Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TRIM33 (tripartite motif containing 33)

Identity

Alias_namestripartite motif-containing 33
Alias_symbol (synonym)TIF1GAMMA
FLJ11429
KIAA1113
TIFGAMMA
RFG7
TF1G
TIF1G
PTC7
Other aliasECTO
HGNC (Hugo) TRIM33
LocusID (NCBI) 51592
Atlas_Id 502
Location 1p13.2  [Link to chromosome band 1p13]
Location_base_pair Starts at 114935399 and ends at 115053781 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AFF1 (4q21.3) / TRIM33 (1p13.2)POSTN (13q13.3) / TRIM33 (1p13.2)RET (10q11.21) / TRIM33 (1p13.2)
TRIM33 (1p13.2) / COL24A1 (1p22.3)TRIM33 (1p13.2) / COLEC12 (18p11.32)TRIM33 (1p13.2) / RET (10q11.21)
TRIM33 (1p13.2) / STK17B (2q32.3)TRIM33 (1p13.2) / TRIM33 (1p13.2)RET 10q11.21 / TRIM33 1p13.2
TRIM33 1p13.2 / RET 10q11.21TRIM33 1p13.2 / COL24A1 1p22.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  Chronic Myelomonocytic Leukemia (CMML)


External links

Nomenclature
HGNC (Hugo)TRIM33   16290
Cards
Entrez_Gene (NCBI)TRIM33  51592  tripartite motif containing 33
AliasesECTO; PTC7; RFG7; TF1G; 
TIF1G; TIF1GAMMA; TIFGAMMA
GeneCards (Weizmann)TRIM33
Ensembl hg19 (Hinxton)ENSG00000197323 [Gene_View]  chr1:114935399-115053781 [Contig_View]  TRIM33 [Vega]
Ensembl hg38 (Hinxton)ENSG00000197323 [Gene_View]  chr1:114935399-115053781 [Contig_View]  TRIM33 [Vega]
ICGC DataPortalENSG00000197323
TCGA cBioPortalTRIM33
AceView (NCBI)TRIM33
Genatlas (Paris)TRIM33
WikiGenes51592
SOURCE (Princeton)TRIM33
Genetics Home Reference (NIH)TRIM33
Genomic and cartography
GoldenPath hg19 (UCSC)TRIM33  -     chr1:114935399-115053781 -  1p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TRIM33  -     1p13.2   [Description]    (hg38-Dec_2013)
EnsemblTRIM33 - 1p13.2 [CytoView hg19]  TRIM33 - 1p13.2 [CytoView hg38]
Mapping of homologs : NCBITRIM33 [Mapview hg19]  TRIM33 [Mapview hg38]
OMIM188550   605769   
Gene and transcription
Genbank (Entrez)AB029036 AB075517 AF119043 AF220136 AF220137
RefSeq transcript (Entrez)NM_015906 NM_033020
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_023287 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)TRIM33
Cluster EST : UnigeneHs.26837 [ NCBI ]
CGAP (NCI)Hs.26837
Alternative Splicing GalleryENSG00000197323
Gene ExpressionTRIM33 [ NCBI-GEO ]   TRIM33 [ EBI - ARRAY_EXPRESS ]   TRIM33 [ SEEK ]   TRIM33 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM33 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51592
GTEX Portal (Tissue expression)TRIM33
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPN9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPN9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPN9
Splice isoforms : SwissVarQ9UPN9
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ9UPN9
Domaine pattern : Prosite (Expaxy)BROMODOMAIN_2 (PS50014)    ZF_BBOX (PS50119)    ZF_PHD_1 (PS01359)    ZF_PHD_2 (PS50016)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Bbox_C    Bromodomain    Zinc_finger_PHD-type_CS    Znf_B-box    Znf_FYVE_PHD    Znf_PHD    Znf_PHD-finger    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)Bromodomain (PF00439)    PHD (PF00628)    zf-B_box (PF00643)   
Domain families : Pfam (NCBI)pfam00439    pfam00628    pfam00643   
Domain families : Smart (EMBL)BBC (SM00502)  BBOX (SM00336)  BROMO (SM00297)  PHD (SM00249)  RING (SM00184)  
Conserved Domain (NCBI)TRIM33
DMDM Disease mutations51592
Blocks (Seattle)TRIM33
PDB (SRS)3U5M    3U5N    3U5O    3U5P   
PDB (PDBSum)3U5M    3U5N    3U5O    3U5P   
PDB (IMB)3U5M    3U5N    3U5O    3U5P   
PDB (RSDB)3U5M    3U5N    3U5O    3U5P   
Structural Biology KnowledgeBase3U5M    3U5N    3U5O    3U5P   
