| Nomenclature |
|---|
| HGNC (Hugo) | TRIM22 16379 |
| Cards |
|---|
| Entrez_Gene (NCBI) | TRIM22 10346 tripartite motif containing 22 |
| Aliases | GPSTAF50; RNF94; STAF50 |
| GeneCards (Weizmann) | TRIM22 |
| Ensembl hg19 (Hinxton) | ENSG00000132274 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000132274 [Gene_View] chr11:5689587-5710863 [Contig_View] TRIM22 [Vega] |
| ICGC DataPortal | ENSG00000132274 |
| TCGA cBioPortal | TRIM22 |
| AceView (NCBI) | TRIM22 |
| Genatlas (Paris) | TRIM22 |
| WikiGenes | 10346 |
| SOURCE (Princeton) | TRIM22 |
| Genetics Home Reference (NIH) | TRIM22 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | TRIM22 - chr11:5689587-5710863 + 11p15.4 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | TRIM22 - 11p15.4 [Description] (hg19-Feb_2009) |
| Ensembl | TRIM22 - 11p15.4 [CytoView hg19] TRIM22 - 11p15.4 [CytoView hg38] |
| Mapping of homologs : NCBI | TRIM22 [Mapview hg19] TRIM22 [Mapview hg38] |
| OMIM | 606559 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK290434 AK298715 AK298934 AK301192 AK308221 |
| RefSeq transcript (Entrez) | NM_001199573 NM_006074 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | TRIM22 |
| Cluster EST : Unigene | Hs.733231 [ NCBI ] |
| CGAP (NCI) | Hs.733231 |
| Alternative Splicing Gallery | ENSG00000132274 |
| Gene Expression | TRIM22 [ NCBI-GEO ] TRIM22 [ EBI - ARRAY_EXPRESS ]
TRIM22 [ SEEK ] TRIM22 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | TRIM22 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevisible | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 10346 |
| GTEX Portal (Tissue expression) | TRIM22 |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q8IYM9 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q8IYM9 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q8IYM9 |
| Splice isoforms : SwissVar | Q8IYM9 |
| Catalytic activity : Enzyme | 2.3.2.27 [ Enzyme-Expasy ] 2.3.2.272.3.2.27 [ IntEnz-EBI ] 2.3.2.27 [ BRENDA ] 2.3.2.27 [ KEGG ] |
| PhosPhoSitePlus | Q8IYM9 |
| Domaine pattern : Prosite (Expaxy) | B302_SPRY (PS50188) ZF_BBOX (PS50119) ZF_RING_1 (PS00518) ZF_RING_2 (PS50089) |
| Domains : Interpro (EBI) | B30.2/SPRY Butyrophylin ConA-like_dom SPRY_dom Znf-RING_LisH Znf_B-box Znf_RING Znf_RING/FYVE/PHD Znf_RING_CS |
| Domain families : Pfam (Sanger) | SPRY (PF00622) zf-B_box (PF00643) zf-RING_UBOX (PF13445) |
| Domain families : Pfam (NCBI) | pfam00622 pfam00643 pfam13445 |
| Domain families : Smart (EMBL) | BBOX (SM00336) RING (SM00184) SPRY (SM00449) |
| Conserved Domain (NCBI) | TRIM22 |
| DMDM Disease mutations | 10346 |
| Blocks (Seattle) | TRIM22 |
| Superfamily | Q8IYM9 |
| Human Protein Atlas | ENSG00000132274 |
| Peptide Atlas | Q8IYM9 |
| HPRD | 05951 |
| IPI | IPI00477812 IPI00477398 IPI00942007 IPI00748802 IPI00239700 IPI00884241 IPI00657693 IPI00893225 IPI00927497 IPI00927753 IPI00924480 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q8IYM9 |
| IntAct (EBI) | Q8IYM9 |
| FunCoup | ENSG00000132274 |
| BioGRID | TRIM22 |
| STRING (EMBL) | TRIM22 |
| ZODIAC | TRIM22 |
| Ontologies - Pathways |
|---|
| QuickGO | Q8IYM9 |
| Ontology : AmiGO | transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding nucleus nucleoplasm cytoplasm cytosol transcription, DNA-templated regulation of transcription, DNA-templated immune response zinc ion binding response to virus positive regulation of autophagy Cajal body protein ubiquitination nuclear body nuclear speck transferase activity protein kinase binding protein binding, bridging regulation of protein localization positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity defense response to virus interferon-gamma-mediated signaling pathway protein trimerization negative regulation of nucleic acid-templated transcription |
