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TRIM35 (tripartite motif containing 35)

Identity

Alias (NCBI)HLS5
MAIR
HGNC (Hugo) TRIM35
HGNC Alias symbKIAA1098
MAIR
HLS5
HGNC Previous nametripartite motif-containing 35
LocusID (NCBI) 23087
Atlas_Id 46437
Location 8p21.2  [Link to chromosome band 8p21]
Location_base_pair Starts at 27284886 and ends at 27311272 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TRIM35 (8p21.2) / GSR (8p12)TRIM35 8p21.2 / GSR 8p12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRIM35   16285
Cards
Entrez_Gene (NCBI)TRIM35    tripartite motif containing 35
AliasesHLS5; MAIR
GeneCards (Weizmann)TRIM35
Ensembl hg19 (Hinxton)ENSG00000104228 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104228 [Gene_View]  ENSG00000104228 [Sequence]  chr8:27284886-27311272 [Contig_View]  TRIM35 [Vega]
ICGC DataPortalENSG00000104228
TCGA cBioPortalTRIM35
AceView (NCBI)TRIM35
Genatlas (Paris)TRIM35
SOURCE (Princeton)TRIM35
Genetics Home Reference (NIH)TRIM35
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM35  -     chr8:27284886-27311272 -  8p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM35  -     8p21.2   [Description]    (hg19-Feb_2009)
GoldenPathTRIM35 - 8p21.2 [CytoView hg19]  TRIM35 - 8p21.2 [CytoView hg38]
ImmunoBaseENSG00000104228
Genome Data Viewer NCBITRIM35 [Mapview hg19]  
OMIM617007   
Gene and transcription
Genbank (Entrez)AB029021 AF492463 AK308236 BC018337 BC069226
RefSeq transcript (Entrez)NM_001304495 NM_001362813 NM_171982
Consensus coding sequences : CCDS (NCBI)TRIM35
Gene ExpressionTRIM35 [ NCBI-GEO ]   TRIM35 [ EBI - ARRAY_EXPRESS ]   TRIM35 [ SEEK ]   TRIM35 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM35 [ Firebrowse - Broad ]
GenevisibleExpression of TRIM35 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23087
GTEX Portal (Tissue expression)TRIM35
Human Protein AtlasENSG00000104228-TRIM35 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPQ4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPQ4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPQ4
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9UPQ4
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    B30.2/SPRY_sf    Butyrophylin_SPRY    ConA-like_dom_sf    PRY    SPRY_dom    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)PRY (PF13765)    SPRY (PF00622)    zf-B_box (PF00643)   
Domain families : Pfam (NCBI)pfam13765    pfam00622    pfam00643   
Domain families : Smart (EMBL)BBOX (SM00336)  PRY (SM00589)  RING (SM00184)  SPRY (SM00449)  
Conserved Domain (NCBI)TRIM35
SuperfamilyQ9UPQ4
AlphaFold pdb e-kbQ9UPQ4   
Human Protein Atlas [tissue]ENSG00000104228-TRIM35 [tissue]
HPRD15553
Protein Interaction databases
DIP (DOE-UCLA)Q9UPQ4
IntAct (EBI)Q9UPQ4
BioGRIDTRIM35
STRING (EMBL)TRIM35
ZODIACTRIM35
Ontologies - Pathways
QuickGOQ9UPQ4
Ontology : AmiGOmolecular_function  nucleus  cytoplasm  cytoplasm  apoptotic process  zinc ion binding  protein ubiquitination  protein ubiquitination  positive regulation of apoptotic process  positive regulation of apoptotic process  innate immune response  innate immune response  negative regulation of mitotic cell cycle  ubiquitin protein ligase activity  negative regulation of viral release from host cell  
Ontology : EGO-EBImolecular_function  nucleus  cytoplasm  cytoplasm  apoptotic process  zinc ion binding  protein ubiquitination  protein ubiquitination  positive regulation of apoptotic process  positive regulation of apoptotic process  innate immune response  innate immune response  negative regulation of mitotic cell cycle  ubiquitin protein ligase activity  negative regulation of viral release from host cell  
NDEx NetworkTRIM35
Atlas of Cancer Signalling NetworkTRIM35
Wikipedia pathwaysTRIM35
Orthology - Evolution
OrthoDB23087
GeneTree (enSembl)ENSG00000104228
Phylogenetic Trees/Animal Genes : TreeFamTRIM35
Homologs : HomoloGeneTRIM35
Homology/Alignments : Family Browser (UCSC)TRIM35
Gene fusions - Rearrangements
Fusion : MitelmanTRIM35/GSR [8p21.2/8p12]  
Fusion : QuiverTRIM35
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM35 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM35
dbVarTRIM35
ClinVarTRIM35
MonarchTRIM35
1000_GenomesTRIM35 
Exome Variant ServerTRIM35
GNOMAD BrowserENSG00000104228
Varsome BrowserTRIM35
ACMGTRIM35 variants
VarityQ9UPQ4
Genomic Variants (DGV)TRIM35 [DGVbeta]
DECIPHERTRIM35 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM35 
Mutations
ICGC Data PortalTRIM35 
TCGA Data PortalTRIM35 
Broad Tumor PortalTRIM35
OASIS PortalTRIM35 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM35  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIM35
Mutations and Diseases : HGMDTRIM35
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRIM35
DgiDB (Drug Gene Interaction Database)TRIM35
DoCM (Curated mutations)TRIM35
CIViC (Clinical Interpretations of Variants in Cancer)TRIM35
Cancer3DTRIM35
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617007   
Orphanet
DisGeNETTRIM35
MedgenTRIM35
Genetic Testing Registry TRIM35
NextProtQ9UPQ4 [Medical]
GENETestsTRIM35
Target ValidationTRIM35
Huge Navigator TRIM35 [HugePedia]
ClinGenTRIM35
Clinical trials, drugs, therapy
MyCancerGenomeTRIM35
Protein Interactions : CTDTRIM35
Pharm GKB GenePA38115
PharosQ9UPQ4
Clinical trialTRIM35
Miscellaneous
canSAR (ICR)TRIM35
HarmonizomeTRIM35
DataMed IndexTRIM35
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRIM35
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:36:21 CEST 2021

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