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TRIM23 (tripartite motif containing 23)

Identity

Alias (NCBI)ARD1
ARFD1
RNF46
HGNC (Hugo) TRIM23
HGNC Alias symbARD1
RNF46
HGNC Previous nameARFD1
HGNC Previous nameADP-ribosylation factor domain protein 1, 64kDa
 tripartite motif-containing 23
LocusID (NCBI) 373
Atlas_Id 53772
Location 5q12.3  [Link to chromosome band 5q12]
Location_base_pair Starts at 65589690 and ends at 65624333 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRIM23   660
Cards
Entrez_Gene (NCBI)TRIM23    tripartite motif containing 23
AliasesARD1; ARFD1; RNF46
GeneCards (Weizmann)TRIM23
Ensembl hg19 (Hinxton)ENSG00000113595 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113595 [Gene_View]  ENSG00000113595 [Sequence]  chr5:65589690-65624333 [Contig_View]  TRIM23 [Vega]
ICGC DataPortalENSG00000113595
TCGA cBioPortalTRIM23
AceView (NCBI)TRIM23
Genatlas (Paris)TRIM23
SOURCE (Princeton)TRIM23
Genetics Home Reference (NIH)TRIM23
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM23  -     chr5:65589690-65624333 -  5q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM23  -     5q12.3   [Description]    (hg19-Feb_2009)
GoldenPathTRIM23 - 5q12.3 [CytoView hg19]  TRIM23 - 5q12.3 [CytoView hg38]
ImmunoBaseENSG00000113595
Genome Data Viewer NCBITRIM23 [Mapview hg19]  
OMIM601747   
Gene and transcription
Genbank (Entrez)AF230397 AF230398 AF230399 AI679928 AK292814
RefSeq transcript (Entrez)NM_001656 NM_033227 NM_033228
Consensus coding sequences : CCDS (NCBI)TRIM23
Gene ExpressionTRIM23 [ NCBI-GEO ]   TRIM23 [ EBI - ARRAY_EXPRESS ]   TRIM23 [ SEEK ]   TRIM23 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM23 [ Firebrowse - Broad ]
GenevisibleExpression of TRIM23 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)373
GTEX Portal (Tissue expression)TRIM23
Human Protein AtlasENSG00000113595-TRIM23 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP36406   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP36406  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP36406
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP36406
Domaine pattern : Prosite (Expaxy)ARF (PS51417)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Bbox_C    P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase_ARF/SAR    Znf_B-box    Znf_C2H2_type    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)Arf (PF00025)    zf-B_box (PF00643)    zf-RING_5 (PF14634)   
Domain families : Pfam (NCBI)pfam00025    pfam00643    pfam14634   
Domain families : Smart (EMBL)BBC (SM00502)  BBOX (SM00336)  RING (SM00184)  
Conserved Domain (NCBI)TRIM23
PDB (RSDB)5VZV    5VZW   
PDB Europe5VZV    5VZW   
PDB (PDBSum)5VZV    5VZW   
PDB (IMB)5VZV    5VZW   
Structural Biology KnowledgeBase5VZV    5VZW   
SCOP (Structural Classification of Proteins)5VZV    5VZW   
CATH (Classification of proteins structures)5VZV    5VZW   
SuperfamilyP36406
AlphaFold pdb e-kbP36406   
Human Protein Atlas [tissue]ENSG00000113595-TRIM23 [tissue]
HPRD03449
Protein Interaction databases
DIP (DOE-UCLA)P36406
IntAct (EBI)P36406
BioGRIDTRIM23
STRING (EMBL)TRIM23
ZODIACTRIM23
Ontologies - Pathways
QuickGOP36406
Ontology : AmiGOGolgi membrane  GTPase activity  ubiquitin-protein transferase activity  protein binding  GTP binding  GTP binding  nucleus  cytoplasm  lysosomal membrane  lysosomal membrane  plasma membrane  intracellular protein transport  enzyme activator activity  zinc ion binding  vesicle-mediated transport  protein ubiquitination  protein ubiquitination  GDP binding  identical protein binding  innate immune response  
Ontology : EGO-EBIGolgi membrane  GTPase activity  ubiquitin-protein transferase activity  protein binding  GTP binding  GTP binding  nucleus  cytoplasm  lysosomal membrane  lysosomal membrane  plasma membrane  intracellular protein transport  enzyme activator activity  zinc ion binding  vesicle-mediated transport  protein ubiquitination  protein ubiquitination  GDP binding  identical protein binding  innate immune response  
NDEx NetworkTRIM23
Atlas of Cancer Signalling NetworkTRIM23
Wikipedia pathwaysTRIM23
Orthology - Evolution
OrthoDB373
GeneTree (enSembl)ENSG00000113595
Phylogenetic Trees/Animal Genes : TreeFamTRIM23
Homologs : HomoloGeneTRIM23
Homology/Alignments : Family Browser (UCSC)TRIM23
Gene fusions - Rearrangements
Fusion : QuiverTRIM23
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM23 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM23
dbVarTRIM23
ClinVarTRIM23
MonarchTRIM23
1000_GenomesTRIM23 
Exome Variant ServerTRIM23
GNOMAD BrowserENSG00000113595
Varsome BrowserTRIM23
ACMGTRIM23 variants
VarityP36406
Genomic Variants (DGV)TRIM23 [DGVbeta]
DECIPHERTRIM23 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM23 
Mutations
ICGC Data PortalTRIM23 
TCGA Data PortalTRIM23 
Broad Tumor PortalTRIM23
OASIS PortalTRIM23 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM23  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIM23
Mutations and Diseases : HGMDTRIM23
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRIM23
DgiDB (Drug Gene Interaction Database)TRIM23
DoCM (Curated mutations)TRIM23
CIViC (Clinical Interpretations of Variants in Cancer)TRIM23
Cancer3DTRIM23
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601747   
Orphanet
DisGeNETTRIM23
MedgenTRIM23
Genetic Testing Registry TRIM23
NextProtP36406 [Medical]
GENETestsTRIM23
Target ValidationTRIM23
Huge Navigator TRIM23 [HugePedia]
ClinGenTRIM23
Clinical trials, drugs, therapy
MyCancerGenomeTRIM23
Protein Interactions : CTDTRIM23
Pharm GKB GenePA24943
PharosP36406
Clinical trialTRIM23
Miscellaneous
canSAR (ICR)TRIM23
HarmonizomeTRIM23
DataMed IndexTRIM23
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRIM23
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:19 CEST 2021

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