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TRIM14 (tripartite motif containing 14)

Identity

Alias (NCBI)-
HGNC (Hugo) TRIM14
HGNC Alias symbKIAA0129
HGNC Previous nametripartite motif-containing 14
LocusID (NCBI) 9830
Atlas_Id 56768
Location 9q22.33  [Link to chromosome band 9q22]
Location_base_pair Starts at 98084353 and ends at 98119222 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ABCA2 (9q34.3) / TRIM14 (9q22.33)ADI1 (2p25.3) / TRIM14 (9q22.33)RUVBL1 (3q21.3) / TRIM14 (9q22.33)
TRIM14 (9q22.33) / PATL1 (11q12.1)TRIM14 (9q22.33) / TRIM14 (9q22.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRIM14   16283
Cards
Entrez_Gene (NCBI)TRIM14    tripartite motif containing 14
Aliases
GeneCards (Weizmann)TRIM14
Ensembl hg19 (Hinxton)ENSG00000106785 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106785 [Gene_View]  ENSG00000106785 [Sequence]  chr9:98084353-98119222 [Contig_View]  TRIM14 [Vega]
ICGC DataPortalENSG00000106785
TCGA cBioPortalTRIM14
AceView (NCBI)TRIM14
Genatlas (Paris)TRIM14
SOURCE (Princeton)TRIM14
Genetics Home Reference (NIH)TRIM14
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM14  -     chr9:98084353-98119222 -  9q22.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM14  -     9q22.33   [Description]    (hg19-Feb_2009)
GoldenPathTRIM14 - 9q22.33 [CytoView hg19]  TRIM14 - 9q22.33 [CytoView hg38]
ImmunoBaseENSG00000106785
Genome Data Viewer NCBITRIM14 [Mapview hg19]  
OMIM606556   
Gene and transcription
Genbank (Entrez)AA469446 AF220130 AF220131 AK055833 AK097480
RefSeq transcript (Entrez)NM_014788 NM_033219 NM_033220 NM_033221
Consensus coding sequences : CCDS (NCBI)TRIM14
Gene ExpressionTRIM14 [ NCBI-GEO ]   TRIM14 [ EBI - ARRAY_EXPRESS ]   TRIM14 [ SEEK ]   TRIM14 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM14 [ Firebrowse - Broad ]
GenevisibleExpression of TRIM14 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9830
GTEX Portal (Tissue expression)TRIM14
Human Protein AtlasENSG00000106785-TRIM14 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14142   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14142  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14142
PhosPhoSitePlusQ14142
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_BBOX (PS50119)   
Domains : Interpro (EBI)B30.2/SPRY    B30.2/SPRY_sf    Butyrophylin_SPRY    ConA-like_dom_sf    PRY    SPRY_dom    SPRY_PRY_TRIM14    Znf_B-box   
Domain families : Pfam (Sanger)PRY (PF13765)    SPRY (PF00622)    zf-B_box (PF00643)   
Domain families : Pfam (NCBI)pfam13765    pfam00622    pfam00643   
Domain families : Smart (EMBL)BBOX (SM00336)  PRY (SM00589)  SPRY (SM00449)  
Conserved Domain (NCBI)TRIM14
PDB (RSDB)6JBM   
PDB Europe6JBM   
PDB (PDBSum)6JBM   
PDB (IMB)6JBM   
Structural Biology KnowledgeBase6JBM   
SCOP (Structural Classification of Proteins)6JBM   
CATH (Classification of proteins structures)6JBM   
SuperfamilyQ14142
AlphaFold pdb e-kbQ14142   
Human Protein Atlas [tissue]ENSG00000106785-TRIM14 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q14142
IntAct (EBI)Q14142
BioGRIDTRIM14
STRING (EMBL)TRIM14
ZODIACTRIM14
Ontologies - Pathways
QuickGOQ14142
Ontology : AmiGOprotein polyubiquitination  transcription coactivator activity  protein binding  nucleoplasm  cytoplasm  mitochondrial outer membrane  cytosol  zinc ion binding  regulation of gene expression  positive regulation of autophagy  protein ubiquitination  protein kinase binding  regulation of protein localization  negative regulation of viral transcription  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  innate immune response  phagocytic vesicle  positive regulation of transcription, DNA-templated  regulation of viral entry into host cell  positive regulation of DNA-binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  positive regulation of NF-kappaB transcription factor activity  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein polyubiquitination  transcription coactivator activity  protein binding  nucleoplasm  cytoplasm  mitochondrial outer membrane  cytosol  zinc ion binding  regulation of gene expression  positive regulation of autophagy  protein ubiquitination  protein kinase binding  regulation of protein localization  negative regulation of viral transcription  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  innate immune response  phagocytic vesicle  positive regulation of transcription, DNA-templated  regulation of viral entry into host cell  positive regulation of DNA-binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  positive regulation of NF-kappaB transcription factor activity  ubiquitin protein ligase activity  
NDEx NetworkTRIM14
Atlas of Cancer Signalling NetworkTRIM14
Wikipedia pathwaysTRIM14
Orthology - Evolution
OrthoDB9830
GeneTree (enSembl)ENSG00000106785
Phylogenetic Trees/Animal Genes : TreeFamTRIM14
Homologs : HomoloGeneTRIM14
Homology/Alignments : Family Browser (UCSC)TRIM14
Gene fusions - Rearrangements
Fusion : QuiverTRIM14
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM14
dbVarTRIM14
ClinVarTRIM14
MonarchTRIM14
1000_GenomesTRIM14 
Exome Variant ServerTRIM14
GNOMAD BrowserENSG00000106785
Varsome BrowserTRIM14
ACMGTRIM14 variants
VarityQ14142
Genomic Variants (DGV)TRIM14 [DGVbeta]
DECIPHERTRIM14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM14 
Mutations
ICGC Data PortalTRIM14 
TCGA Data PortalTRIM14 
Broad Tumor PortalTRIM14
OASIS PortalTRIM14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM14  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIM14
Mutations and Diseases : HGMDTRIM14
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRIM14
DgiDB (Drug Gene Interaction Database)TRIM14
DoCM (Curated mutations)TRIM14
CIViC (Clinical Interpretations of Variants in Cancer)TRIM14
Cancer3DTRIM14
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606556   
Orphanet
DisGeNETTRIM14
MedgenTRIM14
Genetic Testing Registry TRIM14
NextProtQ14142 [Medical]
GENETestsTRIM14
Target ValidationTRIM14
Huge Navigator TRIM14 [HugePedia]
ClinGenTRIM14
Clinical trials, drugs, therapy
MyCancerGenomeTRIM14
Protein Interactions : CTDTRIM14
Pharm GKB GenePA38113
PharosQ14142
Clinical trialTRIM14
Miscellaneous
canSAR (ICR)TRIM14
HarmonizomeTRIM14
DataMed IndexTRIM14
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRIM14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:17 CEST 2021

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