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TRIM15 (tripartite motif containing 15)

Identity

Alias_namesZNF178
zinc finger protein 178
tripartite motif-containing 15
Alias_symbol (synonym)ZNFB7
RNF93
Other alias
HGNC (Hugo) TRIM15
LocusID (NCBI) 89870
Atlas_Id 55228
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 30163206 and ends at 30172696 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MPDU1 (17p13.1) / TRIM15 (6p22.1)TRIM15 (6p22.1) / RALY (20q11.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRIM15   16284
Cards
Entrez_Gene (NCBI)TRIM15  89870  tripartite motif containing 15
AliasesRNF93; ZNF178; ZNFB7
GeneCards (Weizmann)TRIM15
Ensembl hg19 (Hinxton)ENSG00000204610 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204610 [Gene_View]  ENSG00000204610 [Sequence]  chr6:30163206-30172696 [Contig_View]  TRIM15 [Vega]
ICGC DataPortalENSG00000204610
TCGA cBioPortalTRIM15
AceView (NCBI)TRIM15
Genatlas (Paris)TRIM15
WikiGenes89870
SOURCE (Princeton)TRIM15
Genetics Home Reference (NIH)TRIM15
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM15  -     chr6:30163206-30172696 +  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM15  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblTRIM15 - 6p22.1 [CytoView hg19]  TRIM15 - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBITRIM15 [Mapview hg19]  TRIM15 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF220132 AF220133 AI739162 AK290280 AK291853
RefSeq transcript (Entrez)NM_033229 NM_052812
RefSeq genomic (Entrez)NC_000006 NT_113891 NT_167244 NT_167245 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)TRIM15
Cluster EST : UnigeneHs.606488 [ NCBI ]
CGAP (NCI)Hs.606488
Alternative Splicing GalleryENSG00000204610
Gene ExpressionTRIM15 [ NCBI-GEO ]   TRIM15 [ EBI - ARRAY_EXPRESS ]   TRIM15 [ SEEK ]   TRIM15 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)89870
GTEX Portal (Tissue expression)TRIM15
Human Protein AtlasENSG00000204610-TRIM15 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C019   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C019  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C019
Splice isoforms : SwissVarQ9C019
PhosPhoSitePlusQ9C019
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    Butyrophylin_SPRY    ConA-like_dom_sf    PRY    SPRY_dom    Znf_B-box    Znf_C3HC4_RING-type    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)PRY (PF13765)    SPRY (PF00622)    zf-B_box (PF00643)    zf-C3HC4 (PF00097)   
Domain families : Pfam (NCBI)pfam13765    pfam00622    pfam00643    pfam00097   
Domain families : Smart (EMBL)BBOX (SM00336)  PRY (SM00589)  RING (SM00184)  SPRY (SM00449)  
Conserved Domain (NCBI)TRIM15
DMDM Disease mutations89870
Blocks (Seattle)TRIM15
SuperfamilyQ9C019
Human Protein Atlas [tissue]ENSG00000204610-TRIM15 [tissue]
Peptide AtlasQ9C019
HPRD15551
IPIIPI00299584   IPI00299585   IPI00514140   IPI00034456   IPI00477973   IPI01020953   IPI00788628   IPI00894291   
Protein Interaction databases
DIP (DOE-UCLA)Q9C019
IntAct (EBI)Q9C019
FunCoupENSG00000204610
BioGRIDTRIM15
STRING (EMBL)TRIM15
ZODIACTRIM15
Ontologies - Pathways
QuickGOQ9C019
Ontology : AmiGOprotein binding  intracellular  mesodermal cell fate determination  zinc ion binding  positive regulation of type I interferon production  innate immune response  positive regulation of DNA-binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  positive regulation of RIG-I signaling pathway  negative regulation of intracellular transport of viral material  negative regulation of viral release from host cell  negative regulation of viral release from host cell  
Ontology : EGO-EBIprotein binding  intracellular  mesodermal cell fate determination  zinc ion binding  positive regulation of type I interferon production  innate immune response  positive regulation of DNA-binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  positive regulation of RIG-I signaling pathway  negative regulation of intracellular transport of viral material  negative regulation of viral release from host cell  negative regulation of viral release from host cell  
NDEx NetworkTRIM15
Atlas of Cancer Signalling NetworkTRIM15
Wikipedia pathwaysTRIM15
Orthology - Evolution
OrthoDB89870
GeneTree (enSembl)ENSG00000204610
Phylogenetic Trees/Animal Genes : TreeFamTRIM15
HOVERGENQ9C019
HOGENOMQ9C019
Homologs : HomoloGeneTRIM15
Homology/Alignments : Family Browser (UCSC)TRIM15
Gene fusions - Rearrangements
Fusion : QuiverTRIM15
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM15
dbVarTRIM15
ClinVarTRIM15
1000_GenomesTRIM15 
Exome Variant ServerTRIM15
ExAC (Exome Aggregation Consortium)ENSG00000204610
GNOMAD BrowserENSG00000204610
Varsome BrowserTRIM15
Genetic variants : HAPMAP89870
Genomic Variants (DGV)TRIM15 [DGVbeta]
DECIPHERTRIM15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM15 
Mutations
ICGC Data PortalTRIM15 
TCGA Data PortalTRIM15 
Broad Tumor PortalTRIM15
OASIS PortalTRIM15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRIM15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM15
DgiDB (Drug Gene Interaction Database)TRIM15
DoCM (Curated mutations)TRIM15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM15 (select a term)
intoGenTRIM15
Cancer3DTRIM15(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTRIM15
MedgenTRIM15
Genetic Testing Registry TRIM15
NextProtQ9C019 [Medical]
TSGene89870
GENETestsTRIM15
Target ValidationTRIM15
Huge Navigator TRIM15 [HugePedia]
snp3D : Map Gene to Disease89870
BioCentury BCIQTRIM15
ClinGenTRIM15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD89870
Chemical/Pharm GKB GenePA38114
Clinical trialTRIM15
Miscellaneous
canSAR (ICR)TRIM15 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIM15
EVEXTRIM15
GoPubMedTRIM15
iHOPTRIM15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:46:45 CET 2018

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