| Ontology : EGO-EBI | transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding nucleus nucleoplasm cytoplasm cytosol transcription, DNA-templated regulation of transcription, DNA-templated immune response zinc ion binding response to virus positive regulation of autophagy Cajal body protein ubiquitination nuclear body nuclear speck transferase activity protein kinase binding protein binding, bridging regulation of protein localization positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of sequence-specific DNA binding transcription factor activity positive regulation of NF-kappaB transcription factor activity defense response to virus interferon-gamma-mediated signaling pathway protein trimerization negative regulation of nucleic acid-templated transcription |
| NDEx Network | TRIM22 |
| Atlas of Cancer Signalling Network | TRIM22 |
| Wikipedia pathways | TRIM22 |
| Orthology - Evolution |
|---|
| OrthoDB | 10346 |
| GeneTree (enSembl) | ENSG00000132274 |
| Phylogenetic Trees/Animal Genes : TreeFam | TRIM22 |
| HOVERGEN | Q8IYM9 |
| HOGENOM | Q8IYM9 |
| Homologs : HomoloGene | TRIM22 |
| Homology/Alignments : Family Browser (UCSC) | TRIM22 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | AP2A2/TRIM22 [11p15.5/11p15.4] [t(11;11)(p15;p15)] |
| Fusion : Mitelman | HBG2/TRIM22 [11p15.4/11p15.4] [t(11;11)(p15;p15)] |
| Fusion: TCGA | AP2A2 11p15.5 TRIM22 11p15.4 HNSC |
| Fusion: TCGA | HBG2 11p15.4 TRIM22 11p15.4 HNSC |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | TRIM22 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | TRIM22 |
| dbVar | TRIM22 |
| ClinVar | TRIM22 |
| 1000_Genomes | TRIM22 |
| Exome Variant Server | TRIM22 |
| ExAC (Exome Aggregation Consortium) | TRIM22 (select the gene name) |
| Genetic variants : HAPMAP | 10346 |
| Genomic Variants (DGV) | TRIM22 [DGVbeta] |
| DECIPHER | TRIM22 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | TRIM22 |
| Mutations |
|---|
| ICGC Data Portal | TRIM22 |
| TCGA Data Portal | TRIM22 |
| Broad Tumor Portal | TRIM22 |
| OASIS Portal | TRIM22 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | TRIM22 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | TRIM22 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search TRIM22 |
| DgiDB (Drug Gene Interaction Database) | TRIM22 |
| DoCM (Curated mutations) | TRIM22 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | TRIM22 (select a term) |
| intoGen | TRIM22 |
| Cancer3D | TRIM22(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 606559 |
| Orphanet | |
| Medgen | TRIM22 |
| Genetic Testing Registry | TRIM22
|
| NextProt | Q8IYM9 [Medical] |
| TSGene | 10346 |
| GENETests | TRIM22 |
| Target Validation | TRIM22 |
| Huge Navigator |
TRIM22 [HugePedia] |
| snp3D : Map Gene to Disease | 10346 |
| BioCentury BCIQ | TRIM22 |
| ClinGen | TRIM22 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 10346 |
| Chemical/Pharm GKB Gene | PA38129 |
| Clinical trial | TRIM22 |
| Miscellaneous |
|---|
| canSAR (ICR) | TRIM22 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 57 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | TRIM22 |
| EVEX | TRIM22 |
| GoPubMed | TRIM22 |
| iHOP | TRIM22 |
