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TREML4 (triggering receptor expressed on myeloid cells like 4)

Identity

Alias_namestriggering receptor expressed on myeloid cells-like 4
Alias_symbol (synonym)TLT4
Other aliasTLT-4
HGNC (Hugo) TREML4
LocusID (NCBI) 285852
Atlas_Id 75135
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41228324 and ends at 41238382 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TREML4   30807
Cards
Entrez_Gene (NCBI)TREML4  285852  triggering receptor expressed on myeloid cells like 4
AliasesTLT-4; TLT4
GeneCards (Weizmann)TREML4
Ensembl hg19 (Hinxton)ENSG00000188056 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188056 [Gene_View]  ENSG00000188056 [Sequence]  chr6:41228324-41238382 [Contig_View]  TREML4 [Vega]
ICGC DataPortalENSG00000188056
TCGA cBioPortalTREML4
AceView (NCBI)TREML4
Genatlas (Paris)TREML4
WikiGenes285852
SOURCE (Princeton)TREML4
Genetics Home Reference (NIH)TREML4
Genomic and cartography
GoldenPath hg38 (UCSC)TREML4  -     chr6:41228324-41238382 +  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TREML4  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblTREML4 - 6p21.1 [CytoView hg19]  TREML4 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBITREML4 [Mapview hg19]  TREML4 [Mapview hg38]
OMIM614664   
Gene and transcription
Genbank (Entrez)AF534826 AK090633 AY358271 BC101780 BC105101
RefSeq transcript (Entrez)NM_198153
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TREML4
Cluster EST : UnigeneHs.434181 [ NCBI ]
CGAP (NCI)Hs.434181
Alternative Splicing GalleryENSG00000188056
Gene ExpressionTREML4 [ NCBI-GEO ]   TREML4 [ EBI - ARRAY_EXPRESS ]   TREML4 [ SEEK ]   TREML4 [ MEM ]
Gene Expression Viewer (FireBrowse)TREML4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)285852
GTEX Portal (Tissue expression)TREML4
Human Protein AtlasENSG00000188056-TREML4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UXN2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UXN2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UXN2
Splice isoforms : SwissVarQ6UXN2
PhosPhoSitePlusQ6UXN2
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)TREML4
DMDM Disease mutations285852
Blocks (Seattle)TREML4
SuperfamilyQ6UXN2
Human Protein Atlas [tissue]ENSG00000188056-TREML4 [tissue]
Peptide AtlasQ6UXN2
HPRD15548
IPIIPI00414495   IPI00478677   IPI00942070   IPI00947139   
Protein Interaction databases
DIP (DOE-UCLA)Q6UXN2
IntAct (EBI)Q6UXN2
FunCoupENSG00000188056
BioGRIDTREML4
STRING (EMBL)TREML4
ZODIACTREML4
Ontologies - Pathways
QuickGOQ6UXN2
Ontology : AmiGOextracellular region  plasma membrane  regulation of immune response  
Ontology : EGO-EBIextracellular region  plasma membrane  regulation of immune response  
NDEx NetworkTREML4
Atlas of Cancer Signalling NetworkTREML4
Wikipedia pathwaysTREML4
Orthology - Evolution
OrthoDB285852
GeneTree (enSembl)ENSG00000188056
Phylogenetic Trees/Animal Genes : TreeFamTREML4
HOVERGENQ6UXN2
HOGENOMQ6UXN2
Homologs : HomoloGeneTREML4
Homology/Alignments : Family Browser (UCSC)TREML4
Gene fusions - Rearrangements
Fusion : QuiverTREML4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTREML4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TREML4
dbVarTREML4
ClinVarTREML4
1000_GenomesTREML4 
Exome Variant ServerTREML4
ExAC (Exome Aggregation Consortium)ENSG00000188056
GNOMAD BrowserENSG00000188056
Varsome BrowserTREML4
Genetic variants : HAPMAP285852
Genomic Variants (DGV)TREML4 [DGVbeta]
DECIPHERTREML4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTREML4 
Mutations
ICGC Data PortalTREML4 
TCGA Data PortalTREML4 
Broad Tumor PortalTREML4
OASIS PortalTREML4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTREML4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTREML4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TREML4
DgiDB (Drug Gene Interaction Database)TREML4
DoCM (Curated mutations)TREML4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TREML4 (select a term)
intoGenTREML4
Cancer3DTREML4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614664   
Orphanet
DisGeNETTREML4
MedgenTREML4
Genetic Testing Registry TREML4
NextProtQ6UXN2 [Medical]
TSGene285852
GENETestsTREML4
Target ValidationTREML4
Huge Navigator TREML4 [HugePedia]
snp3D : Map Gene to Disease285852
BioCentury BCIQTREML4
ClinGenTREML4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD285852
Chemical/Pharm GKB GenePA134993202
Clinical trialTREML4
Miscellaneous
canSAR (ICR)TREML4 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTREML4
EVEXTREML4
GoPubMedTREML4
iHOPTREML4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:36:31 CEST 2018

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