SCOP (Structural Classification of Proteins)3U5M    3U5N    3U5O    3U5P   
CATH (Classification of proteins structures)3U5M    3U5N    3U5O    3U5P   
SuperfamilyQ9UPN9
Human Protein AtlasENSG00000197323
Peptide AtlasQ9UPN9
HPRD10423
IPIIPI00010252   IPI00221114   IPI00748247   
Protein Interaction databases
DIP (DOE-UCLA)Q9UPN9
IntAct (EBI)Q9UPN9
FunCoupENSG00000197323
BioGRIDTRIM33
STRING (EMBL)TRIM33
ZODIACTRIM33
Ontologies - Pathways
QuickGOQ9UPN9
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  DNA binding  ubiquitin-protein transferase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription, DNA-templated  zinc ion binding  protein ubiquitination  protein ubiquitination  ligase activity  regulation of transforming growth factor beta receptor signaling pathway  negative regulation of BMP signaling pathway  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  co-SMAD binding  R-SMAD binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  DNA binding  ubiquitin-protein transferase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  transcription, DNA-templated  zinc ion binding  protein ubiquitination  protein ubiquitination  ligase activity  regulation of transforming growth factor beta receptor signaling pathway  negative regulation of BMP signaling pathway  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  co-SMAD binding  R-SMAD binding  
NDEx NetworkTRIM33
Atlas of Cancer Signalling NetworkTRIM33
Wikipedia pathwaysTRIM33
Orthology - Evolution
OrthoDB51592
GeneTree (enSembl)ENSG00000197323
Phylogenetic Trees/Animal Genes : TreeFamTRIM33
HOVERGENQ9UPN9
HOGENOMQ9UPN9
Homologs : HomoloGeneTRIM33
Homology/Alignments : Family Browser (UCSC)TRIM33
Gene fusions - Rearrangements
Fusion : MitelmanPOSTN/TRIM33 [13q13.3/1p13.2]  [t(1;3)(p13;q13)]  
Fusion : MitelmanTRIM33/COL24A1 [1p13.2/1p22.3]  [t(1;1)(p13;p22)]  
Fusion : MitelmanTRIM33/RET [1p13.2/10q11.21]  [t(1;10)(p13;q11)]  
Fusion: TCGATRIM33 1p13.2 COL24A1 1p22.3 BRCA
Fusion: TCGATRIM33 1p13.2 RET 10q11.21 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM33 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM33
dbVarTRIM33
ClinVarTRIM33
1000_GenomesTRIM33 
Exome Variant ServerTRIM33
ExAC (Exome Aggregation Consortium)TRIM33 (select the gene name)
Genetic variants : HAPMAP51592
Genomic Variants (DGV)TRIM33 [DGVbeta]
DECIPHER (Syndromes)1:114935399-115053781  ENSG00000197323
CONAN: Copy Number AnalysisTRIM33 
Mutations
ICGC Data PortalTRIM33 
TCGA Data PortalTRIM33 
Broad Tumor PortalTRIM33
OASIS PortalTRIM33 [ Somatic mutations - Copy number]
Cancer Gene: CensusTRIM33 
Somatic Mutations in Cancer : COSMICTRIM33  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRIM33
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM33
DgiDB (Drug Gene Interaction Database)TRIM33
DoCM (Curated mutations)TRIM33 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM33 (select a term)
intoGenTRIM33
Cancer3DTRIM33(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM188550    605769   
Orphanet905   
MedgenTRIM33
Genetic Testing Registry TRIM33
NextProtQ9UPN9 [Medical]
TSGene51592
GENETestsTRIM33
Huge Navigator TRIM33 [HugePedia]
snp3D : Map Gene to Disease51592
BioCentury BCIQTRIM33
ClinGenTRIM33
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51592
Chemical/Pharm GKB GenePA38118
Clinical trialTRIM33
Miscellaneous
canSAR (ICR)TRIM33 (select the gene name)
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIM33
EVEXTRIM33
GoPubMedTRIM33
iHOPTRIM33
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:32:19 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.