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TRIM34 (tripartite motif containing 34)

Identity

Alias (NCBI)IFP1
RNF21
HGNC (Hugo) TRIM34
HGNC Previous nameRNF21
HGNC Previous nametripartite motif-containing 34
LocusID (NCBI) 53840
Atlas_Id 75150
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 5632255 and ends at 5641296 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TRIM6 (11p15.4) / TRIM34 (11p15.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRIM34   10063
Cards
Entrez_Gene (NCBI)TRIM34    tripartite motif containing 34
AliasesIFP1; RNF21
GeneCards (Weizmann)TRIM34
Ensembl hg19 (Hinxton)ENSG00000258659 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000258659 [Gene_View]  ENSG00000258659 [Sequence]  chr11:5632255-5641296 [Contig_View]  TRIM34 [Vega]
ICGC DataPortalENSG00000258659
TCGA cBioPortalTRIM34
AceView (NCBI)TRIM34
Genatlas (Paris)TRIM34
SOURCE (Princeton)TRIM34
Genetics Home Reference (NIH)TRIM34
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM34  -     chr11:5632255-5641296 +  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM34  -     11p15.4   [Description]    (hg19-Feb_2009)
GoldenPathTRIM34 - 11p15.4 [CytoView hg19]  TRIM34 - 11p15.4 [CytoView hg38]
ImmunoBaseENSG00000258659
Genome Data Viewer NCBITRIM34 [Mapview hg19]  
OMIM605684   
Gene and transcription
Genbank (Entrez)AB039902 AB039904 AF220143 AF220144 AK027876
RefSeq transcript (Entrez)NM_001003827 NM_021616 NM_130389 NM_130390
Consensus coding sequences : CCDS (NCBI)TRIM34
Gene ExpressionTRIM34 [ NCBI-GEO ]   TRIM34 [ EBI - ARRAY_EXPRESS ]   TRIM34 [ SEEK ]   TRIM34 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM34 [ Firebrowse - Broad ]
GenevisibleExpression of TRIM34 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)53840
GTEX Portal (Tissue expression)TRIM34
Human Protein AtlasENSG00000258659-TRIM34 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYJ4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYJ4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYJ4
PhosPhoSitePlusQ9BYJ4
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    B30.2/SPRY_sf    Butyrophylin_SPRY    ConA-like_dom_sf    SPRY_dom    TRIM34_PRY/SPRY    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)SPRY (PF00622)    zf-B_box (PF00643)   
Domain families : Pfam (NCBI)pfam00622    pfam00643   
Domain families : Smart (EMBL)BBOX (SM00336)  RING (SM00184)  SPRY (SM00449)  
Conserved Domain (NCBI)TRIM34
PDB (RSDB)2EGP   
PDB Europe2EGP   
PDB (PDBSum)2EGP   
PDB (IMB)2EGP   
Structural Biology KnowledgeBase2EGP   
SCOP (Structural Classification of Proteins)2EGP   
CATH (Classification of proteins structures)2EGP   
SuperfamilyQ9BYJ4
AlphaFold pdb e-kbQ9BYJ4   
Human Protein Atlas [tissue]ENSG00000258659-TRIM34 [tissue]
HPRD16141
Protein Interaction databases
DIP (DOE-UCLA)Q9BYJ4
IntAct (EBI)Q9BYJ4
BioGRIDTRIM34
STRING (EMBL)TRIM34
ZODIACTRIM34
Ontologies - Pathways
QuickGOQ9BYJ4
Ontology : AmiGOprotein polyubiquitination  molecular_function  nucleoplasm  cytoplasm  cytoplasm  cytosol  cytosol  zinc ion binding  regulation of gene expression  positive regulation of autophagy  protein ubiquitination  protein kinase binding  regulation of protein localization  identical protein binding  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  regulation of viral entry into host cell  positive regulation of DNA-binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  defense response to virus  interferon-gamma-mediated signaling pathway  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein polyubiquitination  molecular_function  nucleoplasm  cytoplasm  cytoplasm  cytosol  cytosol  zinc ion binding  regulation of gene expression  positive regulation of autophagy  protein ubiquitination  protein kinase binding  regulation of protein localization  identical protein binding  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  regulation of viral entry into host cell  positive regulation of DNA-binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  defense response to virus  interferon-gamma-mediated signaling pathway  ubiquitin protein ligase activity  
NDEx NetworkTRIM34
Atlas of Cancer Signalling NetworkTRIM34
Wikipedia pathwaysTRIM34
Orthology - Evolution
OrthoDB53840
GeneTree (enSembl)ENSG00000258659
Phylogenetic Trees/Animal Genes : TreeFamTRIM34
Homologs : HomoloGeneTRIM34
Homology/Alignments : Family Browser (UCSC)TRIM34
Gene fusions - Rearrangements
Fusion : QuiverTRIM34
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM34 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM34
dbVarTRIM34
ClinVarTRIM34
MonarchTRIM34
1000_GenomesTRIM34 
Exome Variant ServerTRIM34
GNOMAD BrowserENSG00000258659
Varsome BrowserTRIM34
ACMGTRIM34 variants
VarityQ9BYJ4
Genomic Variants (DGV)TRIM34 [DGVbeta]
DECIPHERTRIM34 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM34 
Mutations
ICGC Data PortalTRIM34 
TCGA Data PortalTRIM34 
Broad Tumor PortalTRIM34
OASIS PortalTRIM34 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM34  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIM34
Mutations and Diseases : HGMDTRIM34
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRIM34
DgiDB (Drug Gene Interaction Database)TRIM34
DoCM (Curated mutations)TRIM34
CIViC (Clinical Interpretations of Variants in Cancer)TRIM34
Cancer3DTRIM34
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605684   
Orphanet
DisGeNETTRIM34
MedgenTRIM34
Genetic Testing Registry TRIM34
NextProtQ9BYJ4 [Medical]
GENETestsTRIM34
Target ValidationTRIM34
Huge Navigator TRIM34 [HugePedia]
ClinGenTRIM34
Clinical trials, drugs, therapy
MyCancerGenomeTRIM34
Protein Interactions : CTDTRIM34
Pharm GKB GenePA35533
PharosQ9BYJ4
Clinical trialTRIM34
Miscellaneous
canSAR (ICR)TRIM34
HarmonizomeTRIM34
DataMed IndexTRIM34
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRIM34
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:26:53 CEST 2021

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