Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TRIM38 (tripartite motif containing 38)

Identity

Alias (NCBI)RNF15
RORET
HGNC (Hugo) TRIM38
HGNC Alias symbRORET
HGNC Previous nameRNF15
HGNC Previous namering finger protein 15
 tripartite motif-containing 38
LocusID (NCBI) 10475
Atlas_Id 54723
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 25962802 and ends at 25991229 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BEND6 (6p12.1) / TRIM38 (6p22.2)DST (6p12.1) / TRIM38 (6p22.2)TRIM38 (6p22.2) / KIAA0232 (4p16.1)
DST 6p12.1 / TRIM38 6p22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TRIM38   10059
Cards
Entrez_Gene (NCBI)TRIM38    tripartite motif containing 38
AliasesRNF15; RORET
GeneCards (Weizmann)TRIM38
Ensembl hg19 (Hinxton)ENSG00000112343 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112343 [Gene_View]  ENSG00000112343 [Sequence]  chr6:25962802-25991229 [Contig_View]  TRIM38 [Vega]
ICGC DataPortalENSG00000112343
TCGA cBioPortalTRIM38
AceView (NCBI)TRIM38
Genatlas (Paris)TRIM38
SOURCE (Princeton)TRIM38
Genetics Home Reference (NIH)TRIM38
Genomic and cartography
GoldenPath hg38 (UCSC)TRIM38  -     chr6:25962802-25991229 +  6p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TRIM38  -     6p22.2   [Description]    (hg19-Feb_2009)
GoldenPathTRIM38 - 6p22.2 [CytoView hg19]  TRIM38 - 6p22.2 [CytoView hg38]
ImmunoBaseENSG00000112343
Genome Data Viewer NCBITRIM38 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AB209906 AK310777 AK313248 BC026930 BX640949
RefSeq transcript (Entrez)NM_006355
Consensus coding sequences : CCDS (NCBI)TRIM38
Gene ExpressionTRIM38 [ NCBI-GEO ]   TRIM38 [ EBI - ARRAY_EXPRESS ]   TRIM38 [ SEEK ]   TRIM38 [ MEM ]
Gene Expression Viewer (FireBrowse)TRIM38 [ Firebrowse - Broad ]
GenevisibleExpression of TRIM38 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10475
GTEX Portal (Tissue expression)TRIM38
Human Protein AtlasENSG00000112343-TRIM38 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00635   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00635  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00635
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusO00635
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    ZF_BBOX (PS50119)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)B30.2/SPRY    B30.2/SPRY_sf    Butyrophylin_SPRY    ConA-like_dom_sf    PRY    SPRY/PRY_TRIM38    SPRY_dom    Znf_B-box    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)PRY (PF13765)    SPRY (PF00622)    zf-B_box (PF00643)   
Domain families : Pfam (NCBI)pfam13765    pfam00622    pfam00643   
Domain families : Smart (EMBL)BBOX (SM00336)  PRY (SM00589)  RING (SM00184)  SPRY (SM00449)  
Conserved Domain (NCBI)TRIM38
SuperfamilyO00635
AlphaFold pdb e-kbO00635   
Human Protein Atlas [tissue]ENSG00000112343-TRIM38 [tissue]
HPRD15555
Protein Interaction databases
DIP (DOE-UCLA)O00635
IntAct (EBI)O00635
BioGRIDTRIM38
STRING (EMBL)TRIM38
ZODIACTRIM38
Ontologies - Pathways
QuickGOO00635
Ontology : AmiGOprotein polyubiquitination  transcription coactivator activity  protein binding  cellular_component  nucleoplasm  cytoplasm  cytosol  cytosol  zinc ion binding  regulation of gene expression  positive regulation of autophagy  protein ubiquitination  protein kinase binding  regulation of protein localization  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  positive regulation of transcription, DNA-templated  regulation of viral entry into host cell  positive regulation of viral entry into host cell  positive regulation of DNA-binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  positive regulation of NF-kappaB transcription factor activity  interferon-gamma-mediated signaling pathway  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein polyubiquitination  transcription coactivator activity  protein binding  cellular_component  nucleoplasm  cytoplasm  cytosol  cytosol  zinc ion binding  regulation of gene expression  positive regulation of autophagy  protein ubiquitination  protein kinase binding  regulation of protein localization  protein homodimerization activity  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  positive regulation of transcription, DNA-templated  regulation of viral entry into host cell  positive regulation of viral entry into host cell  positive regulation of DNA-binding transcription factor activity  positive regulation of NF-kappaB transcription factor activity  positive regulation of NF-kappaB transcription factor activity  interferon-gamma-mediated signaling pathway  ubiquitin protein ligase activity  
NDEx NetworkTRIM38
Atlas of Cancer Signalling NetworkTRIM38
Wikipedia pathwaysTRIM38
Orthology - Evolution
OrthoDB10475
GeneTree (enSembl)ENSG00000112343
Phylogenetic Trees/Animal Genes : TreeFamTRIM38
Homologs : HomoloGeneTRIM38
Homology/Alignments : Family Browser (UCSC)TRIM38
Gene fusions - Rearrangements
Fusion : MitelmanBEND6/TRIM38 [6p12.1/6p22.2]  
Fusion : MitelmanDST/TRIM38 [6p12.1/6p22.2]  
Fusion : QuiverTRIM38
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTRIM38 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TRIM38
dbVarTRIM38
ClinVarTRIM38
MonarchTRIM38
1000_GenomesTRIM38 
Exome Variant ServerTRIM38
GNOMAD BrowserENSG00000112343
Varsome BrowserTRIM38
ACMGTRIM38 variants
VarityO00635
Genomic Variants (DGV)TRIM38 [DGVbeta]
DECIPHERTRIM38 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTRIM38 
Mutations
ICGC Data PortalTRIM38 
TCGA Data PortalTRIM38 
Broad Tumor PortalTRIM38
OASIS PortalTRIM38 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTRIM38  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTRIM38
Mutations and Diseases : HGMDTRIM38
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTRIM38
DgiDB (Drug Gene Interaction Database)TRIM38
DoCM (Curated mutations)TRIM38
CIViC (Clinical Interpretations of Variants in Cancer)TRIM38
Cancer3DTRIM38
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETTRIM38
MedgenTRIM38
Genetic Testing Registry TRIM38
NextProtO00635 [Medical]
GENETestsTRIM38
Target ValidationTRIM38
Huge Navigator TRIM38 [HugePedia]
ClinGenTRIM38
Clinical trials, drugs, therapy
MyCancerGenomeTRIM38
Protein Interactions : CTDTRIM38
Pharm GKB GenePA35532
PharosO00635
Clinical trialTRIM38
Miscellaneous
canSAR (ICR)TRIM38
HarmonizomeTRIM38
DataMed IndexTRIM38
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTRIM38
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:36:21 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.