Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23087
MIM: 617007
HGNC: 16285
Ensembl: ENSG00000104228
Variants:
dbSNP: 23087
ClinVar: 23087
TCGA: ENSG00000104228
COSMIC: TRIM35
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000104228 | ENST00000305364 | Q9UPQ4 |
| ENSG00000104228 | ENST00000521253 | E5RGB3 |
| ENSG00000104228 | ENST00000521283 | H0YBF3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37578239 | 2023 | Inhibition of human adenovirus replication by TRIM35-mediated degradation of E1A. | 2 |
| 37594849 | 2023 | IRF5 promotes glycolysis in the progression of hepatocellular carcinoma and is regulated by TRIM35. | 1 |
| 37578239 | 2023 | Inhibition of human adenovirus replication by TRIM35-mediated degradation of E1A. | 2 |
| 37594849 | 2023 | IRF5 promotes glycolysis in the progression of hepatocellular carcinoma and is regulated by TRIM35. | 1 |
| 35081724 | 2022 | TRIM35 functions as a novel tumor suppressor in breast cancer by inducing cell apoptosis through ubiquitination of PDK1. | 8 |
| 36196894 | 2022 | TRIM35 ubiquitination regulates the expression of PKM2 tetramer and dimer and affects the malignant behaviour of breast cancer by regulating the Warburg effect. | 7 |
| 35081724 | 2022 | TRIM35 functions as a novel tumor suppressor in breast cancer by inducing cell apoptosis through ubiquitination of PDK1. | 8 |
| 36196894 | 2022 | TRIM35 ubiquitination regulates the expression of PKM2 tetramer and dimer and affects the malignant behaviour of breast cancer by regulating the Warburg effect. | 7 |
| 34124276 | 2021 | Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration. | 5 |
| 34124276 | 2021 | Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration. | 5 |
| 32293015 | 2020 | Tripartite motif containing 35 contributes to the proliferation, migration, and invasion of lung cancer cells in vitro and in vivo. | 4 |
| 32293015 | 2020 | Tripartite motif containing 35 contributes to the proliferation, migration, and invasion of lung cancer cells in vitro and in vivo. | 4 |
| 28394882 | 2017 | miR-4417 Targets Tripartite Motif-Containing 35 (TRIM35) and Regulates Pyruvate Kinase Muscle 2 (PKM2) Phosphorylation to Promote Proliferation and Suppress Apoptosis in Hepatocellular Carcinoma Cells. | 23 |
| 28394882 | 2017 | miR-4417 Targets Tripartite Motif-Containing 35 (TRIM35) and Regulates Pyruvate Kinase Muscle 2 (PKM2) Phosphorylation to Promote Proliferation and Suppress Apoptosis in Hepatocellular Carcinoma Cells. | 23 |
| 25263439 | 2015 | TRIM35 Interacts with pyruvate kinase isoform M2 to suppress the Warburg effect and tumorigenicity in hepatocellular carcinoma. | 41 |
Citation
Dessen P
TRIM35 (tripartite motif containing 35)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46437/trim35
