13693
TLT2
dJ238O23.1
Other aliasTLT-2
HGNC (Hugo) TREML2
LocusID (NCBI) 79865
Atlas_Id 75133
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41189749 and ends at 41201187 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TREML2   21092
Cards
Entrez_Gene (NCBI)TREML2  79865  triggering receptor expressed on myeloid cells like 2
AliasesC6orf76; TLT-2; TLT2; dJ238O23.1
GeneCards (Weizmann)TREML2
Ensembl hg19 (Hinxton)ENSG00000112195 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112195 [Gene_View]  ENSG00000112195 [Sequence]  chr6:41189749-41201187 [Contig_View]  TREML2 [Vega]
ICGC DataPortalENSG00000112195
TCGA cBioPortalTREML2
AceView (NCBI)TREML2
Genatlas (Paris)TREML2
WikiGenes79865
SOURCE (Princeton)TREML2
Genetics Home Reference (NIH)TREML2
Genomic and cartography
GoldenPath hg38 (UCSC)TREML2  -     chr6:41189749-41201187 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TREML2  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblTREML2 - 6p21.1 [CytoView hg19]  TREML2 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBITREML2 [Mapview hg19]  TREML2 [Mapview hg38]
OMIM609715   
Gene and transcription
Genbank (Entrez)AF534824 AJ420509 AK023755 AY358171 BC125078
RefSeq transcript (Entrez)NM_024807
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TREML2
Cluster EST : UnigeneHs.164797 [ NCBI ]
CGAP (NCI)Hs.164797
Alternative Splicing GalleryENSG00000112195
Gene ExpressionTREML2 [ NCBI-GEO ]   TREML2 [ EBI - ARRAY_EXPRESS ]   TREML2 [ SEEK ]   TREML2 [ MEM ]
Gene Expression Viewer (FireBrowse)TREML2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79865
GTEX Portal (Tissue expression)TREML2
Human Protein AtlasENSG00000112195-TREML2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T2D2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T2D2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T2D2
Splice isoforms : SwissVarQ5T2D2
PhosPhoSitePlusQ5T2D2
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TREML2
DMDM Disease mutations79865
Blocks (Seattle)TREML2
SuperfamilyQ5T2D2
Human Protein Atlas [tissue]ENSG00000112195-TREML2 [tissue]
Peptide AtlasQ5T2D2
HPRD11646
IPIIPI00947138   
Protein Interaction databases
DIP (DOE-UCLA)Q5T2D2
IntAct (EBI)Q5T2D2
FunCoupENSG00000112195
BioGRIDTREML2
STRING (EMBL)TREML2
ZODIACTREML2
Ontologies - Pathways
QuickGOQ5T2D2
Ontology : AmiGOreceptor activity  protein binding  plasma membrane  cell surface  integral component of membrane  T cell activation  regulation of immune response  
Ontology : EGO-EBIreceptor activity  protein binding  plasma membrane  cell surface  integral component of membrane  T cell activation  regulation of immune response  
NDEx NetworkTREML2
Atlas of Cancer Signalling NetworkTREML2
Wikipedia pathwaysTREML2
Orthology - Evolution
OrthoDB79865
GeneTree (enSembl)ENSG00000112195
Phylogenetic Trees/Animal Genes : TreeFamTREML2
HOVERGENQ5T2D2
HOGENOMQ5T2D2
Homologs : HomoloGeneTREML2
Homology/Alignments : Family Browser (UCSC)TREML2
Gene fusions - Rearrangements
Fusion : QuiverTREML2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTREML2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TREML2
dbVarTREML2
ClinVarTREML2
1000_GenomesTREML2 
Exome Variant ServerTREML2
ExAC (Exome Aggregation Consortium)ENSG00000112195
GNOMAD BrowserENSG00000112195
Varsome BrowserTREML2
Genetic variants : HAPMAP79865
Genomic Variants (DGV)TREML2 [DGVbeta]
DECIPHERTREML2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTREML2 
Mutations
ICGC Data PortalTREML2 
TCGA Data PortalTREML2 
Broad Tumor PortalTREML2
OASIS PortalTREML2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTREML2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTREML2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TREML2
DgiDB (Drug Gene Interaction Database)TREML2
DoCM (Curated mutations)TREML2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TREML2 (select a term)
intoGenTREML2
Cancer3DTREML2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609715   
Orphanet
DisGeNETTREML2
MedgenTREML2
Genetic Testing Registry TREML2
NextProtQ5T2D2 [Medical]
TSGene79865
GENETestsTREML2
Target ValidationTREML2
Huge Navigator TREML2 [HugePedia]
snp3D : Map Gene to Disease79865
BioCentury BCIQTREML2
ClinGenTREML2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79865
Chemical/Pharm GKB GenePA134921444
Clinical trialTREML2
Miscellaneous
canSAR (ICR)TREML2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTREML2
EVEXTREML2
GoPubMedTREML2
iHOPTREML2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:36:31 CEST 2018

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