Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA
Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

Donate (in Euros)

Donate (in US Dollars)

TRIM22 (tripartite motif containing 22)

Identity

Other namesGPSTAF50
RNF94
STAF50
HGNC (Hugo) TRIM22
LocusID (NCBI) 10346
Location 11p15.4
Location_base_pair Starts at 5710817 and ends at 5732093 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)TRIM22   16379
Cards
Entrez_Gene (NCBI)TRIM22  10346  tripartite motif containing 22
GeneCards (Weizmann)TRIM22
Ensembl hg19 (Hinxton)ENSG00000132274 [Gene_View]  chr11:5710817-5732093 [Contig_View]  TRIM22 [Vega]
Ensembl hg38 (Hinxton)ENSG00000132274 [Gene_View]  chr11:5710817-5732093 [Contig_View]  TRIM22 [Vega]
ICGC DataPortalENSG00000132274
cBioPortalTRIM22
AceView (NCBI)TRIM22
Genatlas (Paris)TRIM22
WikiGenes10346
SOURCE (Princeton)TRIM22
Genomic and cartography
GoldenPath hg19 (UCSC)TRIM22  -     chr11:5710817-5732093 +  11p15.4   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TRIM22  -     11p15.4   [Description]    (hg38-Dec_2013)
EnsemblTRIM22 - 11p15.4 [CytoView hg19]  TRIM22 - 11p15.4 [CytoView hg38]
Mapping of homologs : NCBITRIM22 [Mapview hg19]  TRIM22 [Mapview hg38]
OMIM606559   
Gene and transcription
Genbank (Entrez)AK290434 AK298715 AK298934 AK301192 AK308221
RefSeq transcript (Entrez)NM_001199573 NM_006074
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NT_009237 NW_001838021 NW_004929378
Consensus coding sequences : CCDS (NCBI)TRIM22
Cluster EST : UnigeneHs.733231 [ NCBI ]
CGAP (NCI)Hs.733231
Alternative Splicing : Fast-db (Paris)GSHG0004586
Alternative Splicing GalleryENSG00000132274
Gene ExpressionTRIM22 [ NCBI-GEO ]     TRIM22 [ SEEK ]   TRIM22 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYM9 (Uniprot)
NextProtQ8IYM9  [Medical]
With graphics : InterProQ8IYM9
Splice isoforms : SwissVarQ8IYM9 (Swissvar)
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    Butyrophylin    ConA-like_lec_gl_sf    SPRY_rcpt    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Related proteins : CluSTrQ8IYM9
Domain families : Pfam (Sanger)SPRY (PF00622)    zf-B_box (PF00643)   
Domain families : Pfam (NCBI)pfam00622    pfam00643   
Domain families : Smart (EMBL)BBOX (SM00336)  RING (SM00184)  
DMDM Disease mutations10346
Blocks (Seattle)Q8IYM9
Human Protein AtlasENSG00000132274
Peptide AtlasQ8IYM9
HPRD05951
IPIIPI00477812   IPI00477398   IPI00942007   IPI00748802   IPI00239700   IPI00884241   IPI00657693   IPI00893225   IPI00927497   IPI00927753   IPI00924480   
Protein Interaction databases
DIP (DOE-UCLA)Q8IYM9
IntAct (EBI)Q8IYM9
FunCoupENSG00000132274
BioGRIDTRIM22
IntegromeDBTRIM22
STRING (EMBL)TRIM22
Ontologies - Pathways
QuickGOQ8IYM9
Ontology : AmiGOsequence-specific DNA binding transcription factor activity  transcription corepressor activity  nucleus  nucleolus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  immune response  zinc ion binding  response to virus  Cajal body  viral process  protein ubiquitination  nuclear speck  ligase activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of sequence-specific DNA binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  defense response to virus  protein trimerization  
Ontology : EGO-EBIsequence-specific DNA binding transcription factor activity  transcription corepressor activity  nucleus  nucleolus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  immune response  zinc ion binding  response to virus  Cajal body  viral process  protein ubiquitination  nuclear speck  ligase activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of sequence-specific DNA binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  defense response to virus  protein trimerization  
Protein Interaction DatabaseTRIM22
DoCM (Curated mutations)TRIM22
Wikipedia pathwaysTRIM22
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerTRIM22 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM22
dbVarTRIM22
ClinVarTRIM22
1000_GenomesTRIM22 
Exome Variant ServerTRIM22
SNP (GeneSNP Utah)TRIM22
SNP : HGBaseTRIM22
Genetic variants : HAPMAPTRIM22
Genomic Variants (DGV)TRIM22 [DGVbeta]
Mutations
ICGC Data PortalENSG00000132274 
Somatic Mutations in Cancer : COSMICTRIM22 
CONAN: Copy Number AnalysisTRIM22 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)11:5710817-5732093
Mutations and Diseases : HGMDTRIM22
OMIM606559   
MedgenTRIM22
NextProtQ8IYM9 [Medical]
GENETestsTRIM22
Disease Genetic AssociationTRIM22
Huge Navigator TRIM22 [HugePedia]  TRIM22 [HugeCancerGEM]
snp3D : Map Gene to Disease10346
DGIdb (Drug Gene Interaction db)TRIM22
General knowledge
Homologs : HomoloGeneTRIM22
Homology/Alignments : Family Browser (UCSC)TRIM22
Phylogenetic Trees/Animal Genes : TreeFamTRIM22
Chemical/Protein Interactions : CTD10346
Chemical/Pharm GKB GenePA38129
Clinical trialTRIM22
Cancer Resource (Charite)ENSG00000132274
Other databases
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
CoreMineTRIM22
GoPubMedTRIM22
iHOPTRIM22
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 19:10:11 CET 2015
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.