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TRIM35 (tripartite motif containing 35)

Identity

Alias_namestripartite motif-containing 35
Alias_symbol (synonym)KIAA1098
MAIR
HLS5
Other alias
HGNC (Hugo) TRIM35
LocusID (NCBI) 23087
Atlas_Id 46437
Location 8p21.2  [Link to chromosome band 8p21]
Location_base_pair Starts at 27142403 and ends at 27168836 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TRIM35 (8p21.2) / GSR (8p12)TRIM35 8p21.2 / GSR 8p12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TRIM35   16285
Cards
Entrez_Gene (NCBI)TRIM35  23087  tripartite motif containing 35
AliasesHLS5; MAIR
GeneCards (Weizmann)TRIM35
Ensembl hg19 (Hinxton)ENSG00000104228 [Gene_View]  chr8:27142403-27168836 [Contig_View]  TRIM35 [Vega]
Ensembl hg38 (Hinxton)ENSG00000104228 [Gene_View]  chr8:27142403-27168836 [Contig_View]  TRIM35 [Vega]
ICGC DataPortalENSG00000104228
TCGA cBioPortalTRIM35
AceView (NCBI)TRIM35
Genatlas (Paris)TRIM35
WikiGenes23087
SOURCE (Princeton)TRIM35
Genetics Home Reference (NIH)TRIM35
Genomic and cartography
GoldenPath hg19 (UCSC)TRIM35  -     chr8:27142403-27168836 -  8p21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TRIM35  -     8p21.2   [Description]    (hg38-Dec_2013)
EnsemblTRIM35 - 8p21.2 [CytoView hg19]  TRIM35 - 8p21.2 [CytoView hg38]
Mapping of homologs : NCBITRIM35 [Mapview hg19]  TRIM35 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB029021 AF492463 AK308236 BC018337 BC069226
RefSeq transcript (Entrez)NM_001304495 NM_171982
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_167187 NW_004929337
Consensus coding sequences : CCDS (NCBI)TRIM35
Cluster EST : UnigeneHs.104223 [ NCBI ]
CGAP (NCI)Hs.104223
Alternative Splicing GalleryENSG00000104228
Gene ExpressionTRIM35 [ NCBI-GEO ]   TRIM35 [ EBI - ARRAY_EXPRESS ]   TRIM35 [ SEEK ]   TRIM35 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM35 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23087
GTEX Portal (Tissue expression)TRIM35
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPQ4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPQ4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPQ4
Splice isoforms : SwissVarQ9UPQ4
PhosPhoSitePlusQ9UPQ4
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    Butyrophylin    ConA-like_dom    PRY    SPRY_dom    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)PRY (PF13765)    SPRY (PF00622)    zf-B_box (PF00643)   
Domain families : Pfam (NCBI)pfam13765    pfam00622    pfam00643   
Domain families : Smart (EMBL)BBOX (SM00336)  PRY (SM00589)  RING (SM00184)  
Conserved Domain (NCBI)TRIM35
DMDM Disease mutations23087
Blocks (Seattle)TRIM35
SuperfamilyQ9UPQ4
Human Protein AtlasENSG00000104228
Peptide AtlasQ9UPQ4
HPRD15553
IPIIPI00012331   IPI00746107   IPI00974297   
Protein Interaction databases
DIP (DOE-UCLA)Q9UPQ4
IntAct (EBI)Q9UPQ4
FunCoupENSG00000104228
BioGRIDTRIM35
STRING (EMBL)TRIM35
ZODIACTRIM35
Ontologies - Pathways
QuickGOQ9UPQ4
Ontology : AmiGOmolecular_function  nucleus  cytoplasm  apoptotic process  zinc ion binding  positive regulation of apoptotic process  innate immune response  negative regulation of mitotic cell cycle  negative regulation of viral release from host cell  
Ontology : EGO-EBImolecular_function  nucleus  cytoplasm  apoptotic process  zinc ion binding  positive regulation of apoptotic process  innate immune response  negative regulation of mitotic cell cycle  negative regulation of viral release from host cell  
NDEx NetworkTRIM35
Atlas of Cancer Signalling NetworkTRIM35
Wikipedia pathwaysTRIM35
Orthology - Evolution
OrthoDB23087
GeneTree (enSembl)ENSG00000104228
Phylogenetic Trees/Animal Genes : TreeFamTRIM35
HOVERGENQ9UPQ4
HOGENOMQ9UPQ4
Homologs : HomoloGeneTRIM35
Homology/Alignments : Family Browser (UCSC)TRIM35
Gene fusions - Rearrangements
Fusion : MitelmanTRIM35/GSR [8p21.2/8p12]  
Fusion: TCGATRIM35 8p21.2 GSR 8p12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM35 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM35
dbVarTRIM35
ClinVarTRIM35
1000_GenomesTRIM35 
Exome Variant ServerTRIM35
ExAC (Exome Aggregation Consortium)TRIM35 (select the gene name)
Genetic variants : HAPMAP23087
Genomic Variants (DGV)TRIM35 [DGVbeta]
DECIPHER (Syndromes)8:27142403-27168836  ENSG00000104228
CONAN: Copy Number AnalysisTRIM35 
Mutations
ICGC Data PortalTRIM35 
TCGA Data PortalTRIM35 
Broad Tumor PortalTRIM35
OASIS PortalTRIM35 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM35  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTRIM35
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TRIM35
DgiDB (Drug Gene Interaction Database)TRIM35
DoCM (Curated mutations)TRIM35 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TRIM35 (select a term)
intoGenTRIM35
Cancer3DTRIM35(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenTRIM35
Genetic Testing Registry TRIM35
NextProtQ9UPQ4 [Medical]
TSGene23087
GENETestsTRIM35
Huge Navigator TRIM35 [HugePedia]
snp3D : Map Gene to Disease23087
BioCentury BCIQTRIM35
ClinGenTRIM35
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23087
Chemical/Pharm GKB GenePA38115
Clinical trialTRIM35
Miscellaneous
canSAR (ICR)TRIM35 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTRIM35
EVEXTRIM35
GoPubMedTRIM35
iHOPTRIM35
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:32:19 CET 2017

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