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TREML4 (triggering receptor expressed on myeloid cells like 4)

Identity

Alias (NCBI)TLT-4
TLT4
HGNC (Hugo) TREML4
HGNC Alias symbTLT4
HGNC Alias nameTREM like transcript 4
HGNC Previous nametriggering receptor expressed on myeloid cells-like 4
LocusID (NCBI) 285852
Atlas_Id 75135
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41228349 and ends at 41238882 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TREML4   30807
Cards
Entrez_Gene (NCBI)TREML4    triggering receptor expressed on myeloid cells like 4
AliasesTLT-4; TLT4
GeneCards (Weizmann)TREML4
Ensembl hg19 (Hinxton)ENSG00000188056 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188056 [Gene_View]  ENSG00000188056 [Sequence]  chr6:41228349-41238882 [Contig_View]  TREML4 [Vega]
ICGC DataPortalENSG00000188056
TCGA cBioPortalTREML4
AceView (NCBI)TREML4
Genatlas (Paris)TREML4
SOURCE (Princeton)TREML4
Genetics Home Reference (NIH)TREML4
Genomic and cartography
GoldenPath hg38 (UCSC)TREML4  -     chr6:41228349-41238882 +  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TREML4  -     6p21.1   [Description]    (hg19-Feb_2009)
GoldenPathTREML4 - 6p21.1 [CytoView hg19]  TREML4 - 6p21.1 [CytoView hg38]
ImmunoBaseENSG00000188056
Genome Data Viewer NCBITREML4 [Mapview hg19]  
OMIM614664   
Gene and transcription
Genbank (Entrez)AF534826 AK090633 AY358271 BC101780 BC105101
RefSeq transcript (Entrez)NM_198153
Consensus coding sequences : CCDS (NCBI)TREML4
Gene ExpressionTREML4 [ NCBI-GEO ]   TREML4 [ EBI - ARRAY_EXPRESS ]   TREML4 [ SEEK ]   TREML4 [ MEM ]
Gene Expression Viewer (FireBrowse)TREML4 [ Firebrowse - Broad ]
GenevisibleExpression of TREML4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)285852
GTEX Portal (Tissue expression)TREML4
Human Protein AtlasENSG00000188056-TREML4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UXN2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UXN2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UXN2
PhosPhoSitePlusQ6UXN2
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)TREML4
SuperfamilyQ6UXN2
AlphaFold pdb e-kbQ6UXN2   
Human Protein Atlas [tissue]ENSG00000188056-TREML4 [tissue]
HPRD15548
Protein Interaction databases
DIP (DOE-UCLA)Q6UXN2
IntAct (EBI)Q6UXN2
BioGRIDTREML4
STRING (EMBL)TREML4
ZODIACTREML4
Ontologies - Pathways
QuickGOQ6UXN2
Ontology : AmiGOextracellular region  plasma membrane  cell surface  positive regulation of toll-like receptor 7 signaling pathway  positive regulation of toll-like receptor 7 signaling pathway  signaling receptor activity  innate immune response  regulation of immune response  
Ontology : EGO-EBIextracellular region  plasma membrane  cell surface  positive regulation of toll-like receptor 7 signaling pathway  positive regulation of toll-like receptor 7 signaling pathway  signaling receptor activity  innate immune response  regulation of immune response  
NDEx NetworkTREML4
Atlas of Cancer Signalling NetworkTREML4
Wikipedia pathwaysTREML4
Orthology - Evolution
OrthoDB285852
GeneTree (enSembl)ENSG00000188056
Phylogenetic Trees/Animal Genes : TreeFamTREML4
Homologs : HomoloGeneTREML4
Homology/Alignments : Family Browser (UCSC)TREML4
Gene fusions - Rearrangements
Fusion : QuiverTREML4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTREML4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TREML4
dbVarTREML4
ClinVarTREML4
MonarchTREML4
1000_GenomesTREML4 
Exome Variant ServerTREML4
GNOMAD BrowserENSG00000188056
Varsome BrowserTREML4
ACMGTREML4 variants
VarityQ6UXN2
Genomic Variants (DGV)TREML4 [DGVbeta]
DECIPHERTREML4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTREML4 
Mutations
ICGC Data PortalTREML4 
TCGA Data PortalTREML4 
Broad Tumor PortalTREML4
OASIS PortalTREML4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTREML4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTREML4
Mutations and Diseases : HGMDTREML4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTREML4
DgiDB (Drug Gene Interaction Database)TREML4
DoCM (Curated mutations)TREML4
CIViC (Clinical Interpretations of Variants in Cancer)TREML4
Cancer3DTREML4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614664   
Orphanet
DisGeNETTREML4
MedgenTREML4
Genetic Testing Registry TREML4
NextProtQ6UXN2 [Medical]
GENETestsTREML4
Target ValidationTREML4
Huge Navigator TREML4 [HugePedia]
ClinGenTREML4
Clinical trials, drugs, therapy
MyCancerGenomeTREML4
Protein Interactions : CTDTREML4
Pharm GKB GenePA134993202
PharosQ6UXN2
Clinical trialTREML4
Miscellaneous
canSAR (ICR)TREML4
HarmonizomeTREML4
DataMed IndexTREML4
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTREML4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:26:50 CEST 2021

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