Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6737
MIM: 109092
HGNC: 11312
Ensembl: ENSG00000132109
Variants:
dbSNP: 6737
ClinVar: 6737
TCGA: ENSG00000132109
COSMIC: TRIM21
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000132109 | ENST00000254436 | P19474 |
| ENSG00000132109 | ENST00000533692 | H0YDP8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37782406 | 2024 | FGF19 promotes nasopharyngeal carcinoma progression by inducing angiogenesis via inhibiting TRIM21-mediated ANXA2 ubiquitination. | 0 |
| 37897508 | 2024 | N6-methyladenosine modification of OIP5-AS1 promotes glycolysis, tumorigenesis, and metastasis of gastric cancer by inhibiting Trim21-mediated hnRNPA1 ubiquitination and degradation. | 2 |
| 38331257 | 2024 | Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response. | 2 |
| 38475938 | 2024 | TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway. | 2 |
| 38480558 | 2024 | TRIM21 reduces H1N1-induced inflammation and apoptosis by regulating the TBK1-IRF3 signaling pathway in A549 cells. | 1 |
| 38542289 | 2024 | TRIM21 Promotes Oxidative Stress and Ferroptosis through the SQSTM1-NRF2-KEAP1 Axis to Increase the Titers of H5N1 Highly Pathogenic Avian Influenza Virus. | 1 |
| 38697462 | 2024 | TRIM21-mediated ubiquitylation of TAT suppresses liver metastasis in gallbladder cancer. | 0 |
| 38702792 | 2024 | The deubiquitinase USP7 and E3 ligase TRIM21 regulate vasculogenic mimicry and malignant progression of RMS by balancing SNAI2 homeostasis. | 0 |
| 38938560 | 2024 | TRIM21 and Fc-engineered antibodies: decoding its complex antibody binding mode with implications for viral neutralization. | 0 |
| 37782406 | 2024 | FGF19 promotes nasopharyngeal carcinoma progression by inducing angiogenesis via inhibiting TRIM21-mediated ANXA2 ubiquitination. | 0 |
| 37897508 | 2024 | N6-methyladenosine modification of OIP5-AS1 promotes glycolysis, tumorigenesis, and metastasis of gastric cancer by inhibiting Trim21-mediated hnRNPA1 ubiquitination and degradation. | 2 |
| 38331257 | 2024 | Systems genetics of influenza A virus-infected mice identifies TRIM21 as a critical regulator of pulmonary innate immune response. | 2 |
| 38475938 | 2024 | TRIM21 is critical in regulating hepatocellular carcinoma growth and response to therapy by altering the MST1/YAP pathway. | 2 |
| 38480558 | 2024 | TRIM21 reduces H1N1-induced inflammation and apoptosis by regulating the TBK1-IRF3 signaling pathway in A549 cells. | 1 |
| 38542289 | 2024 | TRIM21 Promotes Oxidative Stress and Ferroptosis through the SQSTM1-NRF2-KEAP1 Axis to Increase the Titers of H5N1 Highly Pathogenic Avian Influenza Virus. | 1 |
Citation
Dessen P
TRIM21 (tripartite motif containing 21)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46025/trim21
